scholarly journals Safety of Deep Sedation with General Anesthesia for Minor Invasive Procedures in Pediatric Hematology/Oncology Patients

2018 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Tuysuz Gulen ◽  
Tayfun Funda
Keyword(s):  
General Anesthesia ◽  
Deep Sedation ◽  
Invasive Procedures ◽  
Oncology Patients ◽  
Pediatric Hematology

Nosocomial infections among pediatric hematology/oncology patients: Results of a prospective incidence study

2004 ◽  
Vol 32 (4) ◽  
pp. 205-208 ◽  
Author(s):  
Mireya Urrea ◽  
Susana Rives ◽  
Ofelia Cruz ◽  
Albert Navarro ◽  
Juan José Garcı́a ◽  
...  
Keyword(s):  
Incidence Study ◽  
Nosocomial Infections ◽  
Oncology Patients ◽  
Pediatric Hematology

Prospective analysis of urokinase in the treatment of catheter sepsis in pediatric hematology-oncology patients

1993 ◽  
Vol 28 (3) ◽  
pp. 350-357 ◽  
Author(s):  
Gary R. Jones ◽  
Gwen K. Konsler ◽  
Rose P. Dunaway ◽  
Stuart R. Lacey ◽  
Richard G. Azizkhan
Keyword(s):  
Prospective Analysis ◽  
Oncology Patients ◽  
Pediatric Hematology ◽  
Catheter Sepsis

Is Childhood General Anesthesia Exposure An Etiological Contributor to Cognitive Impairment?

2021 ◽  
Vol 36 (3) ◽  
pp. 251-259
Author(s):  
Yi Tian ◽  
Peiyu Liu ◽  
Weisong Liu ◽  
Qiaojing Xu ◽  
Xiangkun Zhao
Keyword(s):  
Risk Factors ◽  
Early Childhood ◽  
Cognitive Impairment ◽  
General Anesthesia ◽  
Strong Correlation ◽  
Clinical Studies ◽  
Clinical Evidence ◽  
Preclinical Studies ◽  
Invasive Procedures ◽  
Immature Brain

General anesthesia is necessary for patients to undergo surgery and invasive procedures. However, numerous preclinical studies have demonstrated widespread developmental neurotoxicity of the commonly used anesthetics and sedatives for the immature brain. Clinical studies also suggest a strong correlation between childhood anesthesia exposure and subsequent behavioral or cognitive impairment in adulthood. These findings have attracted increasing attention of anesthesiologists, pediatricians, and caregivers about the safety of anesthesia exposure in children, especially during early childhood. Herein, the aim of this review was to present the molecular mechanism of general anesthesia and its effects on the developing brain and introduce the recent clinical evidence of changes in cognition function post-childhood general anesthesia exposure. More importantly, some of the spots will be importantly discussed to scrutinize the phenomena; only in this way, it may help minimize or eliminate relevant risk factors.

Surveillance for Nosocomial and Central Line-Related Infections Among Pediatric Hematology-Oncology Patients

2000 ◽  
Vol 21 (9) ◽  
pp. 592-596 ◽  
Author(s):  
Arne Simon ◽  
Gudrun Fleischhack ◽  
Carola Hasan ◽  
Udo Bode ◽  
Steffen Engelhart ◽  
...  
Keyword(s):  
Infection Control ◽  
Home Care ◽  
Nosocomial Infections ◽  
Surveillance System ◽  
Severe Neutropenia ◽  
Prospective Surveillance ◽  
Surveillance Period ◽  
Oncology Patients ◽  
Pediatric Hematology ◽  
Significant Difference

AbstractObjective:To determine the incidence of all nosocomial infections (NIs) in pediatric hematology-oncology patients, as well as central venous access device (CVAD)-associated infections acquired during home care.Design:Prospective surveillance study.Setting:The Pediatric Hematology and Oncology Department at the University Hospital Bonn.Patients:All patients admitted from January through October 1998 (surveillance period).Methods:Standardized surveillance system based on the Centers for Disease Control and Prevention's National Nosocomial Infections Surveillance System.Results:A total of 143 patients were hospitalized for 3,701 days (776 admissions) during the surveillance period. Of the 40 NIs detected, 26 were CVAD-related, with 21 bloodstream infections (BSIs) and 5 local infections. Four were Clostridium difficile-associated diarrheal illnesses, 3 were pneumonias, and 7 were other infections. The incidence of NIs was 10.8 per 1,000 patient-days (5.2 NIs/100 admissions). The overall CVAD-related BSI rate was 7.4 per 1,000 utilization days, without a significant difference between implanted infusion ports and tunneled catheters. In addition, 7 CVAD-related infections occurred during home care. All 8 BSIs associated with tunneled catheters and 13 (76%) of the 17 BSIs associated with ports were acquired nosocomially. For inpatients and outpatients combined, the exit sites of tunneled catheters were more likely to become locally infected than were the needle entry sites of ports (relative risk, 8.0; P=.007). In 30 (75%) of the 40 NIs, the affected patients had severe neutropenia (<500/mm3) at the time of infection.Conclusions:Most NIs in the pediatric hematology-oncology patients were associated with CVAD devices. Although many infections in this high-risk population may not be preventable through infection control measures, the careful evaluation of specific infection rates permits the identification of risk factors that may be targeted by infection control programs. Prospective surveillance for NIs on pediatric oncology units is an indispensable tool for this internal quality control.

scholarly journals Oral Health Care Delivery for Children During COVID-19 Pandemic—A Retrospective Study

2021 ◽  
Vol 9 ◽  
Author(s):  
Avia Fux-Noy ◽  
Luna Mattar ◽  
Aviv Shmueli ◽  
Elinor Halperson ◽  
Diana Ram ◽  
...  
Keyword(s):  
General Anesthesia ◽  
Behavior Management ◽  
Deep Sedation ◽  
Care Delivery ◽  
Medical Center ◽  
Pediatric Dentistry ◽  
Control Measures ◽  
Healthy Children ◽  
Efficient Treatment ◽  
Dental Staff

Aim: COVID-19 outbreak and the lockdown period following was a very challenging time for pediatric dentistry. We aimed to find whether the characteristics of dental care provided to children at the Department of Pediatric Dentistry at Hadassah medical center, Jerusalem, Israel, differed between the periods, before COVID-19 outbreak, during the lockdown period and during the period that followed it.Materials and Methods: We retrospectively reviewed computerized records of patients who visited the pediatric dental clinic at three different periods: pre-lockdown period, lockdown period, and post-lockdown period.Results: Nine-hundred and forty-nine children were included in the study; most of them were healthy children between 3 and 6 years old. During lockdown, all scheduled appointments except for treatments under general anesthesia and deep sedation were canceled due to the government's restrictions; the frequency of treatments with non-pharmacological behavior management, general anesthesia or deep sedation was higher than in the previous or subsequent periods and the use of inhaled/conscious sedation was significantly lower. During lockdown most of the children were diagnosed with dentoalveolar abscess (32.3%), compared to 14 and 21% at the previous or subsequent periods, respectively (P &lt; 0.001). Treatments combination during lockdown included more extractions, pulpectomies and pulp extirpation and less permanent restorations (P &lt; 0.001). None of the staff members was infected with COVID-19 at the clinic during these periods. We concluded that dentists should be updated about Covid-19 modes of transmission and the recommended infection control measures in dental settings. Effective management protocols can help the dental staff to continue to provide efficient treatment and prevent Covid-19 contamination.

Office-based ambulatory anesthesia: Factors that influence patient satisfaction or dissatisfaction with deep sedation/general anesthesia

2005 ◽  
Vol 63 (2) ◽  
pp. 163-172 ◽  
Author(s):  
Timothy T. Coyle ◽  
John F. Helfrick ◽  
Martin L. Gonzalez ◽  
Randi V. Andresen ◽  
David H. Perrott
Keyword(s):  
Patient Satisfaction ◽  
General Anesthesia ◽  
Deep Sedation ◽  
Ambulatory Anesthesia

An Outbreak of Mycobacterium mucogenicum Bacteremia in Pediatric Hematology-oncology Patients

2011 ◽  
Vol 30 (1) ◽  
pp. 30-32 ◽  
Author(s):  
Yael Shachor-Meyouhas ◽  
Hannah Sprecher ◽  
Orna Eluk ◽  
Ayelet Ben-Barak ◽  
Imad Kassis
Keyword(s):  
Oncology Patients ◽  
Pediatric Hematology ◽  
Mycobacterium Mucogenicum

scholarly journals Professional Skills and Competence for Safe and Effective Procedural Sedation in Children: Recommendations Based on a Systematic Review of the Literature

2010 ◽  
Vol 2010 ◽  
pp. 1-16 ◽  
Author(s):  
Piet L. J. M. Leroy ◽  
Daphne M. Schipper ◽  
Hans (J.) T. A. Knape
Keyword(s):  
Systematic Review ◽  
Deep Sedation ◽  
Procedural Sedation ◽  
Evidence Based ◽  
Review Of Literature ◽  
Invasive Procedures ◽  
Professional Skills ◽  
Serious Adverse Events ◽  
Set Up ◽  
Design And Methods

Objectives. To investigate which skills and competence are imperative to assure optimal effectiveness and safety of procedural sedation (PS) in children and to analyze the underlying levels of evidence.Study Design and methods. Systematic review of literature published between 1993 and March 2009. Selected papers were classified according to their methodological quality and summarized in evidence-based conclusions. Next, conclusions were used to formulate recommendations.Results. Although the safety profiles vary among PS drugs, the possibility of potentially serious adverse events and the predictability of depth and duration of sedation define the imperative skills and competence necessary for a timely recognition and appropriate management. The level of effectiveness is mainly determined by the ability to apply titratable PS, including deep sedation using short-acting anesthetics for invasive procedures and nitrous oxide for minor painful procedures, and the implementation of non-pharmacological techniques.Conclusions. PS related safety and effectiveness are determined by the circumstances and professional skills rather than by specific pharmacologic characteristics. Evidence based recommendations regarding necessary skills and competence should be used to set up training programs and to define which professionals can and cannot be credentialed for PS in children.

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