scholarly journals Efficacy of Noninvasive Positive Pressure Ventilation for Improving the Respiratory Function, Use of Accessory Respiratory Muscles, Quality of Sleep and Nutrition of Cystic Fibrosis Patients

2017 ◽  
Vol 27 (4) ◽  
Author(s):  
Maryam Hassanzad ◽  
Shahram Kharabian Masouleh ◽  
Sabereh Tashayoie Nejad ◽  
Saba Karimzadeh ◽  
Ali Akbar Velayati
Keyword(s):  
Cystic Fibrosis ◽  
Respiratory Function ◽  
Positive Pressure Ventilation ◽  
Noninvasive Positive Pressure Ventilation ◽  
Respiratory Muscles ◽  
Positive Pressure ◽  
Quality Of Sleep ◽  
Accessory Respiratory Muscles

scholarly journals Successful management of dyspnea in a patient with stiff person syndrome with noninvasive positive-pressure ventilation: A case report

2021 ◽  
Vol 26 (4) ◽  
pp. 849-852
Author(s):  
Du Hwan Kim ◽  
Min Cheol Chang
Keyword(s):  
Positive Pressure Ventilation ◽  
Therapeutic Option ◽  
Noninvasive Positive Pressure Ventilation ◽  
Respiratory Muscles ◽  
Gas Analysis ◽  
Muscle Stiffness ◽  
Positive Pressure ◽  
Stiff Person Syndrome ◽  
Arterial Blood Gas ◽  
Arterial Blood

Approximately half of patients with stiff person syndrome experienced dyspnea due to the involvement of the respiratory muscles. If these muscles are severely affected, respiratory failure can occur. Here, we describe a patient with stiff person syndrome whose nighttime dyspnea was successfully controlled by noninvasive positive-pressure ventilation (NIPPV). A 38-year-old female patient visited the emergency room due to nighttime dyspnea. Her O2 saturation was 93%, and PaCO2 increased to 53.4 mmHg on arterial blood gas analysis. No specific lesion was found on the chest radiograph. We considered that her dyspnea was caused by respiratory muscle stiffness following SPS. For the management of nighttime hypercapnia, we applied NIPPV with volume-targeted assist-control ventilation mode using an oronasal mask interface during sleep. After such treatment, PaCO2 was normalized, and nighttime dyspnea disappeared. We think that NIPPV would be a useful therapeutic option for managing dyspnea induced by stiff person syndrome.

Internet of things-based home noninvasive positive pressure ventilation in COPD patients with hypercapnic chronic respiratory failure: study protocol for a multicenter randomized controlled trial

2021 ◽  
Author(s):  
Weipeng Jiang ◽  
Yuanlin Song
Keyword(s):  
Quality Of Life ◽  
Respiratory Failure ◽  
Positive Pressure Ventilation ◽  
Controlled Trial ◽  
Noninvasive Positive Pressure Ventilation ◽  
Positive Pressure ◽  
Hypercapnic Respiratory Failure ◽  
Randomized Controlled ◽  
Copd Patients

Abstract BackgroundHome noninvasive positive pressure ventilation (NIPPV) have become evidence-based care for stable hypercapnic chronic obstructive pulmonary disease (COPD) patients. There are still other challenges including appropriate follow-up, telemonitor and management to ensure treatment effectiveness, compliance and security, and to improve quality of life. The Internet of Things (IOT) is the name given to the network of devices and other “things” with built-in sensors, software, electronics and network connectivity, communicating these objects over wireless networks and sending data to a cloud platform. The study aims to evaluate the effectiveness and safety of the IOT-based management of NIPPV for the COPD patients with hypercapnic chronic respiratory failure.MethodsThis multicenter, prospective, randomized controlled trial will be conducted with a total of 200 COPD patients with chronic hypercapnic respiratory failure. Using a computer-generated randomization process, patients will be randomized (in a 1:1 ratio) into usual NIPPV (control group) or to receive additional IOT-based management (intervention group) for 12 months. The primary outcome is Severe Respiratory Insufficiency (SRI) questionnaire. Secondary outcomes include compliance with the ventilator, gas exchange, lung function, Health-related Quality of Life, hospitalization frequency, time to death within 1-year, all-cause mortality, safety analysis and cost-effectiveness analysis.DiscussionThis study will be the first and largest randomized trial in China to evaluate the effectiveness and safety of the IOT-based management of NIPPV for COPD patients with chronic hypercapnic respiratory failure. The results will help to understand the current situation of IOT based home ventilation and may provide new evidence for home NIPPV treatment and management in the future.Trial registrationChinese Clinical Trials Registry ChiCTR1800019536. Registered 17 November, 2018.

scholarly journals Comparison of outcomes of high-flow nasal cannula and noninvasive positive-pressure ventilation in patients with hypoxemia and various APACHE II scores after extubation

2021 ◽  
Vol 15 ◽  
pp. 175346662110042
Author(s):  
Xiaoke Shang ◽  
Yanggan Wang
Keyword(s):  
Positive Pressure Ventilation ◽  
Noninvasive Positive Pressure Ventilation ◽  
Abdominal Distension ◽  
Apache Ii ◽  
Positive Pressure ◽  
Apache Ii Score ◽  
Subgroup Ii ◽  
Significant Difference ◽  
Group A ◽  
Group B

Aims: The study aimed to compare and analyze the outcomes of high-flow nasal cannula (HFNC) and noninvasive positive-pressure ventilation (NPPV) in the treatment of patients with acute hypoxemic respiratory failure (AHRF) who had extubation after weaning from mechanical ventilation. Methods: A total 120 patients with AHRF were enrolled into this study. These patients underwent tracheal intubation and mechanical ventilation. They were organized into two groups according to the score of Acute Physiologic Assessment and Chronic Health Evaluation II (APACHE II); group A: APACHE II score <12; group B: 12⩽ APACHE II score <24. Group A had 72 patients and patients given HFNC were randomly assigned to subgroup I while patients given NPPV were assigned to subgroup II (36 patients in each subgroup). Group B had 48 patients and patients given HFNC were randomly assigned to subgroup I while patients given NPPV were assigned to subgroup II (24 patients in each subgroup). General information, respiratory parameters, endpoint event, and comorbidities of adverse effect were compared and analyzed between the two subgroups. Results: The incidence of abdominal distension was significantly higher in patients treated with NPPV than in those treated with HFNC in group A (19.44% versus 0, p = 0.005) and group B (25% versus 0, p = 0.009). There was no significant difference between the HFNC- and NPPV-treated patients in blood pH, oxygenation index, partial pressure of carbon dioxide, respiratory rate, and blood lactic acid concentration in either group ( p > 0.05). Occurrence rate of re-intubation within 72 h of extubation was slightly, but not significantly, higher in NPPV-treated patients ( p > 0.05). Conclusion: There was no significant difference between HFNC and NPPV in preventing respiratory failure in patients with AHRF with an APACHE II score <24 after extubation. However, HFNC was superior to NPPV with less incidence of abdominal distension. The reviews of this paper are available via the supplemental material section.

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