scholarly journals The Risk Factors and Incidence of Type 2 Diabetes Mellitus and Metabolic Syndrome in Women With Previous Gestational Diabetes

Author(s):  
Majid Valizadeh ◽  
Nooshin Alavi ◽  
Saeideh Mazloomzadeh ◽  
Zahra Piri ◽  
Hamidreza Amirmoghadami
Author(s):  
Eman Basiouny ◽  
Faiza Lashin ◽  
Manal Hamisa ◽  
Amal Selim

Aims: To assess hepatic steatosis and fibrosis in patients of type 2 diabetes mellitus (T2DM), their possible risk factors and their association with metabolic syndrome and micro or macro-albuminuria. Study Design: Cross sectional study. Place and Duration of Study: Outpatient Clinic of Diabetes, Metabolism and Endocrinology Unit in internal medicine department, Tanta University, Egypt in a period between September 2019 to March 2020. Methodology: We included 200 patients had a diagnosis of T2DM according to American Diabetes Association criteria. Then patients were assessed for presence of hepatic steatosis and fibrosis using fibroscan and we used liver stiffness measurements (LSMs, as a measure of fibrosis) and controlled attenuation parameter (CAP, as a measure of steatosis) and routine laboratory data were done to rule out possible risk factors. Results: 98.5% of participants had hepatic steatosis and 53.5% of participants had hepatic fibrosis. Those patients had longer duration of DM, higher BMI, bad control of T2DM, higher lipid profile values, association with metabolic syndrome, micro and macro-albuminuria and non-significantly elevated liver enzymes. Conclusion: Hepatic steatosis and fibrosis are highly prevalent in patients with T2DM, incidence of hepatic steatosis and fibrosis is positively correlated with longer duration of DM, higher BMI, bad control of DM, dyslipidemia, presence of metabolic syndrome, diabetic nephropathy, weakly correlated with liver enzymes. TE is an accurate and non-invasive tool to be used in screening for hepatic steatosis and fibrosis ,so we recommend screening for hepatic steatosis and fibrosis using fibroscan to help in early management and prevent its progression into liver cirrhosis.


Author(s):  
Chao-Hsien Lee ◽  
Peng-Lin Tseng ◽  
Wei-Ting Chang ◽  
Yi-Chien Chen ◽  
Tsai-Tung Chiu

IntroductionThis study was aimed at analyzing, modeling, and comparing the risk factors of diabetic retinopathy (DR) among type 2 diabetes mellitus (DM) patients with and without metabolic syndrome (MS).Material and methodsA cross-sectional study from July 2017 to July 2019 was performed by tracing type 2 DM patients who received treatment at an out-patient clinic and a mydriatic examination by an ophthalmologist in a single institute in south Taiwan. A total of 802 patients without DR were recruited and divided into two groups based on whether they had MS for this study. We analyzed the impact of DR based on the potential and related factors of these two groups.ResultsThe sample consisted of 802 patients; 282 patients did not have MS, and 520 did. A comparison of the risk factors of DR among the patients with and without MS revealed that the level of glycated hemoglobin (HbA1c) was a co-risk factor of DR. However, female sex, betel quid chewing, family history of DM, and higher total cholesterol were found to be risk factors of DR among the patients who had MS. Betel quid chewing, especially, could exacerbate the disease condition of DM and elevate the risk of DR.ConclusionsOf those risk factors, betel quid chewing may be the main reason for DM deterioration and raised risk of DR. Hence, we recommend that the chewing of betel quid should be avoided to prevent DR.


2015 ◽  
Vol 22 (2) ◽  
pp. 201-207 ◽  
Author(s):  
Carmen Dobjanschi ◽  
Rucsandra Dănciulescu Miulescu

AbstractWomen with gestational diabetes mellitus (GDM) have an increased lifetime risk of developing type 2 diabetes mellitus (T2DM). GDM has a substantial impact on maternal and foetal short and long-term health. Risk factors for GDM may be genetic or nongenetic and have been analysed in numerous studies. Researches in recent years allowed the identification of other risk factors for GDM except for those already known. Knowledge and identification of all risk factors for GDM allows the elaboration of a prevention strategy of T2DM, it may influence the screening, diagnosis, and, subsequently, treatment modalities for this disease.


2020 ◽  
Vol 67 (4) ◽  
pp. 427-437
Author(s):  
Maki Kawasaki ◽  
Naoko Arata ◽  
Naoko Sakamoto ◽  
Anna Osamura ◽  
Siori Sato ◽  
...  

2018 ◽  
Vol 13 (6) ◽  
pp. 582-586 ◽  
Author(s):  
Moeber M. Mahzari ◽  
Fahad A. Alwadi ◽  
Basil M. Alhussain ◽  
Tariq M. Alenzi ◽  
Aamir A. Omair ◽  
...  

2017 ◽  
Vol Volume 10 ◽  
pp. 47-55 ◽  
Author(s):  
Michael J Davies ◽  
Katherine W Merton ◽  
Ujjwala Vijapurkar ◽  
Dainius A. Balis ◽  
Mehul Desai

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