scholarly journals Efficacy of Different Protocols of Radioiodine Therapy for Treatment of Toxic Nodular Goiter: Systematic Review and Meta-Analysis of the Literature

2014 ◽  
Vol 12 (2) ◽  
Author(s):  
Haleh Rokni ◽  
Ramin Sadeghi ◽  
Zohreh Moossavi ◽  
Giorgio Treglia ◽  
Seyed Rasoul Zakavi
Keyword(s):  
Systematic Review ◽  
Radioiodine Therapy ◽  
Meta Analysis ◽  
Nodular Goiter ◽  
Toxic Nodular Goiter

MORTALITY RISK AFTER RADIOIODINE THERAPY FOR HYPERTHYROIDISM: A SYSTEMATIC REVIEW AND META-ANALYSIS

2020 ◽  
Author(s):  
Dandan Yan ◽  
Chuang Chen ◽  
Honglin Yan ◽  
Tian Liu ◽  
Hong Yan ◽  
...  
Keyword(s):  
Systematic Review ◽  
Mortality Risk ◽  
Radioiodine Therapy ◽  
Meta Analysis

scholarly journals Radioiodine therapy outcome in toxic multinodular goiter patient with concomitant hereditary Hasharon hemoglobinopathy

2020 ◽  
Vol 66 (3) ◽  
pp. 27-32
Author(s):  
Dali S. Dzeytova ◽  
Stanislav S. Shklyaev ◽  
Pavel O. Rumyantsev ◽  
Marina S. Sheremeta ◽  
Alexey A. Trukhin ◽  
...  
Keyword(s):  
Radionuclide Therapy ◽  
Radioiodine Therapy ◽  
Nodular Goiter ◽  
Thyroid Stimulating Hormone ◽  
Drug Induced ◽  
Toxic Nodular Goiter ◽  
Toxic Multinodular Goiter ◽  
History Of ◽  
Abnormal Hemoglobin ◽  
Heterozygous Form

This research describes a clinical case of treatment of a patient with thyrotoxicosis with concomitant hematological pathology carriage of unstable hemoglobin Hasharon. A patient diagnosed with Diffuse toxic nodular goiter. Thyrotoxicosis of medium severity. Drug-induced hypothyroidism was admitted to the Department of radionuclide therapy for the purpose of treatment with radioactive iodine. Onset of disease - summer 2018 (thyroid-stimulating hormone (TSH) 0 mIU/ml). The instrumental studies (ultrasound, scintillation scanning of the thyroid gland) were performed at the pre-radioiodine therapy (RIT) diagnostic stage. The history of the disease indicates, that in 2000 the patient was suspected of having abnormal hemoglobin, since then no examinations have been conducted and anemia has never been detected. The diagnosis of ancestral hemoglobinopathy with the presence (17%) of unstable Hasharon-Sinai-Sealy hemoglobin in a heterozygous form was verified during the preparation to RIT. The radionuclide therapy I131 with activity of 400 MBq was performed on 02.07.2019. The monthly monitoring of laboratory and instrumental indicants was carried out during the post-therapeutic period: the state of hypothyroidism was reached by the end of 2 months after RT, no episodes of significant increase in bilirubin levels were observed during the observation period; no side effects from RT were stated. It becomes possible based on the example of the above observation, to judge the safety of conducting RT for treatment of thyrotoxicosis in patients with similar hemoglobinopathy, without excluding, however, the need for an individual approach in each case.

Management of multinodular goiter in Germany (Papillon 2005)

2007 ◽  
Vol 46 (03) ◽  
pp. 65-75
Author(s):  
K. Wegscheider ◽  
R. Vaupel ◽  
M. Schmidt ◽  
H. Schicha ◽  
M. Dietlein
Keyword(s):  
Primary Care ◽  
Multinodular Goiter ◽  
Large Scale ◽  
Radioiodine Therapy ◽  
Nodular Goiter ◽  
Diagnostic Procedures ◽  
Needle Aspiration ◽  
Toxic Nodular Goiter ◽  
Needle Aspiration Cytology ◽  
Calcitonin Screening

Summary Aim: Large-scale survey to focus on management of multinodular goiter and to compare the approaches of practitioners in primary care and thyroid specialists in Germany. Methods: Replies to a questionnaire were received from 2,191 practitioners and 297 thyroid specialists between June 1 and September 30, 2005. The hypothetical cases and their modifications described multinodular goiters of different sizes with and without toxic nodules. Results: In the workup, TSH determination and thyroid sonography were found to be standard procedures. Scintigraphy was selected by 80.2% of practitioners and 92.9% of specialists (p <0.001), in preference to fine needle aspiration cytology (17.9% of practitioners and 34.5% of the specialists, p <0.001). Only 6.1% of practitioners and 24.4% of specialists (p <0.001) advocated calcitonin screening. Euthyroid multinodular goiter (50-80 ml) was treated medically by 67.1% of practitioners and 65.6% of specialists, the combination of levothyroxine with iodine being clearly preferred (54.5% of practitioners, 52.3% of specialists). For toxic nodular goiter the preference for radioiodine therapy was significantly higher (p <0.001) among specialists (67.7%) than among practitioners (47.5%). Referral to surgery was recommended for cold nodules with negative cytology by 64.9% of practitioners and 73.5% of specialists (p = 0.004). Conclusions: Treatment and diagnostic procedures are used to nearly the same extent in primary care and specialist institutions, but the opinions diverge over the issues of calcitonin screening and referral for radioiodine therapy.

scholarly journals Clinical characteristics associated with the finding of thyroid cancer originating from hot nodules in patients with hyperthyroidism: a case report and systematic review of the literature

2021 ◽  
Vol 36 (4) ◽  
pp. 682-695
Author(s):  
Carlos Osorio ◽  
Jorge Ballestas ◽  
Diego Barrios ◽  
Andrés Arévalo ◽  
Shekyna Montaño ◽  
...  
Keyword(s):  
Systematic Review ◽  
Thyroid Cancer ◽  
Malignant Tumors ◽  
Nodular Goiter ◽  
Follicular Carcinoma ◽  
Toxic Nodular Goiter ◽  
Factors Associated ◽  
Diagnosis Of Cancer ◽  
Nodular Lesions ◽  
Diagnosis Of Thyroid Cancer

Coexistence between thyroid cancer and hyperthyroidism is rare, and most of the nodular lesions from which a malignant tumor is documented in this group of patients correspond to cold nodules. Justified by the increasing number of reports in the literature about malignant tumors diagnosed from hot nodules, a systematic review was carried out to determine possible factors associated with the diagnosis of thyroid cancer from hot nodules in patients with hyperthyroidism. The results suggest that the clinical diagnosis of toxic nodular goiter, nodular lesions of diameter > 10 mm and a histological type compatible with a follicular carcinoma, are factors that on their own increase the risk of making the diagnosis of cancer from a hot nodule.

The effects of low-ratio n-6/n-3 PUFA on biomarkers of inflammation: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Yali Wei ◽  
Yan Meng ◽  
Na Li ◽  
Qian Wang ◽  
Liyong Chen
Keyword(s):  
Systematic Review ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acid ◽  
Meta Analysis ◽  
Chain Polyunsaturated Fatty Acid ◽  
Inflammation Markers ◽  
Pufa Supplementation ◽  
Long Chain

The purpose of the systematic review and meta-analysis was to determine if low-ratio n-6/n-3 long-chain polyunsaturated fatty acid (PUFA) supplementation affects serum inflammation markers based on current studies.

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