The Epidemiology of Candida Species Isolated From Urinary Tract Infections

2016 ◽  
Vol 11 (4) ◽  
Author(s):  
Mohammad Salehi ◽  
Abdolmajid Ghasemian ◽  
Seyyed Khalil Shokouhi Mostafavi ◽  
Farshad Nojoomi ◽  
Danial Ashiani ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Candida Species ◽  
Tract Infections

scholarly journals Prevalence and Antifungal Susceptibility Pattern of Candida species Isolated from Patients with Urinary Tract Infections

2021 ◽  
Vol 7 (4) ◽  
pp. 328-335
Author(s):  
IA Lawal ◽  
OA Osinupebi ◽  
OV Adeosun
Keyword(s):  
Candida Albicans ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Candida Species ◽  
Antifungal Susceptibility ◽  
Diffusion Method ◽  
Susceptibility Pattern ◽  
Agar Disc ◽  
Sensitivity Pattern ◽  
Tract Infections

Background: The presence of Candida species in the urine is termed candiduria, and it is a common form of urinary tract infection (UTI). Many other species of Candida organism apart from Candida albicans are known with increasing the occurrence of resistance to available antifungal agents. Objectives: To determine the prevalence and sensitivity pattern of Candida isolates obtained from urine samples of diagnosed urinary tract infections. Methods: Midstream urine of patients attending the Lagos University Teaching Hospital, Ikeja Lagos, were collected and inoculated on Sabouraud Dextrose Agar (SDA). Microbiological processing was done with Gram reaction, germ tube test, CHROME agar TM and sugar fermentation test using API 32C system. Antifungal susceptibility tests were done using the agar disc diffusion method. Results: Candida species were obtained from 36 (12.9%) of 280 patients with UTI. Candida albicans (CA) had the highest frequency (12; 33.3%) compared to 24 (66.7%) for Non-albicans Candida (NAC). The speciation of Candida using Chrome Agar showed some misidentification from the API32C identification, but there was a significant correlation between API32C and Chrome Agar methods (r = 0. 9793). Half of the C. albicans species were sensitive to fluconazole while C. hellenica was only sensitive to Nystatin. The C. parapsilopsis had the highest susceptibility pattern, with 86% and 71% for fluconazole and ketoconazole, respectively. Generally, ketoconazole had the highest effectiveness on Candida species. Conclusion: This study demonstrated the role of Candida species in UTIs and their high susceptibility to ketoconazole.

scholarly journals Urinary Isolates and Antifungal Susceptibility Pattern of Candida species Isolated from Patients in Tertiary Care

2021 ◽  
pp. 48-56
Author(s):  
A. Arasi Samyuktha ◽  
V. Illamani ◽  
Chitralekha Saikumar
Keyword(s):  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Candida Species ◽  
Culture Media ◽  
Fungal Infections ◽  
Antifungal Susceptibility ◽  
Tertiary Care ◽  
Hospitalized Patients ◽  
Common Finding ◽  
Tract Infections

Community-acquired urinary tract infections (UTIs) are fastidious growing infections caused by Candida fungal overgrowth that frequently occur in immunosuppressed hospital patients. Although many factors account for the increases in these fungal infections, the leading causes include the rise in medical device usage, immunosuppressant drugs, and interventional procedures. The emergence of drug resistant in Candidal species, which is largely attributed to use of prolonged and inappropriate empirical therapy, has further complicated patient management. The regularity of urinary tract infections (UTIs) due to Candida species is growing and these infections are most common clinical outcome, particularly in hospitalized patients. The microbiological invasions in any tissue of the urinary tract extend from the renal cortex to the urethral meatus. Candida UTI or candiduria is a common finding in hospitalized patients. To find out the ratio of Candida albicans to non- albicans Candida species to correlate the risk factors to the Candida species associated and to analyze the speciation of Candida isolates using the Chrom agar is a differential culture media, with sugar assimilation test. Constant surveillance of candiduria is important as C. tropicalis is more invasive, can lead to fatal candidemia. Identification of Candida up to species level is essential, as it can give an idea to the clinicians about appropriate antifungal therapy. Our study showed a predominance of non-albicans Candida spp. of about 86%. C. tropicalis (62%) was the most common isolate obtained followed by C. albicans (14%), C. glabrata (10%), C. krusei (9%) and C. parapsilosis (5%). Indwelling urinary catheter was an important associated risk factor for non-albicans candiduria.

scholarly journals Isolation, characterization, and molecular identification of Candida species from urinary tract infections

2019 ◽  
Author(s):  
Amin Gharanfoli ◽  
Elaheh Mahmoudi ◽  
Roya Torabizadeh ◽  
Roya Torabizadeh ◽  
Farzad Katiraii ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Candida Species ◽  
Fungal Pathogens ◽  
Fungal Infections ◽  
Glucose Absorption ◽  
Fungal Species ◽  
Predisposing Factors ◽  
Predisposing Factor ◽  
Tract Infections

Short communication Background and Purpose: Candida species are reportedly the most common human fungal pathogens. The incidence of urinary tract infections (UTIs) caused by Candida pathogens has increased in recent decades. However, such infections rarely occur in the absence of any predisposing factors. Regarding this, the aim of the present study was to identify the Candida species causing UTIs and determine the predisposing factors for candiduria. Materials and Methods: The current study was conducted on 1,450 urine samples obtained from patients suspected of UTI. Out of this number, 19 cases were candidiasis, and 2 cases were mixed infections caused by bacteria and fungi. Candida species were diagnosed differentially using the germ tube test, colony staining on CHROMagar medium, intracellular beta-glucosidase enzyme activity, and glucose absorption pattern. Then, the colonies with the same morphology were confirmed by the DNA sequencing of internal transcribed spacer regions. Results: According to the results, 38%, 28.6%, 14.3%, and 9.5% of the isolates were identified as C. albicans, C. glabrata, C. tropicalis, and C. kefir/C. krusei, respectively. The presence of one or more predisposing factors was proved in all patients in whom diabetes was the most prevalent predisposing factor (21.1%). Conclusion: Based on the obtained results, C. albicans species was the most prevalent fungal species. In addition, urinary fungal infections were less prevalent than bacterial urinary infections.

Candidal urinary tract infections caused by non-albicans Candida species

2002 ◽  
Vol 47 (2) ◽  
pp. 182-184 ◽  
Author(s):  
E. Dorko ◽  
E. Pilipčinec ◽  
L'. Tkáčiková
Keyword(s):  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Candida Species ◽  
Tract Infections
Sign in / Sign up

Export Citation Format

Share Document