scholarly journals Impact of Vitamin C Supplementation on Post-Cardiac Surgery ICU and Hospital Length of Stay

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Anita Sadeghpour ◽  
Azin Alizadehasl ◽  
Majid Kyavar ◽  
Tahereh Sadeghi ◽  
Jalal Moludi ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Length Of Stay ◽  
Vitamin C ◽  
Hospital Length ◽  
Hospital Length Of Stay ◽  
Vitamin C Supplementation ◽  
Post Cardiac Surgery

scholarly journals Effects of Vitamin C on Organ Function in Cardiac Surgery Patients: A Systematic Review and Meta-Analysis

Nutrients ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 2103 ◽  
Author(s):  
Aileen Hill ◽  
Kai C. Clasen ◽  
Sebastian Wendt ◽  
Ádám G. Majoros ◽  
Christian Stoppe ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Cardiac Surgery ◽  
Length Of Stay ◽  
Vitamin C ◽  
Hospital Mortality ◽  
Organ Dysfunction ◽  
Meta Analysis ◽  
Hospital Length ◽  
Hospital Length Of Stay ◽  
Organ Function

Background: Cardiac surgery is associated with oxidative stress and systemic inflammation, which both contribute to postoperative organ dysfunction. Vitamin C is a pleiotropic, antioxidant, and potentially organ-protective micronutrient. Past clinical trials and meta-analyses have focused predominantly on occurrence of postoperative atrial fibrillation. Therefore, we investigated the influence of perioperative vitamin C administration on clinically relevant parameters closer related to the patient’s recovery, especially organ function, and overall outcomes after cardiac surgery. Methods: Randomized controlled trials (RCTs) comparing perioperative vitamin C administration versus placebo or standard of care in adult patients undergoing cardiac surgery were identified through systematic searches in Pubmed, EMBASE, and CENTRAL on 23 November 2018. Published and unpublished data were included. Assessed outcomes include organ function after cardiac surgery, adverse events, in-hospital mortality, intensive care unit, and hospital length-of-stay. Data was pooled only when appropriate. Results: A total of 19 RCTs with 2008 patients were included in this meta-analysis. Vitamin C significantly decreased the incidence of atrial fibrillation (p = 0.008), ventilation time (p < 0.00001), ICU length-of-stay (p = 0.004), and hospital length-of-stay (p < 0.0001). However, on average, vitamin C had no significant effects on in-hospital mortality (p = 0.76), or on the incidence of stroke (p = 0.82). High statistical heterogeneity was observed in most analyses. Conclusions: Vitamin C impacts clinically and economically important outcomes, such as ICU and hospital length-of-stay, duration of mechanical ventilation and lowers the incidence of atrial fibrillation. Due to missing reports on organ dysfunction, this meta-analysis cannot answer the question, if vitamin C can improve single- or multiorgan function after cardiac surgery.

MORBIDITY ASSOCIATED WITH PROLONGED HOSPITAL LENGTH OF STAY FOLLOWING CARDIAC SURGERY

1998 ◽  
Vol 86 (Supplement) ◽  
pp. 50SCA
Author(s):  
M Panah ◽  
LA Andres ◽  
SA Strope ◽  
F Vela-Cantos ◽  
E Bennett-Guerrero
Keyword(s):  
Cardiac Surgery ◽  
Length Of Stay ◽  
Hospital Length ◽  
Hospital Length Of Stay ◽  
Prolonged Hospital

scholarly journals Lactate levels after major cardiac surgery are associated with hospital length of stay

Critical Care ◽  
2015 ◽  
Vol 19 (Suppl 1) ◽  
pp. P193
Author(s):  
LW Andersen ◽  
M Holmberg ◽  
P Patel ◽  
KM Berg ◽  
M Cocchi ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Length Of Stay ◽  
Hospital Length ◽  
Hospital Length Of Stay ◽  
Lactate Levels

Predictors of extubation failure after open-chest cardiac surgery based on routinely collected data. The importance of a shared interprofessional clinical assessment

2018 ◽  
Vol 17 (8) ◽  
pp. 751-759 ◽  
Author(s):  
Gianfranco Sanson ◽  
Massimiliano Sartori ◽  
Lorella Dreas ◽  
Roberta Ciraolo ◽  
Adam Fabiani
Keyword(s):  
Cardiac Surgery ◽  
Length Of Stay ◽  
Invasive Mechanical Ventilation ◽  
Extubation Failure ◽  
Hospital Length ◽  
Neurological Function ◽  
Hospital Length Of Stay ◽  
Rapid Shallow Breathing Index ◽  
Shallow Breathing ◽  
Rapid Shallow Breathing

Background: Extubation failure (ExtF) is associated with prolonged hospital length of stay and mortality in adult cardiac surgery patients postoperatively. In this population, ExtF-related variables such as the arterial partial pressure of oxygen to fraction of inspired oxygen ratio (PaO2/FiO2), rapid shallow breathing index, cough strength, endotracheal secretions and neurological function have been sparsely researched. Aim: To identify variables that are predictive of ExtF and related outcomes. Method: Prospective observational longitudinal study. Consecutively presenting patients ( n=205) undergoing open-heart cardiac surgery and admitted to the Cardiosurgical Intensive Care Unit (CICU) were recruited. The clinical data were collected at CICU admission and immediately prior to extubation. ExtF was defined as the need to restart invasive or non-invasive mechanical ventilation while the patient was in the CICU. Results: The ExtF incidence was 13%. ExtF related significantly to hospital mortality, CICU length of stay and total hospital length of stay. The risk of ExtF decreased significantly, by 93% in patients with good neurological function and by 83% in those with a Rapid Shallow Breathing Index of ≥57 breaths/min per litre. Conversely, ExtF risk increased 27 times when the PaO2/FiO2 was <150 and 11 times when it was ≥450. Also, a reassuring PaO2/FiO2 value may hide critical pulmonary or extra-pulmonary conditions independent from alveolar function. Conclusion: The decision to extubate patients should be taken after thoroughly discussing and combining the data derived from nursing and medical clinical assessments. Extubation should be delayed until the patient achieves safe respiratory, oxygenation and haemodynamic conditions, and good neurocognitive function.

Postoperative Lactate Levels and Hospital Length of Stay After Cardiac Surgery

2015 ◽  
Vol 29 (6) ◽  
pp. 1454-1460 ◽  
Author(s):  
Lars W. Andersen ◽  
Mathias J. Holmberg ◽  
Michelle Doherty ◽  
Kamal Khabbaz ◽  
Adam Lerner ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Length Of Stay ◽  
Hospital Length ◽  
Hospital Length Of Stay ◽  
Lactate Levels

scholarly journals Preoperative hospital length of stay as a modifiable risk factor for mediastinitis after cardiac surgery

2013 ◽  
Vol 8 (1) ◽  
Author(s):  
Stephane Leung Wai Sang ◽  
Rakesh Chaturvedi ◽  
Ahsan Alam ◽  
Gordan Samoukovic ◽  
Benoit de Varennes ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Risk Factor ◽  
Length Of Stay ◽  
Hospital Length ◽  
Hospital Length Of Stay ◽  
Modifiable Risk Factor
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