scholarly journals Erythrophagocytosis in Bone Marrow: A Clue to Pyrexia of Unknown Origin

2018 ◽  
pp. 73-75
Author(s):  
Neha Garg ◽  
Surabhi Raina ◽  
Mrinalini Kotru ◽  
Meera Sikka
Keyword(s):  
Bone Marrow ◽  
Unknown Origin ◽  
Pyrexia Of Unknown Origin

scholarly journals UNCOMMON PRESENTATION OF A COMMON DISEASE AS PUO

2020 ◽  
pp. 51-52
Author(s):  
Y.V.S. Prabhakar ◽  
Ponnaganti Vasundhara
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Aspiration ◽  
Unknown Origin ◽  
Common Disease ◽  
Peripheral Smear ◽  
Laboratory Findings ◽  
Pyrexia Of Unknown Origin ◽  
Uncommon Presentation ◽  
Blood Smears ◽  
Peripheral Blood Smears

We report a case of pyrexia of unknown origin in a 35 yr old male . He presented to us with fever since 2 months which was associated with chills and rigor . He is non alcoholic , non smoker . Mild Hepatosplenomegaly was found on initial physical examination. Before he was referred to our hospital, he was investigated in outside hospital . The serial Rapid Diagnostic Test and microscopic peripheral blood smears for plasmodium were negative . He was treated symptomatically . In view of non subsiding fever patient was referred to higher centre . He presented to our institute for further evaluation . His laboratory findings found pancytopenia. Bone marrow aspiration(BMA) was done. BMA showed Gametocytes of P. falciparum. The presence of gametocytes of P.Falciparum in the bone marrow ,not in peripheral smear and presenting as PUO is rare .

scholarly journals Bone marrow granuloma in a child with pyrexia of unknown origin: A clue for diagnosis of brucellosis

2019 ◽  
Vol 62 (3) ◽  
pp. 493
Author(s):  
Deepak Bansal ◽  
Renu Suthar ◽  
Deepti Suri ◽  
Prashant Sharma ◽  
Pallab Ray
Keyword(s):  
Bone Marrow ◽  
Unknown Origin ◽  
Pyrexia Of Unknown Origin ◽  
Bone Marrow Granuloma

scholarly journals Value of Bone marrow Examination in Pyrexia of unknown origin

2013 ◽  
Vol 3 (6) ◽  
pp. 447-451 ◽  
Author(s):  
A Jha ◽  
R Sarda
Keyword(s):  
Bone Marrow ◽  
Megaloblastic Anemia ◽  
Unknown Origin ◽  
Bone Marrow Examination ◽  
Common Finding ◽  
Morphological Examination ◽  
Diagnostic Dilemma ◽  
Serological Tests ◽  
Pyrexia Of Unknown Origin ◽  
Diagnostic Modalities

Background: Pyrexia of unknown origin is a common diagnostic dilemma. Series of diagnostic modalities are required to arrive at diagnosis. Bone marrow examination is one of the common tests implicated in the diagnosis in combination with other diagnostic modalities. Present study has attempted to explore the causes of pyrexia of unknown origin based on bone marrow morphological study. Materials and Methods: In a one year prospective study conducted at Manipal Teaching Hospital, Pokhara, Nepal; bone marrow aspiration and biopsy was performed and evaluated morphologically, in 57 patients fulfilling the criteria of classic pyrexia of unknown origin. Results: In 42% cases; specific diagnosis could be made and hematological neoplasm was the most common finding followed by megaloblastic anemia, hypoplastic anemia and one case each of hemophagocytosis, malaria and tuberculosis. Acute leukemia was the most frequently encountered hematological malignancy followed by multiple myeloma, chronic myeloid leukemia, essential thrombocythemia and myelodysplastic syndrome. Conclusion: Morphological examination of bone marrow has important role in diagnosis of pyrexia of unknown origin. However, yield of diagnosis can be increased if it is combined with other diagnostic modalities including radiological, microbiological and serological tests. DOI: http://dx.doi.org/10.3126/jpn.v3i6.8991 Journal of Pathology of Nepal (2013) Vol. 3, 447-451

scholarly journals Filariasis in Bone Marrow Aspiration of a Child with Pyrexia of Unknown Origin – A Case Report

2014 ◽  
Vol 13 (12) ◽  
pp. 01-03
Author(s):  
Dr Sangeeta Sharma ◽  
◽  
Dr Ujwala Maheshwari ◽  
Dr Pooja Gajaria ◽  
Dr Reeta Dhar ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Case Report ◽  
Bone Marrow Aspiration ◽  
Unknown Origin ◽  
Pyrexia Of Unknown Origin

Hematological profile in pyrexia of unknown origin: role of bone marrow trephine biopsy vis-à-vis aspiration

Hematology ◽  
2008 ◽  
Vol 13 (5) ◽  
pp. 307-312 ◽  
Author(s):  
Ruchika Gupta ◽  
Namrata Setia ◽  
Prerna Arora ◽  
Sompal Singh ◽  
Tejinder Singh
Keyword(s):  
Bone Marrow ◽  
Unknown Origin ◽  
Trephine Biopsy ◽  
Bone Marrow Trephine ◽  
Pyrexia Of Unknown Origin ◽  
Bone Marrow Trephine Biopsy ◽  
Hematological Profile

scholarly journals Unusual Manifestation of Extrapulmonary Tuberculosis

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Aisha A. Alghamdi ◽  
Faiza S. Awan ◽  
Iqbal H. Maniyar ◽  
Naif A. Alghamdi
Keyword(s):  
Bone Marrow ◽  
Extrapulmonary Tuberculosis ◽  
Unknown Origin ◽  
Bone Marrow Examination ◽  
Leukemoid Reaction ◽  
Unusual Manifestation ◽  
Pyrexia Of Unknown Origin ◽  
Antituberculosis Treatment ◽  
History Of ◽  
Severe Pancytopenia

Though commonly encountered, extrapulmonary tuberculosis (TB) can sometimes present with variable clinical picture intricating the diagnosis (Avasthi et al., 2010). The nonspecific symptoms include pyrexia of unknown origin, hepatosplenomegaly, lymphadenopathy, meningitis, and, rarely, variety of hematological abnormalities, namely, anemia, pancytopenia, and leukemoid reaction (Avasthi et al., 2010). When it presents with bone marrow (BM) involvement, prognosis is usually poor (Avasthi et al., 2010, Qasim et al., 2003, and Singh et al., 2001). We, hereby, report a case of extra-pulmonary TB with a six-month history of fever associated with dizziness, fatigability, and cough. During the hospital stay, the patient showed a spectrum of interesting hematological findings, including severe pancytopenia on peripheral smear, necrotizing caseating granulomas consistent with TB on bone marrow examination. The patient showed a good clinical as well as hematological response to antituberculosis treatment. This paper highlights the significance of a hematological picture in the final confirmation of TB, which may otherwise be passed off as nutritional or other unrelated causes.

Sign in / Sign up

Export Citation Format

Share Document