A case of salivary duct carcinoma exhibiting sarcomatoid changes in the metastatic lesions

2018 ◽  
Vol 57 (1) ◽  
pp. 39-44
Author(s):  
Kaori UETA ◽  
Nobuo HOSHI ◽  
Kimiko NAKANO ◽  
Yukiko OGURA ◽  
Miho KOBAYASHI ◽  
...  
2021 ◽  
pp. 343-346
Author(s):  
Tsuyoshi Sato ◽  
Takahiro Maeta ◽  
Ryosuke Abe ◽  
Hiroyuki Yamada ◽  
Kazuyuki Ishida ◽  
...  

Salivary duct carcinoma (SDC) is a rare and highly aggressive malignancy. A 58-year-old man presented with a right-sided submandibular mass and metastatic lesions in the right supraclavicular and inferior internal jugular nodes. He underwent right submandibulectomy and right neck dissection followed by adjuvant chemoradiotherapy. However, relapse occurred in the hilar lymph node and lumbar spine. Although radiotherapy was performed, a second relapse appeared in the hilar lymph nodes and sacral bone. Immunohistochemical analysis revealed negativity for programmed death ligand-1 (PD-L1) in the primary tumor specimen. The patient then received the anti-programmed death-1 (PD-1) antibody nivolumab. His metastatic lesions were completely eliminated after 48 weeks of therapy. This case reveals that anti-PD-1 antibodies are effective even against PD-L1-negative SDC.


2019 ◽  
Author(s):  
W van Boxtel ◽  
S Lütje ◽  
AC van Engen-van Grunsven ◽  
GW Verhaegh ◽  
JA Schalken ◽  
...  

Author(s):  
Kyung Yeon Kim ◽  
Hae Sang Park ◽  
Sung Min Chung ◽  
Han Su Kim

2019 ◽  
Vol 35 (1) ◽  
pp. 13-20
Author(s):  
Yong Ju Lee ◽  
Yoon Woo Koh ◽  
Sun Och Yoon ◽  
Hyang Joo Ryu ◽  
Hye Ryun Kim ◽  
...  

2021 ◽  
Author(s):  
Keisuke Sato ◽  
Mai Matsumura ◽  
Yoko Anzai ◽  
Hiromasa Arai ◽  
Motoki Sekiya ◽  
...  

Head & Neck ◽  
2021 ◽  
Author(s):  
Gustavo Schvartsman ◽  
Diana Bell ◽  
Maria Laura Rubin ◽  
Michael Tetzlaff ◽  
Ehab Hanna ◽  
...  

Cancer ◽  
2005 ◽  
Vol 103 (12) ◽  
pp. 2526-2533 ◽  
Author(s):  
Michael Jaehne ◽  
Kerstin Roeser ◽  
Thorsten Jaekel ◽  
Jan David Schepers ◽  
Natalie Albert ◽  
...  

2015 ◽  
Vol 144 (0) ◽  
pp. 112-113
Author(s):  
Satoshi Koyama ◽  
Kazunori Fujiwara ◽  
Takahiro Fukuhara ◽  
Eiji Tekeuchi ◽  
Hiroya Kitano

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Kimihide Kusafuka ◽  
Hidetaka Yamada ◽  
Keiko Ishino ◽  
Matsuyoshi Maeda ◽  
Koji Yamanegi ◽  
...  

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