Cytologic findings of breast mucinous carcinoma (pure type, type B) in liquid based fine needle aspiration cytology

2017 ◽  
Vol 56 (6) ◽  
pp. 283-288
Author(s):  
Satoko NAGAO ◽  
Yukari MAEDA ◽  
Manami KAIKURA ◽  
Yoko KITAZONO ◽  
Kazuhito HATANAKA ◽  
...  
2012 ◽  
Vol 2 (4) ◽  
pp. 285-288
Author(s):  
RC Adhikari ◽  
A Jha

Background: Pure mucinous carcinoma is a rare histologic type of mammary neoplasm and may exist as mixed mucinous-ductal carcinoma. This study aims to describe fine needle aspiration cytology features of mucinous carcinoma of breast diagnosed in Tribhuvan University Teaching Hospital, Nepal over the period of 2 years and to correlate with histological findings.Materials and Methods: There were a total of 8 cases of mucinous carcinoma of breast, diagnosed on fine needle aspiration cytology in TUTH during the period from April 2010 to March 2012. The patient’s age, laterality of involvement, fine needle aspiration cytology features, gross and histological findings, type of surgery performed and tumor size were evaluated. Fine needle aspiration cytology smears were evaluated for cellularity, amount of mucin, chicken-wire vasculature and nuclear atypia.Results: Fine needle aspiration cytology provided a pre-operative diagnosis of mucinous carcinoma in 5 cases and mixed mucinous carcinoma-invasive ductal carcinoma in 3 cases. Histological examination showed pure mucinous carcinoma in 3 cases, mixed mucinous carcinoma-invasive ductal carcinoma in 4 cases and mixed cribriform carcinoma and ductal carcinoma in 1 case.Conclusion: Mucinous carcinoma may appear clinically and radiologically benign and fine needle aspiration cytology plays important role in the correct pre-operative diagnosis. Significant nuclear pleomorphism and necrosis, in addition to extracellular mucin suggests mixed mucinous carcinomainvasive ductal carcinoma.Journal of Pathology of Nepal (2012) Vol. 2, 285-288DOI: http://dx.doi.org/10.3126/jpn.v2i4.6879


2017 ◽  
Vol 45 (10) ◽  
pp. 934-938 ◽  
Author(s):  
Subrata Pal ◽  
Palash Kr Mondal ◽  
Rajashre Pradhan ◽  
Abhishek Sharma ◽  
Biswajit Biswas ◽  
...  

Breast Cancer ◽  
1996 ◽  
Vol 3 (1) ◽  
pp. 53-56
Author(s):  
Masafumi Kurosumi ◽  
Hideto Era ◽  
Yusaku Sano ◽  
Yoshio Kuwashima ◽  
Kiyozo Kishi ◽  
...  

2014 ◽  
Vol 19 (2) ◽  
pp. 110-118
Author(s):  
Mohammad Amzad Hossain ◽  
Md Zahedul Alam ◽  
Md Rojibul Haque ◽  
Md Nazmul Haque ◽  
KM Nurul Alam ◽  
...  

Objective: To evaluate the role of Fine Needle Aspiration Cytology in the preoperative diagnosis of malignancy in parotid and submandibular gland neoplasm. Methods: This cross sectional study on 50 cases was conducted in the Department of Otolaryngology and Head-Neck Surgery of Sir Salimullah Medical College Mitford Hospital and Dhaka Medical College Hospital from January’2009 to June 2010. Results: Fine needle aspiration cytology findings of our all 50 cases were compared with postoperative histopathological reports. Out of the 50 cases, in 36(72%) cases of benign neoplasm and 7(14%) cases of malignant neoplasm, pre-operative FNAC findings and post operative histopathological findings were same. In 7 cases, FNAC and post operative histopathological findings did not matched. These were 2 (4%) false positive and 5 (10%) false negative result.In our study sensitivity of FNAC for reporting malignancy was 58.33%, specificity to rule out malignancy was 94.73% and overall accuracy in detecting malignant tumour was 86%. Positive predictive value and negative value were 77.77% and 87.80% respectively. It can be concluded that fine needle aspiration cytology is a safe, cheap and useful preoperative diagnostic tool in the diagnosis of malignancy in parotid and submandibular gland, but as fine needle aspiration cytology partly depends on operator skill, it may give false negative and false positive result. Conclusion: FNAC is a useful preoperative diagnostic tool for malignant parotid and submandibular glands with high specificity and sensitivity. DOI: http://dx.doi.org/10.3329/bjo.v19i2.17634 Bangladesh J Otorhinolaryngol 2013; 19(2): 110-118


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