Combination of wing-typed centrifuge tube and BD CytoRichTM improves cell concentration and diagnostic accuracy in urinary cytology

2017 ◽  
Vol 56 (6) ◽  
pp. 271-275
Author(s):  
Miyaka UMEMORI ◽  
Takashi UMEZAWA ◽  
Ayana HORIGUCHI ◽  
Sachiko TSUCHIYA ◽  
Setsuko HARUMA ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Cell Concentration ◽  
Urinary Cytology ◽  
Centrifuge Tube

scholarly journals Noninvasive Electromagnetic Detection of Bladder Cancer

ISRN Urology ◽  
2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Luigi Cormio ◽  
Clarbruno Vedruccio ◽  
Giorgio Leucci ◽  
Paolo Massenio ◽  
Giuseppe Di Fino ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Diagnostic Accuracy ◽  
Predictive Value ◽  
False Negative ◽  
Electromagnetic Properties ◽  
Urinary Cytology ◽  
Predictive Values ◽  
Electromagnetic Detection ◽  
Voiding Symptoms ◽  
Asymptomatic Patients

Objectives. Normal and neoplastic human tissues have different electromagnetic properties. This study aimed to determine the diagnostic accuracy of noninvasive electromagnetic detection of bladder cancer (BC) by the tissue-resonance interaction method (TRIM-prob). Patients and Methods. Consecutive patients were referred for cystoscopy because of (i) microscopic or gross hematuria and/or irritative voiding symptoms and (ii) bladder ultrasounds and urinary cytology findings negative or just suspicious of malignancy. Patients were first submitted to TRIM-prob bladder scanning by a single investigator and then to cystoscopy by another investigator blind to TRIM-prob data. Results. In 125 evaluated patients cystoscopy was positive for BC in 47 and negative in the remaining 78; conversely, TRIM-prob bladder scanning was positive for BC in 53 and negative in 72. In particular, TRIM-prob scanning yielded 7 false positives and only one false negative; therefore, its overall sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy were 97.9%, 89.9%, 86.8%, 98.6%, and 93.6%, respectively. Conclusions. TRIM-prob bladder scanning was a simple and quite accurate method for non-invasive electromagnetic detection of BC. If the elevated positive and negative predictive values will be replicated in further well-designed studies, it could be used to screen asymptomatic patients at high risk of BC.

Immunocyt Test Improves the Diagnostic Accuracy of Urinary Cytology: Results of a French Multicenter Study

2003 ◽  
Vol 169 (3) ◽  
pp. 921-924 ◽  
Author(s):  
CHRISTIAN PFISTER ◽  
DENIS CHAUTARD ◽  
MARIAN DEVONEC ◽  
PAUL PERRIN ◽  
DOMINIQUE CHOPIN ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Multicenter Study ◽  
Urinary Cytology

Diagnostic Accuracy of Urinary Cytology, and Deoxyribonucleic Acid Flow Cytometry and Cytology on Bladder Washings During Followup for Bladder Tumors

1997 ◽  
Vol 157 (5) ◽  
pp. 1660-1664 ◽  
Author(s):  
Mireille Gregoire ◽  
Yves Fradet ◽  
Francois Meyer ◽  
Bernard Tetu ◽  
Richard Bois ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Diagnostic Accuracy ◽  
Deoxyribonucleic Acid ◽  
Urinary Cytology ◽  
Bladder Tumors

Significance of 5-Aminolevulinic Acid-mediated Photodynamic Diagnosis Following Standard Transurethral Resection in Non-muscle Invasive Bladder Cancer

2021 ◽  
Vol 1 (3) ◽  
pp. 201-205
Author(s):  
KYOHEI WATANABE ◽  
KEITA TAMURA ◽  
YUTO MATSUSHITA ◽  
HIROMITSU WATANABE ◽  
DAISUKE MOTOYAMA ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Diagnostic Accuracy ◽  
Transurethral Resection ◽  
Aminolevulinic Acid ◽  
Photodynamic Diagnosis ◽  
Urinary Cytology ◽  
Residual Cancer ◽  
Muscle Invasive Bladder Cancer ◽  
Muscle Invasive ◽  
Additional Resection

Background/Aim: Transurethral resection of bladder tumors (TURBT) guided by photodynamic diagnosis (PDD) with 5-aminolevulinic acid (5-ALA) has been shown to be superior to conventional white light (WL) cystoscopy with regard to diagnostic accuracy, for non-muscle invasive bladder cancer (NMIBC); however, PDD is usually performed prior to WL TURBT. The objective of this study was to investigate the diagnostic significance of 5-ALA-mediated PDD following TUR of NMIBC. Patients and Methods: In 83 NMIBC patients, all visible tumors were completely resected under the conventional WL guidance followed by additional resection if fluorescent lesions were observed under the blue light (BL) guidance, and random biopsy was further conducted. Results: With the BL source, 39 (47.0%) patients were judged to have fluorescent lesions. Twenty (51.3%) of the 39 patients with positive findings by PDD were diagnosed with residual cancer by additional resection, while random biopsy detected cancers in 2 (4.5%) of the 44 patients with negative findings by PDD. Accordingly, the sensitivity, specificity, positive predictive value and negative predictive value in diagnosing residual cancer by our PDD system were 90.9, 68.9, 51.3 and 95.5%, respectively. Univariate analysis showed that the presence of residual cancers shown by WL TURBT was significantly associated with the preoperative findings of urinary cytology, tumor multiplicity, pathological T stage and tumor grade, of which only the preoperative finding on urinary cytology was shown to have an independent impact on the diagnosis of residual cancer. Conclusion: 5-ALA-mediated PDD following standard WL TURBT could improve the diagnostic accuracy in NMIBC patients, particularly those who are positive for preoperative urinary cytology.

Upper urinary tract tumours: Latest diagnostic methods

1996 ◽  
Vol 63 (1) ◽  
pp. 29-35
Author(s):  
M. Carini ◽  
E. Palminteri ◽  
G.P. Mincione ◽  
A. Lapini ◽  
S. Serni ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Diagnostic Accuracy ◽  
Upper Urinary Tract ◽  
Diagnostic Methods ◽  
Urinary Cytology ◽  
Low Grade ◽  
Brush Biopsy ◽  
Cellular Analysis ◽  
Long Time ◽  
Cytology Brush

— The diagnostic and therapeutic approach to upper urinary tract tumours has been a problem for a long time. The recent introduction of endourological instruments (ureterorenoscopy), the possibility of well-aimed cellular analysis (selective urinary cytology, brush biopsy) as well as the development of imaging methods, have all improved the accuracy of diagnosis and staging with the consequent rationalisation of treatment. Using ureterorenoscopy in addition to the main diagnostic examinations for this pathology i.e. urinary cytology and urography, diagnostic accuracy has increased from 58 to over 85%. This allows identification of early, single and low grade forms, which are susceptible to conservative, possibly endoscopic, treatment.

Diagnostic accuracy of DNA image cytometry and urinary cytology with cells from voided urine in the detection of bladder cancer

Urology ◽  
2000 ◽  
Vol 56 (5) ◽  
pp. 782-786 ◽  
Author(s):  
Bernhard Planz ◽  
Christian Synek ◽  
Joachim Robben ◽  
Alfred Böcking ◽  
Michael Marberger
Keyword(s):  
Bladder Cancer ◽  
Diagnostic Accuracy ◽  
Image Cytometry ◽  
Urinary Cytology ◽  
Dna Image Cytometry
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