Histological outcome of women in the categories of atypical squamous cells (ASC) and atypical glandular cells (AGC) in The Bethesda System

2012 ◽  
Vol 51 (1) ◽  
pp. 42-48
Author(s):  
Takako KIYOKAWA
Keyword(s):  
Squamous Cells ◽  
Glandular Cells ◽  
Atypical Glandular Cells ◽  
Bethesda System ◽  
The Bethesda System

Incidence of Atypical Glandular Cells of Uncertain Significance in Cervical Cytology Following Introduction of the Bethesda System

1997 ◽  
Vol 67 (1) ◽  
pp. 51-55 ◽  
Author(s):  
Gary L. Eddy ◽  
Serdar H. Ural ◽  
Kenneth B. Strumpf ◽  
Martha A. Wojtowycz ◽  
Pamela S. Piraino ◽  
...  
Keyword(s):  
Cervical Cytology ◽  
Uncertain Significance ◽  
Glandular Cells ◽  
Atypical Glandular Cells ◽  
Bethesda System ◽  
The Bethesda System

scholarly journals Bethesda System Reporting Rates for Conventional Papanicolaou Tests and Liquid-Based Cytology in a Large Chinese, College of American Pathologists–Certified Independent Medical Laboratory: Analysis of 1 394 389 Papanicolaou Test Reports

2015 ◽  
Vol 139 (3) ◽  
pp. 373-377 ◽  
Author(s):  
Baowen Zheng ◽  
R. Marshall Austin ◽  
Xiaoman Liang ◽  
Zaibo Li ◽  
Congde Chen ◽  
...  
Keyword(s):  
Medical Laboratory ◽  
Papanicolaou Test ◽  
Test Methodology ◽  
Glandular Cells ◽  
Atypical Glandular Cells ◽  
International College ◽  
Bethesda System ◽  
Liquid Based Cytology ◽  
The Bethesda System ◽  
Reporting Rates

Context Reports that use the Bethesda System categories for Chinese Papanicolaou test results are rare. Objective To document and analyze rates reported in the Bethesda System for conventional Papanicolaou tests and liquid-based cytology between 2007 and 2012 in China's largest College of American Pathologists–accredited laboratory. Design Results from 1 394 389 Papanicolaou tests, rendered between 2007 and 2012 by the Guangzhou Kingmed Diagnostics Cytology Laboratory, were documented by the Bethesda System report categories and Papanicolaou test methodology, which included both conventional Papanicolaou tests and 4 different liquid-based cytology preparations. Results Results were documented for 326 297 conventional Papanicolaou tests and 1 068 092 liquid-based cytology specimens, which included 928 884 ThinPrep (Hologic, Bedford, Massachusetts), 63 465 SurePath (BD Diagnostics, Franklin Lakes, New Jersey), 50 422 Liqui-Prep (LGM International, Melbourne, Florida), and 25 321 Lituo liquid-cytology (Lituo Biotechnology Co, Hunan, China) specimens. Abnormality rates reported were significantly higher with liquid-based cytology than they were with conventional Papanicolaou tests in all the Bethesda System categories (P < .001). Reporting rates were within the 2006 benchmark ranges from the College of American Pathologists, except for atypical glandular cells (low) and unsatisfactory rates for conventional Papanicolaou tests (low). Conclusion Participation in the international College of American Pathologists Laboratory Accreditation Program provides laboratory quality standards not otherwise available in many international settings.

The utility of pap cell block preparations with liqui-PREP™ cell pellets to clarify the cytological diagnosis of atypical squamous cells of undetermined significance and atypical glandular cells

2017 ◽  
Vol 45 (6) ◽  
pp. 520-525 ◽  
Author(s):  
Nicholas B. George ◽  
Jashua Haddad Baldassari ◽  
Digno A. Pérez Taveras ◽  
María José Fernández ◽  
María Concepción Robledo
Keyword(s):  
Cytological Diagnosis ◽  
Cell Block ◽  
Squamous Cells ◽  
Glandular Cells ◽  
Atypical Glandular Cells ◽  
Undetermined Significance

scholarly journals Human Papillomavirus Testing and Reporting Rates in 2012: Results of a College of American Pathologists National Survey

2014 ◽  
Vol 139 (6) ◽  
pp. 757-761 ◽  
Author(s):  
Chengquan Zhao ◽  
Ann T. Moriarty ◽  
Mohiedean Ghofrani ◽  
Mujtaba Husain ◽  
Rosemary H. Tambouret ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Proficiency Testing ◽  
Hpv Testing ◽  
Papanicolaou Test ◽  
Squamous Cells ◽  
Human Papillomavirus Testing ◽  
Glandular Cells ◽  
Atypical Glandular Cells ◽  
Reflex Testing ◽  
Roche Cobas

Context College of American Pathologists (CAP) surveys are used to establish national benchmarks for laboratory parameters. Objective To evaluate changes in laboratory human papillomavirus (HPV) testing patterns in laboratories incorporating HPV testing with Papanicolaou tests in 2012. Design Data were analyzed from the CAP HPV Supplemental Questionnaire distributed to 1771 laboratories participating in either CAP HPV or CAP Papanicolaou proficiency testing in 2013. Results A total of 1022 laboratories (58%) responded. There were more high-risk (HR) HPV tests performed per institution as compared to previous surveys. There were more HPV tests performed within an institution as compared to previous surveys. Hybrid Capture 2 (HC2) remains the most common method (42.4%, 239 of 564); Cervista and cobas methods are used in 37.2% (210 of 564) and 14.9% (84 of 564) of laboratories, respectively. Human papillomavirus testing is offered as a reflex test after a Papanicolaou test result of atypical squamous cells of undetermined significance (ASC-US) in 89.6% of laboratories (476 of 531); as a cotest for women aged 30 years and older in 60.3% (404 of 531); as reflex testing after atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion (ASC-H) in 42.7% (320 of 531); and as reflex testing after atypical glandular cells (AGC) in 27.3% (145 of 531). The HPV-positive rates for ASC-US and ASC-H were similar in 2012 and 2006. Cervista (49.2%, 88 of 179) and Roche cobas (27.4%, 49 of 179) are the most common methods used for genotyping. Most laboratories use the CAP Human Papillomavirus for Cytology Program for proficiency testing. Conclusions There was an increase in annual volume of HR-HPV testing with a shift toward in-house HR-HPV testing. Genotyping volumes also increased. HC2 and Cervista are most commonly used, with an increasing volume of Roche cobas testing. The most common indication for HPV testing among all laboratories was ASC-US reflex testing, but an increase in HPV cotesting was observed. The data provide an update into persisting and newer trends in HPV testing practices.

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