Neuroendocrine ductal carcinoma in situ of the breast-Case reports-

2011 ◽  
Vol 50 (6) ◽  
pp. 346-350
Author(s):  
Junko KINOSHITA ◽  
Mayuko KAWAHARA ◽  
Eiji SADASHIMA ◽  
Kanako YAMASAKI ◽  
Natsu SADASHIMA ◽  
...  
Keyword(s):  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Case Reports

scholarly journals A rare case of extensive ductal carcinoma in situ of the breast with secretory features

Rare Tumors ◽  
2012 ◽  
Vol 4 (4) ◽  
pp. 169-171 ◽  
Author(s):  
Takanobu Sato ◽  
Akira Iwasaki ◽  
Takeo Iwama ◽  
Shigeo Kawai ◽  
Tsuyoshi Nakagawa ◽  
...  
Keyword(s):  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Rare Case ◽  
Ductal Carcinoma ◽  
Case Reports ◽  
English Literature ◽  
Treatment Plan ◽  
Lymph Node Biopsy ◽  
Japanese Woman

We report a very rare case of extensive ductal carcinoma in situ (DCIS) of the breast with secretory features in a 30-year old Japanese woman. The patient presented with a nodule in the lower inner quadrant of the left breast measuring approximately 2–3 cm, accompanied by an irregular tumor shadow with segmental microcalcification on mammography. These findings suggested malignancy, and excisional biopsy was performed following core needle biopsy. Pathological diagnosis was that of DCIS with secretory features. A treatment plan of simple mastectomy and sentinel lymph node biopsy was chosen. Most previous reports have only described invasive secretory carcinoma of the breast. We have only been able to find 2 case reports of non-invasive secretory lesion in the English literature to date. Because the characteristics of this lesion are not widely known, we thought it important to share our findings.

scholarly journals Croatia’s First Experiences in Cytological Diagnosis of High-Grade Ductal Carcinoma in Situ of the Breast: Case Reports and a Review of Literature

2021 ◽  
Vol 6 (6) ◽  
Keyword(s):  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Case Reports ◽  
Nipple Discharge ◽  
Left Breast ◽  
Cytological Diagnosis ◽  
High Grade ◽  
Morphological Criteria

Cases here presented are also first Croatia’s experiences in the cytological diagnosis of breast ductal carcinoma in situ (DCIS). The first patient was a 64-year-old woman, by imaging methods with a wide area of suspect microcalcifications in the left breast lower medial quadrant and abundant, dense, yellow-greyish discharge of the same mammilla and second was a 65-year-old woman with an equivocal lesion in left breast lower lateral quadrant. Morphological findings of both aspirates and nipple discharge from the first patient were practically the same - moderately to highly cellular, with 3D solid aggregates, monolayer sheets and many scattered single clearly malignant cells of large - mainly >5x the diameter of an erythrocyte, round-to-ovaloid, manifestly irregular nuclei, dark blue, polymorphous, often multiple (macro)nucleoli, irregular nuclear outlines and dense, more basophilic, mostly scant cytoplasms arranged in syncytium–like structures. “Dirty” background was overfull of comedo necrosis and dark grayish, sharp, irregular microcalcifications. Cytological diagnosis in both cases was DCIS, high-grade, comedo type. Histopathologically first tumor was big, 6 cm large, estimated as comedo carcinoma with microinvasion focuses not bigger than 1 mm, but without signs of angioinvasion, while the second tumor was smaller, 0.6 cm with wide ducts fully with large polymorphic malignant epithelial cells, central comedo necrosis, cancerisation of some lobules but with the intact basement membrane. It was pure high-grade DCIS, comedo type. Presented cases completely reflect to date knowledge about cytological diagnostic of high-grade DCIS; include necessary morphological criteria - highgrade nuclear atypia, an abundance of comedo necrosis and microcalcifications, confirm our limitation in the presumption of invasion status with large lesion extent, but also prove that cytology is the unquestionably reliable in breast morphological diagnostic, even in such sophisticated and demanding pathological issue like DCIS.

Sonographic Findings of Ductal Carcinoma in Situ of the Breast: Comparison with Mammographic Findings

1999 ◽  
Vol 41 (6) ◽  
pp. 1225
Author(s):  
Eung Yeop Kim ◽  
Boo Kyung Han ◽  
Yeon Hyeon Choe ◽  
Seok Jin Nam ◽  
Young Hyeh Ko ◽  
...  
Keyword(s):  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma

The Myoepithelium as a Risk Predictor in Ductal Carcinoma In Situ of the Breast

2019 ◽  
Author(s):  
Gemma M Wilson ◽  
Barbara J Guild ◽  
Christine L Clarke ◽  
Nirmala Pathmanathan ◽  
J Dinny Graham
Keyword(s):  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Risk Predictor
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