scholarly journals Diversity myoepithelial cells of salivary gland pleomorphic adenoma-An ultrastructural and immunohistochemical study-

2006 ◽  
Vol 45 (1) ◽  
pp. 43-49
Author(s):  
Taku KATO ◽  
Takashi MATSUMOTO ◽  
Hisao TAKAHASHI ◽  
Miyuki TOKUIZUMI ◽  
Tomoko SUWA ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Immunohistochemical Study ◽  
Myoepithelial Cells

scholarly journals Pleomorphic adenoma of the upper lip: a case report and review of literature

2016 ◽  
Vol 4 (1) ◽  
pp. 8
Author(s):  
Rashmi Metgud ◽  
Bhardwaj Tina Neelesh ◽  
Saurabh Goel ◽  
Smitha Nail ◽  
Shrikant Patel ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Unusual Case ◽  
Needle Aspiration ◽  
Myoepithelial Cells ◽  
Upper Lip ◽  
Epithelial Tumor ◽  
Needle Aspiration Cytology ◽  
Benign Mixed Tumor ◽  
Morphological Patterns

<p>Pleomorphic Adenoma is a benign epithelial tumor arising from the salivary gland. It is a benign mixed tumor composed of epithelial and myoepithelial cells arranged with various morphological patterns, demarcated from surrounding tissues by fibrous capsule. In this article, we report an unusual case of 30 year, male with a single, nodular swelling evident in the upper lip which was discovered during a routine dental procedure. Fine Needle Aspiration Cytology (FNAC) was planned for the patient, where a of cytological diagnosis of Pleomorphic Adenoma was rendered, which was confirmed by biopsy. Hence, this highlights, FNAC makes up an important diagnosing tool as the first line of investigation to distinguish between benign and malignant salivary gland neoplasms.</p>

IMMUNOHISTOCHEMICAL FEATURES OF THE EXPRESSION OF HUMAN PAPILLOMA VIRUS TYPE 16 IN PLEOMORPHIC ADENOMAS OF SALIVARY GLAND

2021 ◽  
Vol 74 (1) ◽  
pp. 7-10
Author(s):  
Igor S. Brodetskyi ◽  
Olena O. Dyadyk ◽  
Vladislav A. Malanchuk ◽  
Mykhailo S. Myroshnychenko ◽  
Mykhailo S. Krotevych
Keyword(s):  
Monoclonal Antibody ◽  
Salivary Gland ◽  
Human Papilloma Virus ◽  
Pleomorphic Adenoma ◽  
Virus Type ◽  
Immunohistochemical Study ◽  
Human Papilloma Virus Type ◽  
Papilloma Virus ◽  
Pleomorphic Adenomas ◽  
Histological Variant

The aim is to reveal the immunohistochemical features of human papilloma virus type 16 expression in various histological variants of pleomorphic adenomas of the salivary gland. Materials and methods: The material of the study was surgical and biopsy material from 30 patients with pleomorphic adenomas of the salivary glands, among which in 15 cases mesenchymal was detected, in 10 – mixed, in 5 cases – epithelial histological variant, respectively. Immunohistochemical study was performed, using mouse monoclonal antibody to human papilloma virus type 16. Visualization was performed, using an EnVisionTM FLEX detection system. Histological sections of grade III cervical intraepithelial neoplasia (CIN III) were used as a positive control; for a negative control, the procedure was performed without primary antibodies. The immunohistochemical reaction was assessed by a semi-quantitative method by counting the percentage of positively stained cells in the field of view of a microscope × 400. Microspecimens were studied, photoarchived on an Olympus BX-41 microscope. Results: Expression of human papilloma virus type 16 of varying severity was determined in 26 cases of pleomorphic adenomas of the salivary glands, which was 86.7%. The epithelial component of the pleomorphic adenoma of the salivary gland was characterized by a more pronounced expression of the monoclonal antibody to human papilloma virus type 16 compared to the mesenchymal component of the tumor. The severity of the immunohistochemical reaction with a monoclonal antibody to human papilloma virus type 16 depended on the histological variant of the pleomorphic adenoma of the salivary gland. Epithelial, mixed and mesenchymal variants of pleomorphic adenoma of the salivary gland were characterized, respectively, by the most pronounced, pronounced and moderately pronounced expression of a monoclonal antibody to human papilloma virus type 16. Conclusions: A comprehensive immunohistochemical study with a monoclonal antibody to human papilloma virus type 16 revealed the presence of a causal relationship between the infection of a patient with human papilloma virus type 16 and development of pleomorphic adenoma of the salivary gland in him.

scholarly journals Morphology of myoepithelial cells seen in pleomorphic adenoma of the salivary gland.

1999 ◽  
Vol 38 (5) ◽  
pp. 403-407 ◽  
Author(s):  
Yuri TAMADA ◽  
Mitsuyoshi HIROKAWA ◽  
Yoshiaki NORIMATSU ◽  
Hiromi KHODA ◽  
Takeshi OKINO ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Myoepithelial Cells
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