scholarly journals Relation between risk factors for uterine endometrial carcinoma and the cellular cluster architecture in endometrial cytology. Focusing on stromal A.

2001 ◽  
Vol 40 (5) ◽  
pp. 445-449
Author(s):  
Shizue HONDA ◽  
Keizo FUJIYOSHI ◽  
Shunichiro OTA ◽  
Kimio USHIJIMA ◽  
Toru SUGIYAMA ◽  
...  
2017 ◽  
Vol 27 (8) ◽  
pp. 1694-1700 ◽  
Author(s):  
Kitty Pavlakis ◽  
Alexandros Rodolakis ◽  
Stylianos Vagios ◽  
Zannis Voulgaris ◽  
Irini Messini ◽  
...  

2021 ◽  
Vol 8 (30) ◽  
pp. 2751-2756
Author(s):  
Jeenu Babu ◽  
Reeba George Pulinilkunnathil ◽  
Bindu R. Kumar

BACKGROUND Endometrial cancer (EC) is also the second most common gynaecologic malignancy in developing countries, with an incidence of 5.9 per 100,000 women. Due to the multiple modifiable factors, a better understanding of the prognostic indicators can lead to early detection and treatment. The purpose of this study was to evaluate the frequency and the distribution of various risk factors, epidemiological factors, and histological patterns of patients diagnosed with endometrial carcinoma in a tertiary teaching hospital in south India and compare them with similar studies. The compiled findings of 60 consecutive cases that presented to our tertiary care teaching hospital in Kerala, south India, over oneand-a-half-year period were studied. METHODS This study was essentially an ex post facto retrospective study done on 60 patients for one and half years. Retrospective data collection and compilation were done with previously prepared structured questionnaires in patients with histologically proven endometrial carcinoma. All cases were subjected to hysterectomy with post-surgical histopathology correlation. A study of the risk factors, general epidemiological characteristics, endometrial biopsy findings, and post-surgical histopathology was done. RESULTS The mean age at presentation was 59.83 years. The mean age of menarche was 13.72 years, and menopause was 49.42 years. The majority of patients were married, multiparous, and presented with bleeding per vaginum (77 %). 61.7 % of the patients had a history of hypertension, 31.7 % had a history of hypothyroidism, and 43.3 % had a history of diabetes mellitus in the study population. The most common histopathological type by endometrial biopsy and histopathological correlation was endometrioid adenocarcinoma (88.3 %). CONCLUSIONS Postmenopausal age group, with early menarche and late menopause, high body mass index (BMI), thickened endometrium on ultrasound, and atrophic uterus were some of the features associated with endometrial carcinoma. The most common histological subtype was found to be endometrioid carcinoma KEYWORDS Endometrial Carcinoma, Risk Factors, Prognostic Indicators


2004 ◽  
Vol 11 (2) ◽  
pp. 305-314 ◽  
Author(s):  
A O Mueck ◽  
H Seeger

Endometrial carcinoma is listed under the absolute contraindications to hormone therapy (HT). According to current opinion, HT after stage I or II is still considered an option, and continuous combined oestrogen/progestogen replacement therapy (CCEPT) would be recommended. However, up to now, only observational studies have been put forward. Although none of these studies have established an increased rate of recurrence or mortality, alternatives such as phytopreparations and tibolone, or particular psychotherapeutic drugs, such as venlafaxine, should be considered for the relief of climacteric complaints. Progestogen-only therapy (PT) particularly has been considered. However, the currently discussed possible progestogen effects regarding an increased risk of breast cancer have to be taken into account. Indeed, the wider discussion about the gestagen effects regarding the risk of breast cancer is to be considered. Generally, after hysterectomy, at least for patients with cardiovascular risk factors, the preference today is to use low-dose oestrogen therapy (patches or gels) instead of CCEPT, and this is also now recommended for patients after endometrial cancer. This is to be noted because of the risk factors for endometrial carcinoma, such as hypertension, obesity, polycystic ovary syndrome (PCO) and diabetes mellitus. However, each form of HT should be only exceptionally recommended, and the patients must be informed about the risks that exist and the use of alternatives.


1985 ◽  
Vol 21 (2) ◽  
pp. 228-234 ◽  
Author(s):  
Zeev Schwartz ◽  
Ram Dgani ◽  
Moshe Y. Flugelman ◽  
Moshe Lancet ◽  
Ilana Gelerenter

2000 ◽  
Vol 39 (5) ◽  
pp. 396-401
Author(s):  
Nobuyoshi OZAWA ◽  
Keiko OTOMO ◽  
Setsuko KAME ◽  
Mieko SATO ◽  
Tsutomu SUZUKA ◽  
...  

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