scholarly journals Voided urine cytology in urothelial cancer of the upper urinary tract - Correlation between histopathologic and cytologic findings, and relationship between exfoliation of neoplastic cells and renal function.

1998 ◽  
Vol 37 (3) ◽  
pp. 279-285
Author(s):  
Fumitaka KOGA ◽  
Toyohiko SATOH ◽  
Hideo SASAKI ◽  
Yoshikatsu HOSOYA ◽  
Hiroshi UMEDA ◽  
...  
Keyword(s):  
Renal Function ◽  
Urinary Tract ◽  
Urothelial Cancer ◽  
Upper Urinary Tract ◽  
Urine Cytology ◽  
Neoplastic Cells

Pathological significance and prognostic utility of KIBRA in upper urinary tract urothelial cancer

2021 ◽  
Vol 79 ◽  
pp. S1087
Author(s):  
T. Kondo ◽  
Y. Miyata ◽  
T. Matsuda ◽  
J. Harada ◽  
Y. Mukae ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Urothelial Cancer ◽  
Upper Urinary Tract ◽  
Prognostic Utility

The Prognostic Value of E-Cadherin, α-, β-, and γ-Catenin in Urothelial Cancer of the Upper Urinary Tract

2006 ◽  
Vol 49 (5) ◽  
pp. 839-845 ◽  
Author(s):  
Keishi Kashibuchi ◽  
Kyoichi Tomita ◽  
Jack A. Schalken ◽  
Haruki Kume ◽  
Takuhiro Yamaguchi ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Prognostic Value ◽  
Urothelial Cancer ◽  
Upper Urinary Tract ◽  
E Cadherin

scholarly journals Predictive Value of Preoperative Positive Urine Cytology for Development of Bladder Cancer After Nephroureterectomy in Patients With Upper Urinary Tract Urothelial Carcinoma: A Prognostic Nomogram Based on a Retrospective Multicenter Cohort Study and Systematic Meta-Analysis

2021 ◽  
Vol 11 ◽  
Author(s):  
Bo Fan ◽  
Yuanbin Huang ◽  
Shuang Wen ◽  
Qiliang Teng ◽  
Xinrui Yang ◽  
...  
Keyword(s):  
Cohort Study ◽  
Urinary Tract ◽  
Meta Analysis ◽  
Upper Urinary Tract ◽  
Urine Cytology ◽  
Biological Behavior ◽  
Recurrence Free Survival ◽  
Free Survival ◽  
Positive Urine ◽  
Urinary Tract Urothelial Carcinoma

BackgroundUpper urinary tract urothelial carcinoma (UUT-UC) is a rare and severe urinary malignancy. Several studies have explored the relationship between preoperative urine cytology and intravesical recurrence (IVR) in patients with UUT-UC. However, the results of these studies are controversial or even contradictory, and investigations with UUT-UC patients in northeast China are rare.MethodsWe first estimated the prognostic significance of preoperative urine cytology in the outcomes of intravesical recurrence in 231 UUT-UC patients (training cohort = 142, validation cohort = 89) after radical nephroureterectomy (RNU) by the nomogram model. Subsequently, we quantitatively combined our results with the published data after searching several databases to assess whether preoperative positive urine cytology was associated with poor intravesical recurrence-free survival and a high risk of tumor malignant biological behavior.ResultsFirstly, the multicenter retrospective cohort study demonstrated that preoperative positive urine cytology correlated with poor intravesical recurrence-free survival and can serve as significant independent predictors of IVR by Kaplan–Meier curves and Cox regression analysis. The construction of the nomogram demonstrated that predictive efficacy and accuracy were significantly improved when preoperative urine cytology was combined. Meanwhile, meta-analysis showed that preoperative positive urine cytology was associated with a 49% increased risk of IVR. In the subgroup analysis by region, study type, and sample size, the pooled hazard ratios (HRs) were statistically significant for the Japan subgroup (HR 1.32), China subgroup (HR 1.88), cohort study subgroup (HR 1.45), and the single-arm study subgroup (HR 1.63).ConclusionsPreoperative urine cytology was validated as a potential predictor of intravesical recurrence in patients with UUT-UC after RNU, although these results need to be generalized with caution. Large, prospective trials are required to further confirm its significance in prognosis and tumor malignant biological behavior.

Neoadjuvant Chemotherapy for Locally Advanced Urothelial Cancer of the Upper Urinary Tract

1995 ◽  
Vol 55 (2) ◽  
pp. 74-77 ◽  
Author(s):  
M. Igawa ◽  
S. Urakami ◽  
H. Shiina ◽  
H. Kishi ◽  
Y. Himeno ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Neoadjuvant Chemotherapy ◽  
Urothelial Cancer ◽  
Locally Advanced ◽  
Upper Urinary Tract ◽  
Advanced Urothelial Cancer
Sign in / Sign up

Export Citation Format

Share Document