scholarly journals Myths: Barriers to Fighting the COVID-19 Pandemic

2021 ◽  
Author(s):  
Olabode Omotoso ◽  
Teibo John ◽  
Gbenga Ojo
Keyword(s):  
The Elderly ◽  
Disease Outbreak ◽  
Human Interaction ◽  
World Population ◽  
The Novel ◽  
Conspiracy Theories ◽  
What Works ◽  
The World ◽  
The Common ◽  
Novel Coronavirus

Myths are widely dispersed but false ideologies or misconceptions. With the thousands of deaths recorded daily and the negative toll of the novel coronavirus disease (COVID-19) on public health, national economy, and human interaction, it remains surprising how people are still being swayed by conspiracy theories. Due to the novelty of the disease, the quest for an answer, what works, and what does not work gave room for the propagation of misinformation, especially on social media. Identifying and debunking myths is very important in managing disease outbreak, since myths can negatively influence the response of people to preventive and containment strategies. Major proponents of COVID-19 myths have promoted their falsehood on the guise that it is a biological weapon engineered to control the world population. Others have also falsely claimed the use of antibiotics or other antiviral drugs in the treatment of COVID-19 and that COVID-19 is no worse than the common flu or it is just the disease of the elderly. This has promoted refusal to take up the COVID-19 vaccine and increased non-adherence to the preventive guidelines. Myths have been a major stumbling block to curtailing the menace of COVID-19. All hands must be on deck to fight this.

scholarly journals Epidemiological Characteristics of COVID-19 in Mexico and the Potential Impact of Lifting Confinement Across Regions

2020 ◽  
Vol 8 ◽  
Author(s):  
Cristy Leonor Azanza Ricardo ◽  
Esteban A. Hernandez-Vargas
Keyword(s):  
The Elderly ◽  
The Novel ◽  
Major Threat ◽  
Large Fluctuations ◽  
The World ◽  
High Death ◽  
Mexican Government ◽  
Potential Impact ◽  
Novel Coronavirus ◽  
Epidemiological Characteristics

The novel coronavirus SARS-CoV-2 has paralyzed our societies, leading to self-isolation and quarantine for several days. As the 10th most populated country in the world, Mexico is on a major threat by COVID-19 due to the limitations of intensive care capacities, about 1.5 hospital beds for every 1,000 citizens. In this paper, we characterize the COVID-19 pandemic in Mexico and projected different scenarios to evaluate sharp or gradual quarantine lifting strategies. Mexican government relaxed strict social distancing regulations on June 1, 2020, deriving to pandemic data with large fluctuations and uncertainties of the tendency of the pandemic in Mexico. Our results suggest that lifting social confinement must be gradually sparse while maintaining a decentralized region strategy among the Mexican states. To substantially lower the number of infections, simulations highlight that a fraction of the population that represents the elderly should remain in social confinement (approximately 11.3% of the population); a fraction of the population that represents the confined working class (roughly 27% of the population) must gradually return in at least four parts in consecutive months; and to the last a fraction of the population that assumes the return of students to schools (about 21.7%). As the epidemic progresses, deconfinement strategies need to be continuously re-adjusting with the new pandemic data. All mathematical models, including ours, are only a possibility of many of the future, however, the different scenarios that were developed here highlight that a gradual decentralized region deconfinement with a significant increase in healthcare capacities is paramount to avoid a high death toll in Mexico.

scholarly journals The Covid-19 Pandemic and its Effect on the Elderly: A Review

2020 ◽  
Vol 5 (3) ◽  
Author(s):  
Maimoona Nadri ◽  
Ujala Zubair
Keyword(s):  
The Elderly ◽  
Medical Community ◽  
Health Concern ◽  
The Novel ◽  
Global Public Health ◽  
Public Health Concern ◽  
The World ◽  
Long Term Consequences ◽  
Novel Coronavirus

In 2019, the world experienced a global public health concern when the novel coronavirus originated from China and affected around fifty-seven thousand people around the world by March 2020. The quick rise in the number of cases and the death toll overwhelmed the scientific and medical community. While all the focus was driven towards finding the epidemiology, the treatment and the management, the mental health aspect of the quarantine was being overlooked. The purpose of this review is to create awareness about the long-term consequences of quarantine, with the focus on the elderly community in Pakistan. 

scholarly journals Obstructive Sleep Apnea and COVID-19 Infection Comorbidity: Analysis of the Problem in the Age Aspect

2020 ◽  
Vol 10 (4) ◽  
pp. 312-315
Author(s):  
Olga Berdina ◽  
Irina Madaeva ◽  
Liubov Rychkova
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Mutual Influence ◽  
The Elderly ◽  
Adverse Outcomes ◽  
The Novel ◽  
Obstructive Sleep ◽  
The Common ◽  
Novel Coronavirus ◽  
The Impact

In the literature, there are suggestions of a possible mutual influence between obstructive sleep apnea (OSA) and the novel coronavirus disease 2019 (COVID-19). The aim of this review is to analyze data found in the literature related to pathogenetic aspects of the impact of OSA on COVID-19, and vice versa, and features of the course of this comorbidity in both adulthood and childhood. Information was searched in MEDLINE, PubMed, EBSCO, and RSCI databases, which presented some data for the connection between COVID-19 and OSA, as well as aspects of OSA and COVID-19 comorbidity for adults and the elderly. The common pathophysiological pathways leading to increased systemic inflammation and adverse consequences of OSA and COVID-19 infection do coexist and were revealed in detail. We paid special attention to aspects of this comorbidity in children and found that research in this area was lacking. Based on this information, it should be concluded that: 1) more pediatric studies of links between OSA and COVID-19 are urgently needed; 2) screening hospitalized COVID-19 patients with tools to detect OSA could identify those at risk for a severe course of these diseases and adverse outcomes; 3) treating OSA will allow increasing the likelihood of developing a robust and long-lasting post-COVID-19 adaptive immunity in these patients.

scholarly journals Common sage (Salvia officinalis) antiviral role: potentiality of a Unani hand sanitizer in COVID-19 (corona virus) second wave control

2021 ◽  
Vol 6 (4) ◽  
pp. 611-617
Author(s):  
MA Momith Azad ◽  
Abdullah Al Mahmud ◽  
Md Shahidul Islam ◽  
Ahmed Iqbal Gouhar
Keyword(s):  
Salvia Officinalis ◽  
Personal Hygiene ◽  
World Population ◽  
The Novel ◽  
Unani Medicine ◽  
Hand Sanitizer ◽  
The World ◽  
Novel Coronavirus ◽  
Second Wave ◽  
Chemical Mixing

The world has been fighting against a pandemic for more than a year, caused by a highly infectious disease named COVID-19 rooted by the novel coronavirus 2019. It has already been spread out in most of the countries and a few of which are experiencing second wave. The Novel coronavirus-2019 (SARS CoV-2) incurred more than 1.6 million deaths and 76 million cases in the world population (till 20 December 2020). Although some vaccines are being launched, however, their effectivity and availability are still unknown. Maintaining personal hygiene and social distance are the best way of protection. Hand washing is the utmost recommendation for the maintenance of personal hygiene since hands can be contaminated by the droplets easily. Particularly, in pandemic situations, it is crucial to interrupt the transmission chain of the virus by the practice of proper hand sanitization. The hand sanitization solely depends on the use of effective hand disinfecting agents. Natural formula-based disinfectants can be preferable to chemicals because of higher efficacy and lower adverse effects. Unani medicine is the system based on natural formulations. „Raihan‟ (common sage, Salvia officinalis) is frequently used in Unani medicine for its higher disinfectant role. Common sage extract with ethanol may provide superior efficacy against COVID-19. In this article, we presented information on common sage and its potentiality using with ethanol as a natural, skin-friendly hand sanitizer to prevent harmful action of chemical mixing synthetic sanitizer. Asian J. Med. Biol. Res. December 2020, 6(4): 611-617

scholarly journals SARS-CoV-2 - Understanding for the Preparation of Forthcoming Corona Virus Outbursts

2020 ◽  
pp. 46-55
Keyword(s):  
Virus Disease ◽  
Deep Understanding ◽  
Disease Outbreak ◽  
International Committee ◽  
Technological Advance ◽  
The Novel ◽  
Corona Virus ◽  
The World ◽  
Novel Coronavirus

A new major epidemic foci of corona virus disease 2019 known as COVID-19, previously known as 2019-nCoV have been identified and rapidly expanding throughout the world without traceable origin since early 2020. The disease has drastically increased and the affected number of countries, states or territories reporting infection to WHO was more than 2001. The 2019 novel corona virus disease outbreak was instigated from Wuhan, Hubei province, China at late December 2019 and affirmed as a public health threat emerging of International anxiety on 30th January 2020 by WHO2. International Committee on Taxonomy of Viruses (ICTV) declared “Severe Acute Respiratory Syndrome Corona Virus (SARS-CoV2)” as the name of novel corona virus, because their genetically similarities with SARS outbreak in 2003. The present review focuses on morphological, genetical characterization of SARS – CoV – 2 as well as the clinical traits and clinical therapies for COVID – 19 endemic up to date. The novel coronavirus emergence awaken the echoes of SARS-CoV pandemic in past decades. Yet, with having best technological advance, the exact medication is still a question. It might be a great lesson to the world to equip to deal with most recent emergent viruses in future. The current work will give a deep understanding of CoV -2 to researcher for the further studies.

scholarly journals COVID-19 AND TOURISM

2021 ◽  
Vol 9 (4) ◽  
pp. 788-804
Author(s):  
Mehtab Alam ◽  
◽  
Rizwana Parveen ◽  
Keyword(s):  
World Economy ◽  
First Aid ◽  
International Travel ◽  
World Population ◽  
The Novel ◽  
Wild Fire ◽  
The World ◽  
To Come ◽  
Novel Coronavirus ◽  
Entire Planet

With the outbreak of the novel coronavirus (COVID-19), the whole world has been in a total shutdown. It came out as a challenge to just not some specific countries of continents, but to the entire planet. With no preparation for such type of pandemic and the time and effort required to come up with a fully functional and tested vaccine, the planet went down on its knees. Non pharmaceutical methods were the first aid for the outbreak. Unprecedented country wide lockdowns, stay at home decisions, closure of global as well as local travel, closure of public gatherings greatly disrupted the world economy. International travel bans were the first to be practiced which roughly affected 100% of the world population. With restrictions on public gatherings and movement of people, tourism came to a stand-still in March-April 2020. By this time, COVID-19 had reached most of the countries and the virus was spreading like wild fire.

scholarly journals Mesenchymal Stromal Cell Secretome for Severe COVID-19 Infections: Premises for the Therapeutic Use

Cells ◽  
2020 ◽  
Vol 9 (4) ◽  
pp. 924 ◽  
Author(s):  
Elia Bari ◽  
Ilaria Ferrarotti ◽  
Laura Saracino ◽  
Sara Perteghella ◽  
Maria Luisa Torre ◽  
...  
Keyword(s):  
Mesenchymal Stromal Cell ◽  
Stromal Cell ◽  
Antiviral Treatment ◽  
Therapeutic Strategies ◽  
World Population ◽  
The Novel ◽  
Pharmacological Effects ◽  
The World ◽  
The Moment ◽  
Novel Coronavirus

From the end of 2019, the world population has been faced the spread of the novel coronavirus SARS-CoV-2 responsible for COVID-19 infection. In approximately 14% of the patients affected by the novel coronavirus, the infection progresses with the development of pneumonia that requires mechanical ventilation. At the moment, there is no specific antiviral treatment recommended for the COVID-19 pandemic and the therapeutic strategies to deal with the infection are only supportive. In our opinion, mesenchymal stem cell secretome could offer a new therapeutic approach in treating COVID-19 pneumonia, due to the broad pharmacological effects it shows, including anti-inflammatory, immunomodulatory, regenerative, pro-angiogenic and anti-fibrotic properties.

scholarly journals The Risk of Lifting COVID-19 Confinement in Mexico

2020 ◽  
Author(s):  
Cristy Leonor Azanza Ricardo ◽  
Esteban A. Hernandez-Vargas
Keyword(s):  
Fold Increase ◽  
The Elderly ◽  
The Novel ◽  
Bed Occupancy ◽  
Major Threat ◽  
Hypothetical Scenario ◽  
The World ◽  
High Death ◽  
Mexican Government ◽  
Novel Coronavirus

ABSTRACTThe novel coronavirus SARS-CoV-2 has paralysed our societies, leading to self isolation and quarantine for several days. As the 10th most populated country in the world, Mexico is on a major threat by COVID-19 due to the limitations of intensive care capacities, and a total of about 1.5 hospital beds for every 1000 citizens. In this paper, we projected different scenarios to evaluate sharp or gradual quarantine lifting strategies, however, even in the hypothetical scenario that Mexico would continue with full confinement, hospitals would be reaching the maximum capacity of hospital bed occupancy. Mexican government is planning to relax the strict social distancing regulations on 1 June 2020, however, epidemic rebound risks are latent.Our results suggest that lifting social confinement needs to be gradually sparse while maintaining a decentralized region strategy among the Mexican states. To substantially lower the number of infections, predictions highlight that the elderly should remain in social confinement (approximately 11.3% of the population); the confined working class (roughly 27% of the population) must gradually return in at least four parts in consecutive months; and to the last the return of students to schools (about 21.7%). As the epidemic progresses, de-confinement strategies need to be continuously re-adjusting with the new pandemic data. Assuming the most optimistic scenario by our predictions, the smallest number of new COVID-19 cases, Mexico would require at least a 3 fold increase in hospital capacities dedicated for COVID-19. Furthermore, to observe the real dimension of the epidemic, Mexico would need to increase to at least 18 samples per 1000 people, currently is only 0.6 per 1000.All mathematical models, including ours, are only a possibility of many of the future, however, the different scenarios that were developed here highlight that a gradual decentralized region de-confinement with a significant increase in healthcare capacities is paramount to avoid a high death toll in Mexico.

scholarly journals Modeling Behavioural Evolution as Social Predictor for the Coronavirus Contagion and Immunization in Nigeria

2020 ◽  
Vol 3 (2) ◽  
pp. 135-144
Author(s):  
Arnold Adimabua Ojugo ◽  
Andrew Okonji Eboka
Keyword(s):  
United States Of America ◽  
The United States ◽  
Health Conditions ◽  
World Population ◽  
The Novel ◽  
Death Toll ◽  
The Social ◽  
The World ◽  
The Rich ◽  
Novel Coronavirus

Since the outbreak of the novel coronavirus (covid-19) pandemic from China in 2019, it has left the world leaders in great confusing due to its fast-paced propagation and spread that has left infected a world population of over Eleven Million persons with over five hundred and thirty four thousand deaths and counting with the United States of America, Brazil, Russia, India and Peru in the lead on these death toll. The pandemic whose increased mortality rate is targeted at ‘aged’ citizens, patients with low immunology as well as patients with chronic diseases and underlying health conditions. Study models covid-19 pandemic via a susceptible-infect-remove actor-based graph, with covid-19 virus as the innovation diffused within the social graph. We measure the rich connective patterns of the actor-based graph, and explore personal feats as they influence other nodes to adopt or reject an innovation. Results shows current triggers (lifting of inter-intra state migration bans) and shocks (exposure to covid-19 by migrants) will lead to late widespread majority adoption of 23.8-percent. At this, the death toll will climb from between 4.43-to-5.61-percent to over 12%.

Comparative docking of SARS-CoV-2 receptors antagonists from repurposing drugs

2020 ◽  
Author(s):  
Micael Davi Lima de Oliveira ◽  
Kelson Mota Teixeira de Oliveira
Keyword(s):  
World Health Organisation ◽  
World Health ◽  
Lung Cells ◽  
The Novel ◽  
High Modulation ◽  
Main Protease ◽  
The World ◽  
Novel Coronavirus ◽  
Viral Receptors ◽  
Theoretical Results

According to the World Health Organisation, until 16 June, 2020, the number of confirmed and notified cases of COVID-19 has already exceeded 7.9 million with approximately 434 thousand deaths worldwide. This research aimed to find repurposing antagonists, that may inhibit the activity of the main protease (Mpro) of the SARS-CoV-2 virus, as well as partially modulate the ACE2 receptors largely found in lung cells, and reduce viral replication by inhibiting Nsp12 RNA polymerase. Docking molecular simulations were performed among a total of 60 structures, most of all, published in the literature against the novel coronavirus. The theoretical results indicated that, in comparative terms, paritaprevir, ivermectin, ledipasvir, and simeprevir, are among the most theoretical promising drugs in remission of symptoms from the disease. Furthermore, also corroborate indinavir to the high modulation in viral receptors. The second group of promising drugs includes remdesivir and azithromycin. The repurposing drugs HCQ and chloroquine were not effective in comparative terms to other drugs, as monotherapies, against SARS-CoV-2 infection.

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