scholarly journals Diagnosis, Prognosis, Management, Treatment, Research and Advances in Canine Dilated Cardiomyopathy

2021 ◽  
Author(s):  
Siobhan Simpson ◽  
Kara-Zoë Kordtomeikel ◽  
Serena Wong ◽  
Samantha Bennison ◽  
Samir A.A. El-Gendy ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Dilated Cardiomyopathy ◽  
Systolic Dysfunction ◽  
Clinical Practices ◽  
Canine Population ◽  
Prevention And Treatment ◽  
Diagnosis Rate ◽  
Treatment Research ◽  
Canine Dilated Cardiomyopathy

Dilated cardiomyopathy involves enlargement of the ventricular chamber and systolic dysfunction. The reduction in quality of life and increased levels of congestive heart failure, combined with the high diagnosis rate within the canine population, highlights the need for research into this disorder. This chapter looks at prevention, diagnosis, prognosis, and treatment of dilated cardiomyopathy. It details the disease pathology and physiology through to present clinical practices and studies to support prevention and treatment. This chapter also looks at the research being undertaken to further understand cardiomyopathies in dogs and develop new interventions. This ranges from fatty acids profiles to genetics and even personalized medicine and comparisons with human cardiomyopathy.

scholarly journals Genital psoriasis: Update on clinical practices and therapeutic options

2021 ◽  
Vol 68 (1) ◽  
pp. 48-51
Author(s):  
Emanuela-Domnica Boieriu ◽  
◽  
Iulia-Elena Negulet ◽  
Ioana-Simona Dinu ◽  
Alexandra-Irina Butacu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Life Quality ◽  
Clinical Findings ◽  
Therapeutic Options ◽  
Topical Steroids ◽  
Clinical Practices ◽  
Clinical Variants ◽  
Genital Psoriasis ◽  
Chronic Skin

Psoriasis is a chronic skin disease with an important inflammatory compound which associates a worldwide prevalence of 0.5% to 8.5%. The involvement of the genital region can be associated with both plaque psoriasis and inverse psoriasis and survey-based studies indicate that up to 45.5% of patients present lesions of genital psoriasis. Genital psoriasis represents a frequent encounter of psoriasis which is often overlooked and which associates a significant impact on their quality of life, measured by Dermatology Life Quality Index (DLQI) scores which are twice as high as those of psoriatic patients without genital involvement. Recognising the specific clinical findings represents an important step in establishing the diagnosis and case management. Classical therapeutic options such as topical steroids or modern treatments such as ixekizumab represent important tools in fighting this affliction and regaining the patient’s quality of life. This review aims to emphasize the up-to-date clinical variants of genital psoriasis, the consequences on the quality of life of patients and to present the newest therapeutic options.

Management of Aromatase Inhibitor–Induced Musculoskeletal Symptoms

2020 ◽  
Vol 16 (11) ◽  
pp. 733-739 ◽  
Author(s):  
Arjun Gupta ◽  
N. Lynn Henry ◽  
Charles L. Loprinzi
Keyword(s):  
Quality Of Life ◽  
Aromatase Inhibitor ◽  
Inhibitor Therapy ◽  
Musculoskeletal Symptoms ◽  
Evidence Based ◽  
Distinct Entity ◽  
Aromatase Inhibitor Therapy ◽  
Prevention And Treatment

Aromatase inhibitor–induced musculoskeletal symptoms (AIMSS) were first recognized as a distinct entity in 2001, 5 years after the approval of the first aromatase inhibitor, anastrozole. Musculoskeletal symptoms can severely affect patients’ quality of life and also lead to premature discontinuation of aromatase inhibitor therapy. Several interventions for managing AIMSS have been investigated in the last decade, with some demonstrating promise. This article provides an evidence-based summary to guide practicing oncologists in regard to the epidemiology, prevention, and treatment of AIMSS.

Evaluation of add on effect of carvedilol on standard protocol of digoxin, frusemide and benazepril in the management of dilated cardiomyopathy in dogs

2018 ◽  
Author(s):  
Akhilesh Kumar ◽  
Sahadeb Dey ◽  
Abhishek Chandra Saxena ◽  
Sumit Mahajan
Keyword(s):  
Quality Of Life ◽  
Cardiac Function ◽  
Dilated Cardiomyopathy ◽  
Standard Therapy ◽  
Ace Inhibitor ◽  
Systolic Function ◽  
Serum Levels ◽  
Post Treatment ◽  
Beneficial Effects

This is a prospective, controlled, randomized clinical trial in canine patients with overt Dilated Cardiomyopathy (DCM). We hypothesized that the addition of the third generation beta-blocker carvedilol to the standard treatment of diuretic (furosemide), inotropic support (digoxin) and ACE-inhibitor (benazepril) would have beneficial effects over cardiac function and quality of life (QoL) that would be measurable 90 days post-treatment. 16 dogs diagnosed with overt DCM were recruited. They underwent clinical examination, electrocardiography, echocardiography and neurohormonal profiling (NT-proBNP and NO). Dogs were divided in two groups, receiving standard therapy or standard therapy plus carvedilol and subjected to re-evaluation on 90 days post-treatment. Our results indicated that the addition of carvedilol to the standard therapy improved echocardiographic indices of systolic function (FS and EF), reduced NT-proBNP and NO serum levels and quality of life within the group but did not showed the significant improvement over standard therapy. This suggested that the addition of carvedilol to the standard therapy in canine patients with overt DCM might have beneficial effects in cardiac function and quality of life in the treatment was continued for longer period.

scholarly journals Overweight dogs are more likely to display undesirable behaviours: results of a large online survey of dog owners in the UK

2017 ◽  
Vol 6 ◽  
Author(s):  
Alexander J. German ◽  
Emily Blackwell ◽  
Mark Evans ◽  
Carri Westgarth
Keyword(s):  
Quality Of Life ◽  
Online Survey ◽  
Behavioural Disorders ◽  
Exact Test ◽  
Pet Dogs ◽  
Overweight Status ◽  
Canine Population ◽  
Television Programme ◽  
The Uk

AbstractMuch of the global canine population is now overweight, and this can adversely affect health, lifespan and quality of life. Undesirable behaviours are also common in pet dogs, and these can adversely affect welfare, as well as being stressful to owners. However, links between obesity and behavioural disorders have never previously been explored. An online survey was conducted between June and August in 2014, coinciding with the broadcast of a National UK television programme, exploring dog health, welfare and behaviour. Information gathered included signalment, overweight status and the prevalence of a range of undesirable behaviours. Fisher's exact test and OR were used to determine associations between overweight status and owner-reported behaviours. A total of 17 028 responses were received. After data verification, the final dataset comprised 11 154 dogs, 1801 (16·1 %) of which were reported by owners to be overweight. Owners of overweight dogs were more likely to see them as ‘a baby’ (P < 0·0001) and allow them to sleep on their bed (P < 0·0001). Overweight dogs were also more likely to guard food (P < 0·0001) and steal food (P < 0·0001). Other undesirable behaviours more commonly reported in overweight dogs included barking, growling or snapping at strangers (P = 0·0011) and other dogs (P = 0·0015), being fearful of outdoors (P < 0·0001), and not always coming back when called (P = 0·0011). Finally, owners were more likely to report that unsociable behaviours adversely affected their dog's health (P < 0·0001). Overweight status is associated with a number of undesirable behaviours in dogs. Further studies are now required to explore the reasons for these associations.

Prognostic relevance of heart rate at rest for survival and the quality of life in patients with dilated cardiomyopathy

2012 ◽  
Vol 101 (9) ◽  
pp. 701-707 ◽  
Author(s):  
Buntaro Fujita ◽  
Marcus Franz ◽  
Bjoern Goebel ◽  
Michael Fritzenwanger ◽  
Hans R. Figulla ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Heart Rate ◽  
Dilated Cardiomyopathy ◽  
Prognostic Relevance

scholarly journals The Progress of the General Prevention and Treatment of Pediatric Caries in China

2019 ◽  
Vol 2 (2) ◽  
pp. 34
Author(s):  
Jinping Liu
Keyword(s):  
Quality Of Life ◽  
Oral Cavity ◽  
Human Health ◽  
Growth And Development ◽  
Critical Period ◽  
Alveolar Bone ◽  
Life Safety ◽  
Prevention And Treatment ◽  
Healthy Growth

At present, caries has become one of the diseases that threaten peoples' health. Because caries usually does not affect patients' life safety, it is not paid enough attention to. In fact, the harm of caries to human health is significant. Caries can cause damage, defect or loss of teeth in the oral cavity. And it may seriously affect the quality of life and health of patients. Especially for children, they are in a critical period of growth and development. Caries may cause pain, lead to inflammation of alveolar bone and jawbone. The development of the dental system will be affected, and even lead to deformity. The prevalence of caries is high in children. Therefore, general prevention and treatment of caries is of great significance to the healthy growth of children

scholarly journals Toward Community Control of Child Welfare Funding

2021 ◽  
Vol 11 (3) ◽  
Author(s):  
Angela Olivia Burton ◽  
Angeline Montauban
Keyword(s):  
Quality Of Life ◽  
New York ◽  
Child Protection ◽  
Child Protective Services ◽  
Black Families ◽  
Child Abuse Prevention ◽  
Community Control ◽  
Protective Services ◽  
Prevention And Treatment

The Child Abuse Prevention and Treatment Act mandates reporting, investigation,and prosecution of allegedly abusive and neglectful parents. Commonly known as child protective services (CPS), this family policing system uses the government’s  police power to disrupt, surveil, control, and destroy hundreds of thousands of Black families based on conditions of poverty framed as neglect. Centering a Black mother’s five-year long ordeal with New York City’s family policing system, we examine the carceral roots of CPS and its destructive impacts on Black families. We call for abolishing the CPS family policing system; diversion of the billions invested in the foster industry to investment in quality-of-life resources de-linked from so-called “child protection”; and monetary reparations for generations of CPS violence against Black families.

Prevention and Treatment of Posttraumatic Stress and Depressive Phenomena in Critical Illness Survivors

2017 ◽  
Author(s):  
Christina Jones ◽  
O. Joseph Bienvenu
Keyword(s):  
Quality Of Life ◽  
Intensive Care ◽  
Critical Illness ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Cost Effective ◽  
Psychological Recovery ◽  
Psychological Therapies ◽  
Prevention And Treatment

Patients recovering from critical illness can be left with significant psychological problems that have a profound effect on their quality of life. As yet, studies on prevention of posttraumatic stress disorder (PTSD) and/or depression are in their infancy. This chapter discusses multimodal rehabilitation strategies that can improve psychological recovery which are beginning to be established. Recognizing those patients needing further help and having a structured pathway for rehabilitation is the first step toward returning patients to as normal a life as possible after critical illness. Providing intensive care unit (ICU) diaries for as many patients as possible is a cost-effective way of helping patients come to terms with their ICU experience. Also discussed in the chapter are psychological therapies, which may be reserved for those survivors of critical illness who are experiencing more severe effects from critical illness and intensive care.

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