scholarly journals Internal and External Radiofrequency Assisted Lipo-Coagulation (RFAL) in the Control of Soft Tissue Contraction during Liposuction: Part 1 “Inside Out” Thermal Tissue Tightening

2021 ◽  
Author(s):  
Robert Stephen Mulholland
Keyword(s):  
Soft Tissue ◽  
Minimally Invasive ◽  
The Body ◽  
Thermal Regulation ◽  
Contact Impedance ◽  
Internal Electrode ◽  
Thermal Coagulation ◽  
Tissue Contraction ◽  
Inside Out ◽  
Positively Charged

Radiofrequency Assisted Lipo-coagulation (RFAL) BodyTite is a contact, impedance, internal and external thermal regulation controlled, internal, minimally invasive, non-excisional procedure providing soft tissue lipo-coagulation and contraction that has been used for over 10 years to optimize skin and soft tissue contraction during liposuction procedures. The device deploys a bipolar applicator inserted into the liposuction zone. The internal, coated, electrode is positively charged and emits a coagulative, ablative injury that results in adipose liquification and Fibroseptal Network (FSN) contraction. The RF flows from the internal electrode after ablation and coagulation up to the external negatively charged return electrode moving on the skin, which heats and tightens the papillary dermis non-ablatively. The body areas that most benefit from this BodyTite technology and procedure include those areas most in need of non-excision contraction include the abdomen, upper arms, inner thighs, bra-line, neck and jaw line. Studies, show, that the combination of BodyTite internal thermal coagulation and external Morpheus8 (see Part 2) at the time of liposuction can result in 40–70% area skin contraction, greatly improving the soft tissue contours and Body shaping outcomes following lipo-contouring procedures.

scholarly journals Internal and External Radiofrequency Assisted Lipo-Coagulation (RFAL) in the Control of Soft Tissue Contraction during Liposuction: Part 2 “Outside In” RFAL Thermal Tissue Tightening

2021 ◽  
Author(s):  
Robert Stephen Mulholland
Keyword(s):  
Soft Tissue ◽  
Invasive Procedure ◽  
Thermal Stimulation ◽  
Thermal Coagulation ◽  
Soft Tissue Envelope ◽  
Non Invasive ◽  
Tissue Contraction ◽  
Contraction Effect ◽  
Positively Charged ◽  
Coated Electrodes

The new Morpheus8 is a novel external RFAL device that uses the proven soft tissue contraction of BodyTite in an external, non-invasive procedure. This external RF applicator, which is also powered by BodyTite, inserts up to 40 positively charged, coated electrodes 8 mm into the subcutaneous, soft tissue envelope. A monopolar ablative lesion is generated from the tip of the electrode, stimulating contraction of the FSN and adipose coagulation. The RF then flows up to the distant negative, return electrodes on the surface of the skin, providing a non-ablative thermal stimulation to the papillary dermis. The “burst” feature of the Morpheus8, delivers simultaneous multiple levels of internal coagulation in a single one second pulse, amplifying the adipose ablation and contraction effect. Studies, show, that the combination of BodyTite internal thermal coagulation and external Morpheus8 at the time of liposuction can result in 60–70% area skin contraction, greatly improving the soft tissue contours and Body shaping outcomes following lipo-contouring procedures.

scholarly journals Monocular tissue reconstruction via remote center motion for robot-assisted minimally invasive surgery

2021 ◽  
Author(s):  
Peng Li ◽  
Ming Tang ◽  
Ke Ding ◽  
Xiaojun Wu ◽  
Yunhui Liu
Keyword(s):  
Minimally Invasive Surgery ◽  
Soft Tissue ◽  
Minimally Invasive ◽  
3D Reconstruction ◽  
Invasive Surgery ◽  
Soft Tissues ◽  
Texture Mapping ◽  
The Body ◽  
Depth Information ◽  
Target Area

AbstractIn minimally invasive surgery, the primary surgeon requires an assistant to hold an endoscope to obtain visual information from the body cavity. However, the two-dimensional images acquired by endoscopy lack depth information. Future automatic robotic surgeries need three-dimensional information of the target area. This paper presents a method to reconstruct a 3D model of soft tissues from image sequences acquired from a robotic camera holder. In this algorithm, a sparse reconstruction module based on the SIFT and SURF features is designed, and a multilevel feature matching strategy is proposed to improve the algorithm efficiency. To recover the realistic effect of the soft-tissue model, a complete 3D reconstruction algorithm is implemented, including densification, meshing of the point cloud and texture mapping reconstruction. During the texture reconstruction stage, a mathematical model is proposed to achieve the repair of texture seams. To verify the feasibility of the proposed method, we use a collaborative manipulator (AUBO i5) with a mounted camera to mimic an assistant surgeon holding an endoscope. To satisfy a pivotal constraint imposed by the remote center of motion (RCM), a kinematic algorithm of the manipulator is implemented, and the primary surgeon is provided with a voice control interface to control the directions of the camera with. We conducted an experiment to show a 3D reconstruction of soft tissue by the proposed method and the manipulator, which indicates that the manipulator works as a robotic assistant which can hold a camera to provide abundant information in the surgery.

scholarly journals Ferromagnetic soft catheter robots for minimally invasive bioprinting

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Cheng Zhou ◽  
Youzhou Yang ◽  
Jiaxin Wang ◽  
Qingyang Wu ◽  
Zhuozhi Gu ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
The Body ◽  
Magnetic Actuation ◽  
Internal Organs ◽  
Planar Surfaces ◽  
Reinforced Polymer ◽  
Direct Fabrication ◽  
Digitally Controlled

AbstractIn vivo bioprinting has recently emerged as a direct fabrication technique to create artificial tissues and medical devices on target sites within the body, enabling advanced clinical strategies. However, existing in vivo bioprinting methods are often limited to applications near the skin or require open surgery for printing on internal organs. Here, we report a ferromagnetic soft catheter robot (FSCR) system capable of in situ computer-controlled bioprinting in a minimally invasive manner based on magnetic actuation. The FSCR is designed by dispersing ferromagnetic particles in a fiber-reinforced polymer matrix. This design results in stable ink extrusion and allows for printing various materials with different rheological properties and functionalities. A superimposed magnetic field drives the FSCR to achieve digitally controlled printing with high accuracy. We demonstrate printing multiple patterns on planar surfaces, and considering the non-planar surface of natural organs, we then develop an in situ printing strategy for curved surfaces and demonstrate minimally invasive in vivo bioprinting of hydrogels in a rat model. Our catheter robot will permit intelligent and minimally invasive bio-fabrication.

scholarly journals Species-Specific Regulation of TRPM2 by PI(4,5)P2 via the Membrane Interfacial Cavity

2021 ◽  
Vol 22 (9) ◽  
pp. 4637
Author(s):  
Daniel Barth ◽  
Andreas Lückhoff ◽  
Frank J. P. Kühn
Keyword(s):  
Amino Acid Residues ◽  
Hek 293 ◽  
Complete Inactivation ◽  
293 Cells ◽  
Activation Mechanisms ◽  
Specific Regulation ◽  
Species Specific ◽  
Inside Out ◽  
Positively Charged

The human apoptosis channel TRPM2 is stimulated by intracellular ADR-ribose and calcium. Recent studies show pronounced species-specific activation mechanisms. Our aim was to analyse the functional effect of phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2), commonly referred to as PIP2, on different TRPM2 orthologues. Moreover, we wished to identify the interaction site between TRPM2 and PIP2. We demonstrate a crucial role of PIP2, in the activation of TRPM2 orthologues of man, zebrafish, and sea anemone. Utilizing inside-out patch clamp recordings of HEK-293 cells transfected with TRPM2, differential effects of PIP2 that were dependent on the species variant became apparent. While depletion of PIP2 via polylysine uniformly caused complete inactivation of TRPM2, restoration of channel activity by artificial PIP2 differed widely. Human TRPM2 was the least sensitive species variant, making it the most susceptible one for regulation by changes in intramembranous PIP2 content. Furthermore, mutations of highly conserved positively charged amino acid residues in the membrane interfacial cavity reduced the PIP2 sensitivity in all three TRPM2 orthologues to varying degrees. We conclude that the membrane interfacial cavity acts as a uniform PIP2 binding site of TRPM2, facilitating channel activation in the presence of ADPR and Ca2+ in a species-specific manner.

scholarly journals Minimally Invasive Autopsy Practice in COVID-19 Cases: Biosafety and Findings

Pathogens ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 412
Author(s):  
Natalia Rakislova ◽  
Lorena Marimon ◽  
Mamudo R. Ismail ◽  
Carla Carrilho ◽  
Fabiola Fernandes ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Cause Of Death ◽  
Diffuse Alveolar Damage ◽  
The Body ◽  
Protective Equipment ◽  
Safe Alternative ◽  
Minimally Invasive Autopsy ◽  
Postmortem Studies ◽  
Death Investigation ◽  
Insight Into

Postmortem studies are crucial for providing insight into emergent diseases. However, a complete autopsy is frequently not feasible in highly transmissible diseases due to biohazard challenges. Minimally invasive autopsy (MIA) is a needle-based approach aimed at collecting samples of key organs without opening the body, which may be a valid alternative in these cases. We aimed to: a) provide biosafety guidelines for conducting MIAs in COVID-19 cases, b) compare the performance of MIA versus complete autopsy, and c) evaluate the safety of the procedure. Between October and December 2020, MIAs were conducted in six deceased patients with PCR-confirmed COVID-19, in a basic autopsy room, with reinforced personal protective equipment. Samples from the lungs and key organs were successfully obtained in all cases. A complete autopsy was performed on the same body immediately after the MIA. The diagnoses of the MIA matched those of the complete autopsy. In four patients, COVID-19 was the main cause of death, being responsible for the different stages of diffuse alveolar damage. No COVID-19 infection was detected in the personnel performing the MIAs or complete autopsies. In conclusion, MIA might be a feasible, adequate and safe alternative for cause of death investigation in COVID-19 cases.

The October 2005 Earthquake in Northern Pakistan: Pattern of Injuries in Victims Brought to the Emergency Relief Hospital, Doraha, Mansehra

2009 ◽  
Vol 24 (6) ◽  
pp. 535-539 ◽  
Author(s):  
Fahad Sami ◽  
Fahad Ali ◽  
Syed Habib Haider Zaidi ◽  
Hiba Rehman ◽  
Tashfeen Ahmad ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Lower Limb ◽  
Soft Tissue Injuries ◽  
The Body ◽  
Northern Pakistan ◽  
Cross Sectional ◽  
Emergency Relief ◽  
Medical Needs ◽  
Bone Injury ◽  
Tissue Injuries

AbstractObjective:Knowledge of injuries of earthquake victims is important to plan relief efforts. This cross-sectional study was conducted following the 08 October 2005 earthquake in Northern Pakistan to determine the pattern of injuries sustained and their relationship with age and gender in order to identify the medical needs in an earthquake-affected zone.Methods:The study was conducted between 13 October and 23 October 2005 at the Emergency Relief Hospital, Doraha, Mansehra. From the 1,700 patients registered in the hospital, 310 were sampled randomly for the study. Demography and details of the patients' injuries were noted by history and physical examination. Twelve cases were omitted due to incomplete data.Results:Of the cases, 54% were female. Children ≤10 years old formed the largest age group. Isolated bone injuries were present in 41%, soft tissue injuries in 36%, and mixed injuries in 23% of the patients.The most common bone injury was lower limb fracture (52%), while the most common non-bone injury was non-infected, soft tissue wounds on the limbs (33%). Among patients with soft tissue injuries, gangrenous wounds were present in 9%, and grossly infected wounds in 30% (20% on limbs and 10% on rest of the body).Conclusions:The population injured during the earthquake showed a higher proportion of females and children ≤10 years old, and lower limb bone injuries. The data highlight the need to address orthopedic, pediatric, and women's health issues, and for logistic arrangement of relevant diagnostic and therapeutic facilities at the initial stages of relief activities after earthquakes.

scholarly journals The role of endogenous opiates in thermal regulation of the body during exercise.

BMJ ◽  
1985 ◽  
Vol 290 (6470) ◽  
pp. 739-740 ◽  
Author(s):  
K De Meirleir ◽  
T Arentz ◽  
W Hollmann ◽  
L Vanhaelst
Keyword(s):  
The Body ◽  
Thermal Regulation ◽  
Endogenous Opiates

The Use a Hernia Mesh to Enable Soft Tissue Reattachment to the Body of a Proximal Femoral Endoprosthesis

2017 ◽  
Vol 32 (2) ◽  
pp. 103 ◽  
Author(s):  
Matthew J. Wilson ◽  
Hussain A. Kazi ◽  
John R. Morley
Keyword(s):  
Soft Tissue ◽  
The Body ◽  
Hernia Mesh

Late Stage Decomposition of Embalmed Cadavers

2021 ◽  
Vol 2 (1) ◽  
Author(s):  
Pilar Mata Tutor ◽  
Catherine Villoria Rojas ◽  
María Benito Sánchez
Keyword(s):  
Soft Tissue ◽  
Late Stage ◽  
Good Condition ◽  
Experimental Studies ◽  
The Body ◽  
Health Law ◽  
External Appearance ◽  
Intrinsic Factors ◽  
Preservation Technique ◽  
Extrinsic And Intrinsic Factors

Decomposition is a natural process that begins approximately four minutes after death and continues until the body is degraded to simpler biochemical components which are gradually recycled back to the environment. This process is dependent on extrinsic and intrinsic factors. Embalming is a chemical preservation technique that aims to preserve the external appearance of the body in good condition for an indeterminate period. In Spain, there is a lack of experimental studies carried out to analyse the variables that affect decomposition in embalmed bodies, therefore, in accordance with the conclusions reached by previous authors, it is hypothesised that embalmed bodies show quantifiable characteristics during the late stage decomposition which distinguish them from control, unembalmed, cadavers. An anthropological and statistical analysis was performed on 14 individuals from Cementerio Sur de Madrid exhumed after ten years according to the Mortuary Health Law of the Autonomous Region of Madrid. The preliminary results obtained showed that there is a qualitative and statistically significant relationship between the variables evaluated, being the presence or absence of soft tissue the most notable difference. The mortuary or thanatopraxy treatments performed before the burial and the microenvironmental conditions of the burial positively influence the soft tissue preservation on embalmed bodies. These results contribute to the understanding about the decomposition rate of an embalmed cadavers in cemeteries, and the related extrinsic variables.

Sign in / Sign up

Export Citation Format

Share Document