scholarly journals Prototyping and Production of Polymeric Microfluidic Chip

2021 ◽  
Author(s):  
Honggang Zhang ◽  
Haoyang Zhang ◽  
Tianyu Guan ◽  
Xiangyu Wang ◽  
Nan Zhang
Keyword(s):  
Microfluidic Chip ◽  
Mass Production ◽  
Microfluidic Chips ◽  
Important Research ◽  
Process Chain ◽  
Future Perspectives ◽  
End User ◽  
Research Findings ◽  
Manufacturing Technologies ◽  
Tooling Technology

Microfluidic chips have found many advanced applications in the areas of life science, analytical chemistry, agro-food analysis, and environmental detection. This chapter focuses on investigating the commonly used manufacturing technologies and process chain for the prototyping and mass production of microfluidic chips. The rapid prototyping technologies comprising of PDMS casting, micro machining, and 3D-printing are firstly detailed with some important research findings. Scaling up the production process chain for microfluidic chips are discussed and summarized with the perspectives of tooling technology, replication, and bonding technologies, where the primary working mechanism, technical advantages and limitations of each process method are presented. Finally, conclusions and future perspectives are given. Overall, this chapter demonstrates how to select the processing materials and methods to meet practical requirements for microfluidic chip batch production. It can provide significant guidance for end-user of microfluidic chip applications.

A Microfluidic Chip Microwave Bonding Method Based on the PMMA

2013 ◽  
Vol 562-565 ◽  
pp. 561-565
Author(s):  
Xiao Wei Liu ◽  
Xiao Wei Han ◽  
He Zhang ◽  
Xi Yun Jiang ◽  
Lin Zhao
Keyword(s):  
Microwave Radiation ◽  
Microfluidic Chip ◽  
Mass Production ◽  
Bonding Strength ◽  
Microfluidic Chips ◽  
Ultrasonic Bonding ◽  
Microwave Absorbing ◽  
Bonding Method ◽  
Bonding Technique

A new bonding technique mainly for PMMA microfluidic chips is presented in this paper. In this technique, polymer microfluidic microchannels were bonded by microwave radiation. Its strength and time can be controlled accurately in watt and second level. There are so many techniques for mass-production of polymer microfluidic chip, such as heat bonding, ultrasonic bonding. However, we may find different kinds of shortages when we use these techniques. In this paper, the experiment result shows that microwave radiation’s strength and time have effects on microfluidic chip`s bonding strength. The microwave absorbing coating can also have a certain degree influence on microfluidic chip`s bonding strength.

Heating Carve Technique for Polymer Microfluidic Microchannel

2012 ◽  
Vol 503 ◽  
pp. 103-107
Author(s):  
Xiao Wei Han ◽  
Wei Wang ◽  
G.H. Ye ◽  
Xiao Wei Liu ◽  
Li Tian ◽  
...  
Keyword(s):  
Polymethyl Methacrylate ◽  
Microfluidic Chip ◽  
Mass Production ◽  
Hot Embossing ◽  
Direct Write ◽  
Microfluidic Chips ◽  
Movement Velocity ◽  
Laser Direct Write

A new manufacture mainly for polymethyl methacrylate (PMMA) microfluidic chips is presented in this paper. In this technique, polymer microfluidic microchannels were fabricated by microcutter which temperature is controlled and stabilized by PID methord. There are so many techniques, such as hot embossing, laser direct-write, for mass-production of polymer microfluidic chip. However, we may feel different kinds of shortages when we use these techniques. In this paper, the experiment result shows that microcutter’s movement velocity and temperature have effert on microfluidic microchannel’s roughness.

Organocatalytic dimensions to the C–H functionalization of the carbocyclic core in indoles: a review update

2021 ◽  
Author(s):  
Prantika Bhattacharjee ◽  
Utpal Bora
Keyword(s):  
Important Research ◽  
Research Findings

A review highlighting important research findings in remote C–H activation processes using effectual organocatalytic perspectives. The challenging indole carbocyclic ring positions were successfully accessed with proper regio- and stereocontrols.

Study on the Manufacture of Microfluidic Chip with Coated Glass

2012 ◽  
Vol 548 ◽  
pp. 254-257 ◽  
Author(s):  
Yan He ◽  
Bai Ling Huang ◽  
Yong Lai Zhang ◽  
Li Gang Niu
Keyword(s):  
Microfluidic Chip ◽  
Low Cost ◽  
Microfluidic Channel ◽  
Critical Factor ◽  
Wet Etching ◽  
Microfluidic Chips ◽  
Etching Technique ◽  
Chip Quality ◽  
Wet Chemical ◽  
Wet Chemical Etching

In this paper, a simple and facile technique for manufacturing glass-based microfluidic chips was developed. Instead of using expensive dry etching technology, the standard UV lithography and wet chemical etching technique was used to fabricate microchannels on a K9 glass substrate. The fabrication process of microfluidic chip including vacuum evaporation, annealing, lithography, and BHF (HF-NH4F-H2O) wet etching were investigated. Through series experiments, we found that anneal was the critical factor for chip quality. As a representative example, a microfluidic channel with 20 m of depth, and 80 m of width was successfully prepared, and the channel surfaces are quite smooth. These results present a simple, low cost, flexible and easy way to fabricate glass-based microfluidic chips.

Systematische Bewertung von FKV-Fertigungstechnologien*/Systematic evaluation of FRP manufacturing technologies - Technology evaluation by the example of large-scale series production of fiber-reinforced plastic (FRP) components

2016 ◽  
Vol 106 (03) ◽  
pp. 125-130
Author(s):  
D. Hofbauer ◽  
J. Greitemann ◽  
M. Grammer ◽  
J. Kaufmann ◽  
G. Prof. Reinhart
Keyword(s):  
Mass Production ◽  
High Performance ◽  
Large Scale ◽  
Systematic Evaluation ◽  
Series Production ◽  
Fiber Reinforced ◽  
Fiber Reinforced Plastic ◽  
Reinforced Plastic ◽  
Plastic Components ◽  
Manufacturing Technologies

Hochleistungswerkstoffe wurden bisher nur für Spezialanwendungen eingesetzt, da hohe Materialkosten und eine geringe Reife der Fertigungstechnologien die Anwendung in der Großserie erschwert haben. Um die grundlegende Eignung der Technologien unter Beachtung der Produktanforderungen zu ermitteln, präsentiert dieser Fachbeitrag eine Methodik für die systematische Bewertung, die am Beispiel der Großserienfertigung von Bauteilen aus Faser-Kunststoff-Verbundwerkstoffen (FKV) erläutert wird.   The use of high-performance materials has so far been limited to special applications for reasons of high material costs and low maturity of manufacturing technologies. These facts avoided their use in mass production in the past. This paper presents a method for systematically evaluating technologies to determine their fundamental suitability for mass production. It is exemplified by large-scale series production of fiber-reinforced plastic components.

scholarly journals Measuring the bore straightness during reaming with sensoric tools

2020 ◽  
Vol 14 (4) ◽  
pp. 535-544
Author(s):  
Andreas Bretz ◽  
Eberhard Abele ◽  
Matthias Weigold
Keyword(s):  
Mass Production ◽  
Cost Efficiency ◽  
Machine Tools ◽  
Processing Time ◽  
Process Chain ◽  
Machining Processes ◽  
High Quality ◽  
Random Samples ◽  
Hydraulic Valves ◽  
Productive Time

Abstract Reaming plays a crucial role in production to meet the high quality requirements of precision bore machining. It is either directly responsible for the final component quality or influences subsequent processes such as honing. The narrow tolerances are usually monitored by measuring random samples in mass production due to cost efficiency. Having a closer look at an exemplary process chain for the production of hydraulic valves shows the possibility to adapt the honing parameters which reduces processing time and costs. However, the bore straightness after the reaming process has to be known. In this paper an approach is presented which allows to record the bore straightness within the productive time. For this purpose, a sensory reaming system is developed. It can be used without additional components in the machine tool and thus integrated into existing machining processes. Cutting tests show that the system is able to measure the bore straightness as good as sensing probes used in machine tools.

scholarly journals Immigrants in polish economy

VUZF Review ◽  
2021 ◽  
Vol 6 (2) ◽  
pp. 233-238
Author(s):  
Iwona Dudzik ◽  
Irena Brukwicka
Keyword(s):  
Immigrant Workers ◽  
Physical Work ◽  
Important Research ◽  
Intention To Stay ◽  
The Past ◽  
Industrial Sectors ◽  
Research Findings ◽  
The Republic ◽  
Polish Economy ◽  
Near Future

This article deals with immigrants in Polish economy. The aim of the article is to present the most important research findings, concerning immigrants and enterprises where they are employed. This issue also includes the influence of the COVID-19 pandemic. The authors of this paper focused mostly on Ukrainian immigrants. It has been proven that increase in the number of immigrant workers leads to the growth of the Gross Domestic Product, and contributes to the faster growth in remittances from the Republic of Poland to Ukraine. As a result of the adverse impact of the COVID-19 pandemic on sales, non-employment costs were reduced in the service and industrial sectors. Employment changes were not correlated with company’s situation.  It is worth noting, that because of the COVID-19 pandemic, some companies may be less inclined to recruit immigrants in the near future, and the overall demand for labor may decrease. This is particularly important, because the primary reason for employment people from abroad was the inability to meet labor needs of the citizens of Poland. The majority of immigrants are employed only to perform physical work which does not require qualifications. Large companies show greater interest in the foreign human capital. Over the past five years, there has been an increase in the number of immigrants who declared their intention to stay in Poland for a longer period of time. More than half of the immigrants stay in Poland, with at least, one family member. On this basis, it may be concluded that the number of immigrants willing to settle in Poland is growing.

Experimental Pragmatics

2015 ◽  
Author(s):  
Raymond W. Gibbs
Keyword(s):  
Common Ground ◽  
Experimental Methods ◽  
Alternative View ◽  
Important Research ◽  
Experimental Pragmatics ◽  
Linguistic Pragmatics ◽  
Conversational Implicatures ◽  
Research Findings ◽  
Discourse Understanding

This chapter describes some of the important research in experimental pragmatics, most notably studies related to recovering speakers’ intentions, inferring conversational implicatures, and the role of common ground in discourse understanding. My aim is to demonstrate the utility of different experimental methods for studying pragmatics, and how research findings in the field are relevant to traditional concerns within the linguistic pragmatics community. But I will also argue that experimental pragmatic studies show great regularities and significant variation, both within and across individuals, in the ways people speak and understand language. My alternative view claims that dynamical, self-organizing processes form the critical background from which meaningful pragmatic actions emerge. The implications of this position for interdisciplinary pragmatic research will be discussed.

scholarly journals Current Research and Future Perspectives on Graphene Synthesis

2020 ◽  
Vol 319 ◽  
pp. 10001
Author(s):  
Cesar H. Ortega-Jimenez ◽  
Rony Omar Flores Urbina ◽  
Roberto Arturo Leiva Castro ◽  
Víctor Moises Matamoros Chavarría ◽  
Tony Rodolfo Oyuela López ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Vapor Deposition ◽  
Mass Production ◽  
Chemical Vapor ◽  
Adhesive Tape ◽  
Synthesis Methods ◽  
Future Perspectives ◽  
Graphene Synthesis ◽  
Industrial Implementation ◽  
Increasing Trend

Although graphitic materials are considered indispensable across many industries, practitioners and researchers have shown that graphene is still in development and its industrial implementation in mass production may save many organizations millions of dollars a year. This paper presents a comprehensive and systematic literature review of graphene synthesis methods. In our research, we noticed an increasing trend in publications for research under diverse scenarios (e.g., engineering, entrepreneurship, academy, etc.), which limits the generalizing of the findings due to the nature of graphene’s synthesis. Most of these studies were conducted about electrical and mechanical properties for possible sector applications due to its structure. We found that less effort has been made to analyse the development and synthesis of methods that allow graphene manufacturing in industrial quantities. We classified the five most important synthesis methods of graphene, categorizing chemical vapor deposition (CVD), and adhesive tape exfoliation as the most implemented methods, with the latter getting better quality and greater quantity of graphene. We also identified needs for research on graphene that goes beyond its known properties, by focusing on models that encompass the innovation needed for manufacturers of materials in areas, such as electronics and energy.

Mathematical Modeling and Fuzzy Analysis of Hot Runner in Comparison to Cold Runner in Injection Moulding

2019 ◽  
Vol 18 (04) ◽  
pp. 657-676
Author(s):  
Sandeep Mathur ◽  
Ravinder Kumar ◽  
Vipul Mathur
Keyword(s):  
Mass Production ◽  
Weight Ratio ◽  
Production Environment ◽  
Slight Improvement ◽  
Decision Making Problem ◽  
Cycle Time Reduction ◽  
Index Value ◽  
Tooling Technology ◽  
Material Utilization ◽  
Insight Into

In a mass production environment of supply chains where volume of production runs into millions of parts per month where even the slight improvement in the manufacturing process through cycle time reduction or better material utilization has the potential to produce huge savings and productivity to match customer tact time, the paper serves a useful insight into appropriate tooling technology for moulding processes. Though there have been several studies on hot runner technology in injection molding processes vis a vis conventional cold runner technology, ultimate manufacturer still has to conduct trials and calculate ROIs, initial investment, quality and maintainability aspect to conclude if the manufacturer can go for hot runner or not. The paper lends a scientific expression to this decision making problem and offers a mathematical model with variables like Gross weight to Net Weight ratio, machine tonnage, volume involved. The user only has to put in the values to get an index value with a threshold number to decide if hot runner is viable for the component in hand or not.

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