scholarly journals An Evolutionary Perspective for Network Centric Therapy through Wearable and Wireless Systems for Reflex, Gait, and Movement Disorder Assessment with Machine Learning

2021 ◽  
Author(s):  
Robert LeMoyne ◽  
Timothy Mastroianni

Wearable and wireless systems have progressively evolved to achieve the capabilities of Network Centric Therapy. Network Centric Therapy comprises the application of wearable and wireless inertial sensors for the quantification of human movement, such as reflex response, gait, and movement disorders, with machine learning classification representing advanced diagnostics. With wireless access to a functional Cloud computing environment Network Centric Therapy enables subjects to be evaluated at any location of choice with Internet connectivity and expert medical post-processing resources situated anywhere in the world. The evolutionary origins leading to the presence of Network Centric Therapy are detailed. With the historical perspective and state of the art presented, future concepts are addressed.

2019 ◽  
Vol 38 (14) ◽  
pp. 1529-1537 ◽  
Author(s):  
Pauline Maurice ◽  
Adrien Malaisé ◽  
Clélie Amiot ◽  
Nicolas Paris ◽  
Guy-Junior Richard ◽  
...  

Improving work conditions in industry is a major challenge that can be addressed with new emerging technologies such as collaborative robots. Machine learning techniques can improve the performance of those robots, by endowing them with a degree of awareness of the human state and ergonomics condition. The availability of appropriate datasets to learn models and test prediction and control algorithms, however, remains an issue. This article presents a dataset of human motions in industry-like activities, fully labeled according to the ergonomics assessment worksheet EAWS, widely used in industries such as car manufacturing. Thirteen participants performed several series of activities, such as screwing and manipulating loads under different conditions, resulting in more than 5 hours of data. The dataset contains the participants’ whole-body kinematics recorded both with wearable inertial sensors and marker-based optical motion capture, finger pressure force, video recordings, and annotations by three independent annotators of the performed action and the adopted posture following the EAWS postural grid. Sensor data are available in different formats to facilitate their reuse. The dataset is intended for use by researchers developing algorithms for classifying, predicting, or evaluating human motion in industrial settings, as well as researchers developing collaborative robotics solutions that aim at improving the workers’ ergonomics. The annotation of the whole dataset following an ergonomics standard makes it valuable for ergonomics-related applications, but we expect its use to be broader in the robotics, machine learning, and human movement communities.


Sensors ◽  
2021 ◽  
Vol 21 (10) ◽  
pp. 3451
Author(s):  
Luca Marotta ◽  
Jaap H. Buurke ◽  
Bert-Jan F. van Beijnum ◽  
Jasper Reenalda

Physical fatigue is a recurrent problem in running that negatively affects performance and leads to an increased risk of being injured. Identification and management of fatigue helps reducing such negative effects, but is presently commonly based on subjective fatigue measurements. Inertial sensors can record movement data continuously, allowing recording for long durations and extensive amounts of data. Here we aimed to assess if inertial measurement units (IMUs) can be used to distinguish between fatigue levels during an outdoor run with a machine learning classification algorithm trained on IMU-derived biomechanical features, and what is the optimal configuration to do so. Eight runners ran 13 laps of 400 m on an athletic track at a constant speed with 8 IMUs attached to their body (feet, tibias, thighs, pelvis, and sternum). Three segments were extracted from the run: laps 2–4 (no fatigue condition, Rating of Perceived Exertion (RPE) = 6.0 ± 0.0); laps 8–10 (mild fatigue condition, RPE = 11.7 ± 2.0); laps 11–13 (heavy fatigue condition, RPE = 14.2 ± 3.0), run directly after a fatiguing protocol (progressive increase of speed until RPE ≥ 16) that followed lap 10. A random forest classification algorithm was trained with selected features from the 400 m moving average of the IMU-derived accelerations, angular velocities, and joint angles. A leave-one-subject-out cross validation was performed to assess the optimal combination of IMU locations to detect fatigue and selected sensor configurations were considered. The left tibia was the most recurrent sensor location, resulting in accuracies ranging between 0.761 (single left tibia location) and 0.905 (all IMU locations). These findings contribute toward a balanced choice between higher accuracy and lower intrusiveness in the development of IMU-based fatigue detection devices in running.


2021 ◽  
Vol 15 ◽  
Author(s):  
Alhassan Alkuhlani ◽  
Walaa Gad ◽  
Mohamed Roushdy ◽  
Abdel-Badeeh M. Salem

Background: Glycosylation is one of the most common post-translation modifications (PTMs) in organism cells. It plays important roles in several biological processes including cell-cell interaction, protein folding, antigen’s recognition, and immune response. In addition, glycosylation is associated with many human diseases such as cancer, diabetes and coronaviruses. The experimental techniques for identifying glycosylation sites are time-consuming, extensive laboratory work, and expensive. Therefore, computational intelligence techniques are becoming very important for glycosylation site prediction. Objective: This paper is a theoretical discussion of the technical aspects of the biotechnological (e.g., using artificial intelligence and machine learning) to digital bioinformatics research and intelligent biocomputing. The computational intelligent techniques have shown efficient results for predicting N-linked, O-linked and C-linked glycosylation sites. In the last two decades, many studies have been conducted for glycosylation site prediction using these techniques. In this paper, we analyze and compare a wide range of intelligent techniques of these studies from multiple aspects. The current challenges and difficulties facing the software developers and knowledge engineers for predicting glycosylation sites are also included. Method: The comparison between these different studies is introduced including many criteria such as databases, feature extraction and selection, machine learning classification methods, evaluation measures and the performance results. Results and conclusions: Many challenges and problems are presented. Consequently, more efforts are needed to get more accurate prediction models for the three basic types of glycosylation sites.


2020 ◽  
Vol 13 (5) ◽  
pp. 508-523 ◽  
Author(s):  
Guan‐Hua Huang ◽  
Chih‐Hsuan Lin ◽  
Yu‐Ren Cai ◽  
Tai‐Been Chen ◽  
Shih‐Yen Hsu ◽  
...  

2021 ◽  
pp. 158-166
Author(s):  
Noah Balestra ◽  
Gaurav Sharma ◽  
Linda M. Riek ◽  
Ania Busza

<b><i>Background:</i></b> Prior studies suggest that participation in rehabilitation exercises improves motor function poststroke; however, studies on optimal exercise dose and timing have been limited by the technical challenge of quantifying exercise activities over multiple days. <b><i>Objectives:</i></b> The objectives of this study were to assess the feasibility of using body-worn sensors to track rehabilitation exercises in the inpatient setting and investigate which recording parameters and data analysis strategies are sufficient for accurately identifying and counting exercise repetitions. <b><i>Methods:</i></b> MC10 BioStampRC® sensors were used to measure accelerometer and gyroscope data from upper extremities of healthy controls (<i>n</i> = 13) and individuals with upper extremity weakness due to recent stroke (<i>n</i> = 13) while the subjects performed 3 preselected arm exercises. Sensor data were then labeled by exercise type and this labeled data set was used to train a machine learning classification algorithm for identifying exercise type. The machine learning algorithm and a peak-finding algorithm were used to count exercise repetitions in non-labeled data sets. <b><i>Results:</i></b> We achieved a repetition counting accuracy of 95.6% overall, and 95.0% in patients with upper extremity weakness due to stroke when using both accelerometer and gyroscope data. Accuracy was decreased when using fewer sensors or using accelerometer data alone. <b><i>Conclusions:</i></b> Our exploratory study suggests that body-worn sensor systems are technically feasible, well tolerated in subjects with recent stroke, and may ultimately be useful for developing a system to measure total exercise “dose” in poststroke patients during clinical rehabilitation or clinical trials.


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