scholarly journals Association of Personal Anxiety with Dopamine Receptor D4 (DRD4), DAT Genes Polymorphism

2020 ◽  
Author(s):  
Valery V. Gafarov ◽  
Elena A. Gromova ◽  
Vladimir N. Maksimov ◽  
Igor V. Gagulin ◽  
Almira V. Gafarova
Keyword(s):  
Personality Traits ◽  
Dopaminergic System ◽  
Individual Variability ◽  
Stress Disorders ◽  
Genetic Trait ◽  
Open Population ◽  
Genes Encoding ◽  
Personal Anxiety ◽  
Dopamine Receptor D4

Modern studies in the world have attached high priority to the role of genetics in human psychosocial stress. People who have strong biochemical responses to stress are more inclined to develop acute and posttraumatic stress disorders. Why do such unusually strong biological reactions occur in certain people? Psychogenetics focuses on many aspects: personality traits that can affect human behavior directly. Their individual variability has been found to be a genetic trait. At present we already know a number of genes, certain allelic variants and genotypes associated with some neuropsychological characters. Among these are genes encoding intracellular and plasma protein neurotransmitter transporters and their receptors; to date, there are only several dozen genes. Of particular interest are dopaminergic system genes. However, information about the polymorphism of known genes associated with personality traits is quite limited and contradictory for open population. Under these circumstances, the chapter is devoted to the association of polymorphisms of candidate genes of the dopaminergic system with anxiety in the open population.

DNA methylation in satellite repeats disorders

2019 ◽  
Vol 63 (6) ◽  
pp. 757-771 ◽  
Author(s):  
Claire Francastel ◽  
Frédérique Magdinier
Keyword(s):  
Dna Methylation ◽  
Human Genome ◽  
Repetitive Dna ◽  
Dna Sequences ◽  
Satellite Repeats ◽  
Tremendous Progress ◽  
Genes Encoding ◽  
Dna Elements ◽  
Near Future

Abstract Despite the tremendous progress made in recent years in assembling the human genome, tandemly repeated DNA elements remain poorly characterized. These sequences account for the vast majority of methylated sites in the human genome and their methylated state is necessary for this repetitive DNA to function properly and to maintain genome integrity. Furthermore, recent advances highlight the emerging role of these sequences in regulating the functions of the human genome and its variability during evolution, among individuals, or in disease susceptibility. In addition, a number of inherited rare diseases are directly linked to the alteration of some of these repetitive DNA sequences, either through changes in the organization or size of the tandem repeat arrays or through mutations in genes encoding chromatin modifiers involved in the epigenetic regulation of these elements. Although largely overlooked so far in the functional annotation of the human genome, satellite elements play key roles in its architectural and topological organization. This includes functions as boundary elements delimitating functional domains or assembly of repressive nuclear compartments, with local or distal impact on gene expression. Thus, the consideration of satellite repeats organization and their associated epigenetic landmarks, including DNA methylation (DNAme), will become unavoidable in the near future to fully decipher human phenotypes and associated diseases.

Role of Coping and Personality Traits Among LGB Individuals

2013 ◽  
Author(s):  
Jennifer C. Johnson ◽  
Caroline H. Stroud ◽  
Robert J. Cramer ◽  
James W. Crosby ◽  
Craig E. Henderson ◽  
...  
Keyword(s):  
Personality Traits

Role of Social Symptomatology in Understanding Dark Triad Personality Traits

2011 ◽  
Author(s):  
Rebecca Stead ◽  
Cynthia Fekken ◽  
Alexandra Kay ◽  
Kate Mcdermott
Keyword(s):  
Personality Traits ◽  
Dark Triad

Gender and Organizational Conflict Management: The Mediating Role of Personality

2018 ◽  
Author(s):  
Maciej Kościelniak ◽  
Jarosław Piotrowski ◽  
Magdalena Żemojtel-Piotrowska
Keyword(s):  
Conflict Management ◽  
Personality Traits ◽  
Structural Equation ◽  
Online Survey ◽  
Conflict Behavior ◽  
Equation Modeling ◽  
Conflict Management Styles ◽  
Mediating Role ◽  
Big Five Model

Many authors examined the interplay between gender and conflict management preferences, but those findings were often mixed and inconsistent. In the current paper we tried to explain those inconsistencies by investigating the mediating role of personality for the relationship of gender and conflict management. Rahim's inventory was used for identifying five conflict management styles, and Big Five Model theory was a base for assessing participants' personality traits. Data were collected from a sample of 1,055 working Poles (52.7% women), in an online survey. Based on the structural equation modeling we detected multiple indirect mediating paths of gender on conflict management via personality traits, while no direct effect of gender was observed. Despite some limitations, the study sheds light on the actual role of gender in conflict behavior and the importance of personality traits in the conflict management, both from a theoretical and practical perspective.

Role of personal values and personality traits on intention to recommend a destination

2020 ◽  
Author(s):  
Arnold Japutra ◽  
Sandra Maria Correia Loureiro ◽  
Shasha Wang
Keyword(s):  
Theory Of Planned Behavior ◽  
Personality Traits ◽  
Planned Behavior ◽  
Personal Values ◽  
Favorable Attitude ◽  
Extended Model ◽  
Extended Theory ◽  
Prosocial Values ◽  
Managerial Implications

In this study, the researchers explore the antecedents of tourists’ intention to recommend a destination using an extended Theory of Planned Behavior (TPB). Two personal values (i.e., prosocial and maturity) and two personality traits (i.e., extraversion and agreeableness), which are rarely studied but important elements for marketers to better understand the market (e.g., segment the market), are examined. To test the extended model of TPB, a survey (n=312) was conducted with tourists in Portugal. The researchers find support for the hypothesis that tourists with higher prosocial values, maturity values, and extraversion personality traits are more likely to have a favorable attitude toward a destination and a tendency to recommend the destination. Theoretical and managerial implications are discussed.

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