scholarly journals Toxicity of Cadmium in Soil-Plant-Human Continuum and Its Bioremediation Techniques

2020 ◽  
Author(s):  
Asik Dutta ◽  
Abhik Patra ◽  
Hanuman Singh Jatav ◽  
Surendra Singh Jatav ◽  
Satish Kumar Singh ◽  
...  
Keyword(s):  
Drinking Water ◽  
Urban Areas ◽  
Cadmium Toxicity ◽  
Chemical Properties ◽  
Agricultural Practices ◽  
Body Parts ◽  
Cd Toxicity ◽  
Body Weights ◽  
Reproductive Body ◽  
Kidney Liver

Cadmium (Cd) toxicity is highly detrimental for the human and largely originated from faulty industrial and agricultural practices. Cadmium toxicity can be observed in minute concentration and highly mobile in the soil–plant system and availability in soil is mainly governed by various physio-chemical properties of the soil. Cereals and vegetables cultivated in peri-urban areas, former mining and industrial areas accumulate Cd in toxic limit as they receive Cd from multiple ways. In general, when the total cadmium (Cd) concentration in soil exceeds 8 mg kg−1, or the bioavailable Cd concentration becomes >0.001 mg kg−1, or the Cd concentration in plant tissue reaches 3–30 mg kg−1most plants exhibit visible Cd toxicity symptoms. The impacts of Cd toxicity are seed germination, growth, photosynthesis, stomata conductance, enzyme activities and alteration in mineral nutrition. The major source of Cd in human is food chain cycle and causes disorders like “itai-itai” disease, cancer, and nephrotoxicity. Cadmium harms kidney, liver, bone and reproductive body parts and may be fatal in serious condition. WHO recommended the tolerable monthly Cd intake are 25 μg kg−1 body weights and in drinking water Cd concentration should not exceed 3 μg L−1. It is hard to remove these potent and hazardous metals from the environment as they have long mean residence time but, can be converted into less toxic form through bioremediation. This chapter focuses on the effect of Cd toxicity in soil–plant-human continuum and its bioremediation techniques to mitigate the Cd- toxicity.

An expert system for real-time well field management

2012 ◽  
Vol 12 (5) ◽  
pp. 699-706 ◽  
Author(s):  
B. S. Marti ◽  
G. Bauser ◽  
F. Stauffer ◽  
U. Kuhlmann ◽  
H.-P. Kaiser ◽  
...  
Keyword(s):  
Drinking Water ◽  
Expert System ◽  
Knowledge Base ◽  
Real Time ◽  
Urban Areas ◽  
Industrial Sites ◽  
Water Wells ◽  
Well Field ◽  
Field Management ◽  
Historical Management

Well field management in urban areas faces challenges such as pollution from old waste deposits and former industrial sites, pollution from chemical accidents along transport lines or in industry, or diffuse pollution from leaking sewers. One possibility to protect the drinking water of a well field is the maintenance of a hydraulic barrier between the potentially polluted and the clean water. An example is the Hardhof well field in Zurich, Switzerland. This paper presents the methodology for a simple and fast expert system (ES), applies it to the Hardhof well field, and compares its performance to the historical management method of the Hardhof well field. Although the ES is quite simplistic it considerably improves the water quality in the drinking water wells. The ES knowledge base is crucial for successful management application. Therefore, a periodic update of the knowledge base is suggested for the real-time application of the ES.

scholarly journals Seasonal variation and spatial distribution of carbonaceous aerosols in Taiwan

2010 ◽  
Vol 10 (19) ◽  
pp. 9563-9578 ◽  
Author(s):  
C. C.-K. Chou ◽  
C. T. Lee ◽  
M. T. Cheng ◽  
C. S. Yuan ◽  
S. J. Chen ◽  
...  
Keyword(s):  
Spatial Distribution ◽  
Rural Areas ◽  
Urban Areas ◽  
Air Pollutants ◽  
Chemical Properties ◽  
Anthropogenic Sources ◽  
Carbonaceous Aerosols ◽  
Urban Rural ◽  
Southern Taiwan ◽  
Northern Taiwan

Abstract. To investigate the physico-chemical properties of aerosols in Taiwan, an observation network was initiated in 2003. In this work, the measurements of the mass concentration and carbonaceous composition of PM10 and PM2.5 are presented. Analysis on the data collected in the first 5-years, from 2003 to 2007, showed that there was a very strong contrast in the aerosol concentration and composition between the rural and the urban/suburban stations. The five-year means of EC at the respective stations ranged from 0.9±0.04 to 4.2±0.1 μgC m−3. In rural areas, EC accounted for 2–3% of PM10 and 3–5% of PM2.5 mass loadings, comparing to 4–6% of PM10 and 4–8% of PM2.5 in the urban areas. It was found that the spatial distribution of EC was consistent with CO and NOx across the network stations, suggesting that the levels of EC over Taiwan were dominated by local sources. The measured OC was split into POC and SOC counterparts following the EC tracer method. Five-year means of POC ranged from 1.8±0.1 to 9.7±0.2 μgC m−3 among the stations. It was estimated that the POM contributed 5–17% of PM10 and 7–18% of PM2.5 in Taiwan. On the other hand, the five-year means of SOC ranged from 1.5±0.1 to 3.8±.3 μgC m−3. The mass fractions of SOM were estimated to be 9–19% in PM10 and 14–22% in PM2.5. The results showed that the SOC did not exhibit significant urban-rural contrast as did the POC and EC. A significant cross-station correlation between SOC and total oxidant was observed, which means the spatial distribution of SOC in Taiwan was dominated by the oxidant mixing ratio. Besides, correlation was also found between SOC and particulate nitrate, implying that the precursors of SOA were mainly from local anthropogenic sources. In addition to the spatial distribution, the carbonaceous aerosols also exhibited distinct seasonality. In northern Taiwan, the concentrations of all the three carbonaceous components (EC, POC, and SOC) reached their respective minima in the fall season. POC and EC increased drastically in winter and peaked in spring, whereas the SOC was characterized by a bimodal pattern with the maximal concentration in winter and a second mode in summertime. In southern Taiwan, minimal levels of POC and EC occurred consistently in summer and the maxima were observed in winter, whereas the SOC peaked in summer and declined in wintertime. The discrepancies in the seasonality of carbonaceous aerosols between northern and southern Taiwan were most likely caused by the seasonal meteorological settings that dominated the dispersion of air pollutants. Moreover, it was inferred that the Asian pollution outbreaks could have shifted the seasonal maxima of air pollutants from winter to spring in the northern Taiwan, and that the increases in biogenic SOA precursors and the enhancement in SOA yield were responsible for the elevated SOC concentrations in summer.

scholarly journals The regulation of phosphate-activated glutaminase activity and glutamine metabolism in the streptozotocin-diabetic rat

1984 ◽  
Vol 224 (1) ◽  
pp. 207-214 ◽  
Author(s):  
M Watford ◽  
E M Smith ◽  
E J Erbelding
Keyword(s):  
Drinking Water ◽  
Small Intestine ◽  
Glutamine Metabolism ◽  
Diabetic Rat ◽  
Complete Suppression ◽  
Chemically Induced ◽  
Phosphate Activated Glutaminase ◽  
Kidney Liver ◽  
Nh4cl Solution ◽  
Glutaminase Activity

The activity of phosphate-activated glutaminase was increased in the kidney, liver and small intestine of rats made diabetic for 6 days with injection of streptozotocin (75 mg/kg body wt.). Insulin prevented this increase in all three tissues. Treatment with NaHCO3, to correct the acidosis that accompanies diabetes, prevented the increase in renal glutaminase activity, but not that in liver or small intestine. Chemically induced acidosis (NH4Cl solution as drinking water) or alkalosis (NaHCO3 solution as drinking water) increased and decreased, respectively, glutaminase activity in the kidney, but were without significant effect on the activity in liver and small intestine. The increase in glutaminase activity in the small intestine during diabetes was due to an overall increase in the size of this organ, and was only detectable when activity was expressed in terms of whole organ, not mucosal scrapings or isolated enterocytes. Prolonged diabetes (40 days) resulted in an even greater increase in the size and glutaminase activity of the small intestine. Despite this marked increase in capacity for glutamine catabolism, arteriovenous-difference measurements showed a complete suppression of plasma glutamine utilization by the small intestine during diabetes, confirming the report by Brosnan, Man, Hall, Colbourne & Brosnan [(1983) Am. J. Physiol. 235, E261-E265].

Oral (Drinking Water) Two-Generation Reproductive Toxicity Study of Bromodichloromethane (BDCM) in Rats

2002 ◽  
Vol 21 (2) ◽  
pp. 115-146 ◽  
Author(s):  
M. S. Christian ◽  
R. G. York ◽  
A. M. Hoberman ◽  
L. C. Fisher ◽  
W. Ray Brown
Keyword(s):  
Drinking Water ◽  
Reproductive Toxicity ◽  
Clinical Signs ◽  
Sperm Parameters ◽  
Feed Consumption ◽  
Exposure Level ◽  
Organ Weights ◽  
Reduced Body ◽  
Body Weights ◽  
Adult Exposure

Bromodichloromethane (BDCM) was tested for reproductive toxicity in a two-generation study in CRL SD rats. Thirty rats/sex/group/generation were continuously provided BDCM in drinking water at 0 (control carrier, reverse osmosis membrane-processed water), 50, 150, and 450 ppm (0,4.1 to 12.6, 11.6 to 40.2, and 29.5 to 109.0 mg/kg/day, respectively). Adult human intake approximates 0.8 μg/kg/day (0.0008 mg/kg/day). P and F1 rats were observed for general toxicity (viability, clinical signs, water and feed consumption, body weights, organ weights [also three weanling F1 and F2 pups/sex/litter], histopathology [10/sex, 0-and 450-ppm exposure groups]) and reproduction (mating, fertility, abortions, premature deliveries, durations of gestation, litter sizes, sex ratios, viabilities, maternal behaviors, reproductive organ weights [also three weanling F1 and F2 pups/sex/litter], sperm parameters, and implantations. F1 rats were evaluated for age at vaginal patency or preputial separation. Ten P and F1 rats/sex from the 0-and 450-ppm exposure groups and rats at 50 and 150 ppm with reduced fertility were evaluated for histopathology (gross lesions, testes, intact epididymis, all F1 dams for number of primordial follicles). Developmental parameters in offspring included implantation and pup numbers, sexes, viabilities, body weights, gross external alterations, and reproductive parameters (F1 adults). Toxicologically important, statistically significant effects at 150 and/or 450 ppm included mortality and clinical signs associated with reduced absolute and relative water consumption, reduced body weights and weight gains, and reduced absolute and relative feed consumption (P and F1 rats). Significantly reduced body weights at 150 and 450 ppm were associated with reduced organ weights and increased organ weight ratios (% body and/or brain weight). Histopathology did not identify abnormalities. Small delays in sexual maturation (preputial separation, vaginal patency) and more F1 rats with prolonged diestrus were also attributable to severely reduced pup body weights. Mating, fertility, sperm parameters, and primordial ovarian follicular counts were unaffected. The no-observable-adverse-effect level (NOAEL) and the reproductive and developmental NOAELs for BDCM were at least 50 ppm (4.1 to 12.6 mg/kg/day), 5125 to 15,750 times the human adult exposure level, if delayed sexual maturational associated with severely reduced body weights is considered reproductive toxicity. If considered general toxicity, reproductive and developmental NOAELs for BDCM are greater than 450 ppm (29.5 to 109.0 mg/kg/day), or 36,875 to 136,250 times the human adult exposure level. Regardless, these data indicate that BDCM should not be identified as a risk to human reproductive performance or development of human conceptuses.

scholarly journals Immunotoxicity of Per- and Polyfluoroalkyl Substances: Insights into Short-Chain PFAS Exposure

Toxics ◽  
2021 ◽  
Vol 9 (5) ◽  
pp. 100
Author(s):  
Tracey Woodlief ◽  
Samuel Vance ◽  
Qing Hu ◽  
Jamie DeWitt
Keyword(s):  
Drinking Water ◽  
Nk Cell ◽  
Positive Control ◽  
Oral Exposure ◽  
Body Weights ◽  
Toxicological Data ◽  
Males And Females ◽  
Polyfluoroalkyl Substances ◽  
Compound Exposure ◽  
Control Terminal

Novel per- and polyfluoroalkyl substances (PFAS) were recently identified in drinking water sources throughout North Carolina. These include the perfluoroether acids (PFEAs) perfluoro-2-methoxyacetic acid (PFMOAA), perfluoro-2-methoxypropanoic acid (PFMOPrA), and perfluoro-4-methoxybutanioc acid (PFMOBA). Little toxicological data exist for these PFEAs. Therefore, the present study described signs of toxicity and immunotoxicity following oral exposure. Adult male and female C57BL/6 mice were exposed once/day for 30 days to PFMOAA (0, 0.00025, 0.025, or 2.5 mg/kg), PFMOPrA, or PFMOBA (0, 0.5, 5, or 50 mg/kg). A dose of 7.5 mg/kg of perfluorooctanoic acid (PFOA) was used as a positive control. Terminal body weights, and absolute liver, spleen, or thymus weights did not differ by dose for any compound; exposure to 50 mg/kg of PFMOBA increased relative liver weights in males. Changes in splenic cellularity were observed in males exposed to PFMOPrA and decreased numbers of B and natural killer (NK) cells were observed in males and females exposed to PFMOBA. Exposure did not alter NK cell cytotoxicity or T cell-dependent antibody responses at doses administered. Our results indicate that these “understudied” PFAS have toxicological potential but require additional investigation across endpoints and species, including humans, to understand health effects via drinking water exposure.

Measurement and Analysis of Multidimensional Poverty Using Fuzzy Set Approach

2021 ◽  
pp. 495-509
Keyword(s):  
Drinking Water ◽  
Fuzzy Set ◽  
Urban Areas ◽  
Multidimensional Poverty ◽  
Housing Conditions ◽  
Multidimensional Poverty Index ◽  
Rural And Urban ◽  
Measurement And Analysis ◽  
Individual Household ◽  
The Government

The study was carried out to measure and analyse aspect based multidimensional poverty in rural and urban Haryana using a fuzzy set approach. The necessary data for the study was obtained from the 69th round conducted in 2012 by the NSSO on drinking water, sanitation, hygiene, and housing conditions. The Totally Fuzzy and Relative Approach was used. The fuzzy multidimensional poverty index for rural, urban and overall Haryana was calculated based on drinking water, sanitation, and housing conditions. The results revealed that 33.28 percent of households in Haryana overall were multidimentionally poor, with 36.64 percent of households in rural and 30.46 percent in urban areas. The government should lay the water connections and water pipes, construction of individual household latrines, sanitary complex for women, school, and sanitation housing schemes for all BPL families under schemes initiated by the government to overcome poverty based on these aspects.

Characterization of NOM in a drinking water treatment process train with no disinfectant residual

2009 ◽  
Vol 9 (4) ◽  
pp. 379-386 ◽  
Author(s):  
S. A. Baghoth ◽  
M. Dignum ◽  
A. Grefte ◽  
J. Kroesbergen ◽  
G. L. Amy
Keyword(s):  
Drinking Water ◽  
Water Treatment ◽  
Organic Carbon ◽  
Distribution System ◽  
Chemical Properties ◽  
Drinking Water Treatment ◽  
Building Blocks ◽  
Fluorescence Excitation ◽  
Water Treatment Process ◽  
Water Treatment Plants

For drinking water treatment plants that do not use disinfectant residual in the distribution system, it is important to limit availability of easily biodegradable natural organic matter (NOM) fractions which could enhance bacterial regrowth in the distribution system. This can be achieved by optimising the removal of those fractions of interest during treatment; however, this requires a better understanding of the physical and chemical properties of these NOM components. Fluorescence excitation-emission matrix (EEM) and liquid chromatography with online organic carbon detection (LC-OCD) were used to characterize NOM in water samples from one of the two water treatment plants serving Amsterdam, The Netherlands. No disinfectant residual is applied in the distribution system. Fluorescence EEM and LC-OCD were used to track NOM fractions. Whereas fluorescence EEM shows the reduction of humic-like as well as protein-like fluorescence signatures, LC-OCD was able to quantify the changes in dissolved organic carbon (DOC) concentrations of five NOM fractions: humic substances, building blocks (hydrolysates of humics), biopolymers, low molecular weight acids and neutrals.

scholarly journals The mutagenic and some physico-chemical properties of organic residues obtained from drinking water by Amberlite XAD-2 and activated carbon extraction.

Eisei kagaku ◽  
1988 ◽  
Vol 34 (5) ◽  
pp. 389-400 ◽  
Author(s):  
SUKEO ONODERA ◽  
KEIICHIRO YOSHIMATSU ◽  
SEIGO NAKANO ◽  
HISAYO SAITOH ◽  
SHIZUO SUZUKI
Keyword(s):  
Drinking Water ◽  
Activated Carbon ◽  
Chemical Properties ◽  
Organic Residues ◽  
Physico Chemical

Immunotoxicity of an Electrochemically Fluorinated Aqueous Film-Forming Foam

2020 ◽  
Vol 178 (1) ◽  
pp. 104-114 ◽  
Author(s):  
Carrie A McDonough ◽  
Chastity Ward ◽  
Qing Hu ◽  
Samuel Vance ◽  
Christopher P Higgins ◽  
...  
Keyword(s):  
Drinking Water ◽  
Body Weight ◽  
Perfluorooctane Sulfonate ◽  
Positive Control ◽  
Film Forming ◽  
Body Weights ◽  
Specific Antibody Production ◽  
Fire Suppressants ◽  
Contaminated Drinking Water ◽  
Induced Changes

Abstract Aqueous film-forming foams (AFFFs) are complex per- and polyfluoroalkyl substance (PFAS)-containing mixtures used extensively as fire suppressants. AFFF-impacted groundwater and surface water have contaminated drinking water with PFASs in many communities, raising concerns about health effects from drinking water exposures. As individual PFASs have been identified as immune hazards, the immunotoxicity of complex PFAS mixtures is also a concern. Adult female and male C57BL/6 mice were given a commercial AFFF formulation for 10 days via gavage; administered dose was based on combined content of perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS) measured in the formulation (0, 1.88, 3.75, 7.5, or 10 mg PFOS+PFOA/kg body weight). A PFOA positive control of 7.5 mg/kg body weight was also given. Compared with the 0 mg/kg group, the following changes were noted: Body weights of males exposed to 7.5 and 10 mg PFOS+PFOA/kg were reduced by 15%, on average; female body weights did not differ. Average relative liver weights were increased 50%–200% in males and 37.5%–193% in females and liver peroxisome proliferation was increased 2- to 12-fold in all doses of both sexes. Antigen-specific antibody production was suppressed, on average, by 13% in males and by 12.4% in females across all doses. Spleen cellularity and lymphocyte subpopulations did not differ by dose for either sex. Our data indicate that though this complex PFAS mixture contained fairly low PFOA content, it induced changes in C57BL/6 mice similar to changes induced by PFOA alone, likely due to the presence of PFOS and many other PFASs.

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