scholarly journals Acrylic-Based Hydrogels as Advanced Biomaterials

2020 ◽  
Author(s):  
Ángel Serrano-Aroca ◽  
Sanjukta Deb
Keyword(s):  
Advanced Biomaterials

A multifunctional substance P-conjugated chitosan hydrochloride hydrogel accelerates full-thickness wound healing by enhancing synchronized vascularization, extracellular matrix deposition, and nerve regeneration

2021 ◽  
Author(s):  
Hao Li ◽  
Mengna Li ◽  
Pei Liu ◽  
Kai-Yang Wang ◽  
Haoyu Fang ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Wound Healing ◽  
Full Thickness ◽  
Matrix Deposition ◽  
Chitosan Hydrochloride ◽  
Reconstructive Microsurgery ◽  
Extracellular Matrix Deposition ◽  
Advanced Biomaterials ◽  
Native Skin ◽  
Full Thickness Wound

Due to the native skin limitations and the complexity of reconstructive microsurgery, advanced biomaterials are urgently required to promote wound healing for severe skin defects caused by accidents and disasters....

Advanced biomaterials for sustainable applications in the food industry: Updates and challenges

2021 ◽  
pp. 117071
Author(s):  
Reshmy R ◽  
Eapen Philip ◽  
Aravind Madhavan ◽  
Raveendran Sindhu ◽  
Arivalagan Pugazhendhi ◽  
...  
Keyword(s):  
Food Industry ◽  
Advanced Biomaterials

scholarly journals Electrophoretic deposition of biomaterials

2010 ◽  
Vol 7 (suppl_5) ◽  
Author(s):  
A. R. Boccaccini ◽  
S. Keim ◽  
R. Ma ◽  
Y. Li ◽  
I. Zhitomirsky
Keyword(s):  
Electrophoretic Deposition ◽  
Functional Coatings ◽  
Tissue Engineering Scaffolds ◽  
Bioactive Coatings ◽  
Inorganic Coatings ◽  
Wide Range ◽  
Particulate Form ◽  
Advanced Biomaterials ◽  
Biological Entities ◽  
And Control

Electrophoretic deposition (EPD) is attracting increasing attention as an effective technique for the processing of biomaterials, specifically bioactive coatings and biomedical nanostructures. The well-known advantages of EPD for the production of a wide range of microstructures and nanostructures as well as unique and complex material combinations are being exploited, starting from well-dispersed suspensions of biomaterials in particulate form (microsized and nanoscale particles, nanotubes, nanoplatelets). EPD of biological entities such as enzymes, bacteria and cells is also being investigated. The review presents a comprehensive summary and discussion of relevant recent work on EPD describing the specific application of the technique in the processing of several biomaterials, focusing on (i) conventional bioactive (inorganic) coatings, e.g. hydroxyapatite or bioactive glass coatings on orthopaedic implants, and (ii) biomedical nanostructures, including biopolymer–ceramic nanocomposites, carbon nanotube coatings, tissue engineering scaffolds, deposition of proteins and other biological entities for sensors and advanced functional coatings. It is the intention to inform the reader on how EPD has become an important tool in advanced biomaterials processing, as a convenient alternative to conventional methods, and to present the potential of the technique to manipulate and control the deposition of a range of nanomaterials of interest in the biomedical and biotechnology fields.

scholarly journals Biomaterials and oxygen join forces to shape the immune response and boost SARS-CoV-2 vaccines

2020 ◽  
Author(s):  
Thibault Colombani ◽  
Loek Eggermont ◽  
Zachary Rogers ◽  
Lindsay McKay ◽  
Laura Avena ◽  
...  
Keyword(s):  
Immune Response ◽  
Neutralizing Antibodies ◽  
High Titer ◽  
Full Potential ◽  
Protein Subunit ◽  
Subunit Vaccines ◽  
Health Crisis ◽  
Th2 Immune Response ◽  
Protective Antibodies ◽  
Advanced Biomaterials

Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to an unprecedented global health crisis, resulting in a critical need for effective vaccines that generate protective antibodies. Protein subunit vaccines represent a promising approach but often lack the immunogenicity required for strong immune stimulation. To overcome this challenge, we first demonstrate that advanced biomaterials boost effectiveness of SARS-CoV-2 protein subunit vaccines. Additionally, we report that oxygen is a powerful immunological co-adjuvant, a game-changer in the field for unlocking the full potential of vaccines. Mice immunized with oxygen-generating cryogel vaccines exhibited a robust and balanced Th1 and Th2 immune response, leading to sustained and high titer production of neutralizing antibodies against SARS-CoV-2. Our data indicate that this platform is a revolutionary technology with the potential to reinforce any vaccine.

An injectable gellan gum-based hydrogel that inhibits Staphylococcus aureus for infected bone defect repair

2021 ◽  
Author(s):  
Laijun Xu ◽  
Qing Ye ◽  
Jiaojiao Yang ◽  
xie jing ◽  
wentao jiang ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Bone Defect ◽  
Bone Defects ◽  
Gellan Gum ◽  
Anatomical Structures ◽  
Bone Defect Repair ◽  
Clinical Challenge ◽  
Defect Repair ◽  
Advanced Biomaterials

The treatment of infected bone defects in complex anatomical structures, such as oral and maxillofacial structures, remains an intractable clinical challenge. Therefore, advanced biomaterials that have excellent anti-infection activity and...

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