scholarly journals Somatic Nerve Reconstruction and Reinnervation

2020 ◽  
Author(s):  
Lin Yang ◽  
Ping Wang
Keyword(s):  
Nerve Reconstruction ◽  
Somatic Nerve

Modular Bioactive Scaffold for Facial Nerve Reconstruction

2015 ◽  
Vol 76 (S 01) ◽  
Author(s):  
M. Röthlisberger ◽  
S. Madduri ◽  
S. Marbacher ◽  
D. Schaefer ◽  
D. Kalbermatten ◽  
...  
Keyword(s):  
Facial Nerve ◽  
Nerve Reconstruction ◽  
Facial Nerve Reconstruction

Nerve Graft Length and Recovery of Elbow Flexion Muscle Strength in Patients With Traumatic Brachial Plexus Injuries: Case Series

2021 ◽  
Author(s):  
Mariano Socolovsky ◽  
Gilda di Masi ◽  
Gonzalo Bonilla ◽  
Ana Lovaglio ◽  
Kartik G Krishnan
Keyword(s):  
Brachial Plexus ◽  
Case Series ◽  
Target Function ◽  
Elbow Flexion ◽  
Nerve Graft ◽  
Spinal Accessory Nerve ◽  
Accessory Nerve ◽  
Nerve Reconstruction ◽  
Muscle Recovery ◽  
Spinal Accessory

Abstract BACKGROUND Traumatic brachial plexus injuries cause long-term maiming of patients. The major target function to restore in complex brachial plexus injury is elbow flexion. OBJECTIVE To retrospectively analyze the correlation between the length of the nerve graft and the strength of target muscle recovery in extraplexual and intraplexual nerve transfers. METHODS A total of 51 patients with complete or near-complete brachial plexus injuries were treated with a combination of nerve reconstruction strategies. The phrenic nerve (PN) was used as axon donor in 40 patients and the spinal accessory nerve was used in 11 patients. The recipient nerves were the anterior division of the upper trunk (AD), the musculocutaneous nerve (MC), or the biceps branches of the MC (BBs). An index comparing the strength of elbow flexion between the affected and the healthy arms was correlated with the choice of target nerve recipient and the length of nerve grafts, among other parameters. The mean follow-up was 4 yr. RESULTS Neither the choice of MC or BB as a recipient nor the length of the nerve graft showed a strong correlation with the strength of elbow flexion. The choice of very proximal recipient nerve (AD) led to axonal misrouting in 25% of the patients in whom no graft was employed. CONCLUSION The length of the nerve graft is not a negative factor for obtaining good muscle recovery for elbow flexion when using PN or spinal accessory nerve as axon donors in traumatic brachial plexus injuries.

scholarly journals Facial Nerve Reconstruction with Free Vascularized Composite Nerve Flap from Intrapetrous Portion to Terminal Branches—Case Report

2021 ◽  
Author(s):  
Pedro C. Cavadas ◽  
Magdalena Baklinska
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Facial Nerve ◽  
Free Flap ◽  
Nerve Reconstruction ◽  
Nerve Stump ◽  
Stylomastoid Foramen ◽  
Facial Nerve Reconstruction ◽  
Delayed Reconstruction

AbstractThe case presented here is a delayed reconstruction of a facial nerve defect after radical parotidectomy without a useful nerve stump at the stylomastoid foramen. A composite free flap was used to reconnect the nerve’s intrapetrous portion to the peripheral branches and reconstruct the soft-tissue deficit.

scholarly journals “ALL IN ONE OR (W)HOLE IN ONE REPAIR” for Adult Total Brachial Plexus Palsy

2021 ◽  
Author(s):  
V. Purushothaman ◽  
K. Vinoth Kumar ◽  
Sabari Girish Ambat ◽  
R. Venkataswami
Keyword(s):  
Brachial Plexus ◽  
Hand Function ◽  
The Body ◽  
Salvage Procedure ◽  
Brachial Plexus Palsy ◽  
Nerve Reconstruction ◽  
Muscle Transfer ◽  
Young Males ◽  
Elbow Function ◽  
Better Than

Abstract Background Total brachial plexus palsy (TBPP) accounts for nearly 50% of all brachial plexus injuries. Since achieving a good functional hand was almost impossible, the aim was settled to get a good shoulder and elbow function. It was Gu, who popularized the concept of utilizing contralateral C7 (CC7) with vascularized ulnar nerve graft (VUNG) to get some hand function. We have modified it to suit our patients by conducting it as a single-stage procedure, thereby trying to get a functional upper limb. Methods From 2009 to 2014, we had 20 TBPP patients. We feel nerve reconstruction is always better than any other salvage procedure, including free muscle transfer. We modified Gu's concept and present our concept of total nerve reconstruction as “ALL IN ONE OR (W)HOLE IN ONE REPAIR.” Results All patients able to move their reconstructed limbs independently or with the help of contralateral limbs. Three patients developed hook grip and one patient was able to incorporate limbs to do bimanual jobs. One important observation is that all the reconstructed limbs regain the bulk, and to a certain extent, the attitude and appearance looks normal, as patients no longer hide it or hang it in a sling. Conclusion Adult brachial plexus injury itself is a devastating injury affecting young males. By doing this procedure, the affected limb is not dissociated from the rest of the body and rehabilitation can be aimed to get a supportive limb.

Change of propagation speed of action potential in axons bunch of frog"s somatic nerve ex vivo and processes of inactivation under local laser influence

2005 ◽  
Author(s):  
Alexander G. Akchurin ◽  
Garif G. Akchurin ◽  
Roman P. Gorshkov ◽  
Leonid A. Melnikov ◽  
Vyacheslav G. Ninel ◽  
...  
Keyword(s):  
Action Potential ◽  
Ex Vivo ◽  
Propagation Speed ◽  
Somatic Nerve

scholarly journals Long-Term Effect of Endoscopic Sympathetic Nerve Reconstruction for Side Effects after Endoscopic Sympathectomy

2016 ◽  
Vol 65 (06) ◽  
pp. 484-490 ◽  
Author(s):  
Timo Telaranta ◽  
Tuomo Rantanen
Keyword(s):  
Side Effects ◽  
Sympathetic Nerve ◽  
Nerve Reconstruction ◽  
Endoscopic Thoracic Sympathectomy ◽  
Thoracic Sympathectomy ◽  
Long Term Effect ◽  
Primary Hyperhidrosis ◽  
The Mean

Background Endoscopic thoracic sympathectomy (ETS) is an effective treatment for primary hyperhidrosis. However, compensatory sweating (CS) may occur in many patients. Sympathetic nerve reconstruction (SNR) can be used to counteract severe CS, but the studies on the effects of SNR are few. Patients and Methods Nineteen out of 150 SNR patients were contacted by employing a long-term questionnaire. In this questionnaire, different kinds of sweating were evaluated using a four-graded symptom analysis and the visual analog scale before ETS, after ETS, and after SNR. Results The mean age of the 16 male and 3 female patients at the SNR was 32 years. The mean follow-up was 87 months. According to the long-term questionnaire, the benefit was either excellent (4 patients, 21%), good (3 patients, 15.8%), or reasonable (7 patients, 36.8%) in 14 patients (73.8%), while the benefit was questionable in 1 patient (5.3%). For three patients (15.8%), no benefit was found, and in one patient (5.3%), the situation had deteriorated. Conclusions Improvement in the side effects of ETS after SNR was found in nearly 75% of the patients. This indicates that SNR can be considered as an alternative treatment for patients with severe CS after ETS that is unresponsive to conservative treatment.

Neurilemoma of the Median Nerve - Surgical Strategies Based on a Case Report

2014 ◽  
Vol 86 (9) ◽  
Author(s):  
Łukasz Ulatowski ◽  
Anna Kaniewska
Keyword(s):  
Case Report ◽  
Median Nerve ◽  
Nerve Trunk ◽  
Reconstruction Technique ◽  
Nerve Reconstruction ◽  
Surgical Strategies ◽  
Second Procedure ◽  
Relationship Of ◽  
The Relationship ◽  
Neural Sheath

AbstractThe study presented a case of a patient with a neurilemoma of the median nerve. It presented as a six centemeters tumor, at the level of the proximal one third of the arm with only mild paraesthesias within frst to third ray of the hand. MRI showed the relationship of the tumor and the median nerve, and allowed for the preliminary diagnose of a benign peripheral neural sheath tumor (neurilemoma or neurofibroma). During the first operation the tumor has not been excised, because nerve reconstruction technique was not available. During the second procedure excision of the tumor has been performed without resection of the median nerve trunk with no postoperative deficiencies. The paper provides a detailed description of a surgical procedure. The presented case, like current publications shows that peripheral neural sheath tumor may be usually excised without resection of the nerve trunk, although the possibility of nerve fascicles injury or the need to excise them in the case of neurofibroma clearly suggest that these type of operations should be carried out in centers with microsurgical facilities.

Processed nerve allografts for peripheral nerve reconstruction: A multicenter study of utilization and outcomes in sensory, mixed, and motor nerve reconstructions

Microsurgery ◽  
2011 ◽  
Vol 32 (1) ◽  
pp. 1-14 ◽  
Author(s):  
Darrell N. Brooks ◽  
Renata V. Weber ◽  
Jerome D. Chao ◽  
Brian D. Rinker ◽  
Jozef Zoldos ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Multicenter Study ◽  
Motor Nerve ◽  
Nerve Reconstruction

Matrix Metalloproteinase-9 is Involved in the Fibrotic Process in Denervated Muscles after Sciatic Nerve Trauma and Recovery

2021 ◽  
Author(s):  
Oleksii Goncharuk ◽  
Serhii Savosko ◽  
Artem Tykhomyrov ◽  
Mykhailo Guzyk ◽  
Volodymyr Medvediev ◽  
...  
Keyword(s):  
Polyethylene Glycol ◽  
Matrix Metalloproteinase ◽  
Skeletal Muscles ◽  
Gelatin Zymography ◽  
Matrix Metalloproteinase 9 ◽  
Nerve Reconstruction ◽  
Fibrotic Process ◽  
Collagen Density ◽  
Denervated Muscles ◽  
Metalloproteinase 9

AbstractFibrosis of the injured muscles is a problem of recovery from trauma and denervation. The aim of the work was to investigate the interconnection of matrix metalloproteinase-9 (ММР-9) activity in denervated muscles with fibrosis and to estimate its role in nerve restoration by the epineurial suture, fibrin-based glue, and polyethylene glycol hydrogel. The activity of matrix metalloproteinases was estimated by gelatin zymography. Collagen density in muscles was determined histochemically. An increased level of the active MMP-9 is associated with the fibrous changes in the denervated skeletal muscles and after an epineurial suture. The use of fibrin glue and polyethylene glycol hydrogel resulted in a lower level of collagen and ММР-9 activity, which may be a therapeutic target in the treatment of neuromuscular lesions, and has value in fibrosis analysis following microsurgical intervention for peripheral nerve reconstruction.

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