scholarly journals A Balanced Slew-Rate High-Voltage Integrated Bipolar Pulse Generator for Medical Ultrasonic Imaging Applications

2020 ◽  
Author(s):  
Chin Hsia
Keyword(s):  
High Voltage ◽  
Pulse Generator ◽  
Ultrasonic Imaging ◽  
Slew Rate ◽  
Bipolar Pulse

A compact subnanosecond high-voltage bipolar pulse generator with spark gaps

2010 ◽  
Vol 53 (6) ◽  
pp. 825-829 ◽  
Author(s):  
M. R. Ul’maskulov ◽  
S. A. Shunailov ◽  
K. A. Sharypov ◽  
V. G. Shpak ◽  
M. I. Yalandin
Keyword(s):  
High Voltage ◽  
Pulse Generator ◽  
Bipolar Pulse

scholarly journals High-Frequency and High-Voltage Asymmetric Bipolar Pulse Generator for Electroporation Based Technologies and Therapies

Electronics ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 1203
Author(s):  
Eva Pirc ◽  
Damijan Miklavčič ◽  
Katja Uršič ◽  
Gregor Serša ◽  
Matej Reberšek
Keyword(s):  
High Voltage ◽  
Repetition Rate ◽  
High Frequency ◽  
Pulse Generator ◽  
Biological Effects ◽  
Economic Evaluations ◽  
Bipolar Pulse ◽  
Electric Pulses ◽  
Custom Made

Currently, in high-frequency electroporation, much progress has been made but limited to research groups with custom-made laboratory prototype electroporators. According to the review of electroporators and economic evaluations, there is still an area of pulse parameters that needs to be investigated. The development of an asymmetric bipolar pulse generator with a maximum voltage of 4 kV and minimum duration time of a few hundred nanoseconds, would enable in vivo evaluation of biological effects of high-frequency electroporation pulses. Herein, from a series of most commonly used drivers and optical isolations in high-voltage pulse generators the one with optimal characteristics was used. In addition, the circuit topology of the developed device is described in detail. The developed device is able to generate 4 kV pulses, with theoretical 131 A maximal current and 200 ns minimal pulse duration, the maximal pulse repetition rate is 2 MHz and the burst maximal repetition rate is 1 MHz. The device was tested in vivo. The effectiveness of electrochemotherapy of high-frequency electroporation pulses is compared to “classical” electrochemotherapy pulses. In vivo electrochemotherapy with high-frequency electroporation pulses was at least as effective as with “classical” well-established electric pulses, resulting in 86% and 50% complete responses, respectively. In contrast to previous reports, however, muscle contractions were comparable between the two protocols.

A Modular Step-Up High-Voltage Bipolar Pulse Generator

2019 ◽  
Vol 47 (5) ◽  
pp. 2736-2741 ◽  
Author(s):  
Hossein Gholamalitabar ◽  
Jafar Adabi ◽  
Mohammad Rezanejad
Keyword(s):  
High Voltage ◽  
Pulse Generator ◽  
Bipolar Pulse

High voltage nanosecond pulse generator based on avalanche transistor Marx bank circuit and linear transformer driver

2021 ◽  
Vol 92 (3) ◽  
pp. 034715
Author(s):  
Zichen Deng ◽  
Qi Yuan ◽  
Saikang Shen ◽  
Jiaqi Yan ◽  
Yanan Wang ◽  
...  
Keyword(s):  
High Voltage ◽  
Pulse Generator ◽  
Nanosecond Pulse ◽  
Linear Transformer Driver
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