scholarly journals Defence against Oxidative Stress and Insecticides in Musca domestica

2020 ◽  
Author(s):  
Tan Yong Hao ◽  
Siti Nasuha Hamzah ◽  
Zazali Alias
Keyword(s):  
Oxidative Stress ◽  
Musca Domestica

Anti-atherosclerotic effect of housefly (Musca domestica) maggot-derived protein-enriched extracts by dampened oxidative stress in apolipoprotein E-deficient mice

RSC Advances ◽  
2016 ◽  
Vol 6 (107) ◽  
pp. 105363-105370 ◽  
Author(s):  
Xiao Mingzhu ◽  
Jin Xiaobao ◽  
Tang Futian ◽  
Wang Lijing ◽  
Mao Jianwen ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Apolipoprotein E ◽  
Musca Domestica ◽  
Developed Countries ◽  
Morbidity And Mortality ◽  
Deficient Mice

Despitemany therapeutic advances, atherosclerosis remains the leading cause of morbidity and mortality in developed countries.

Housefly (Musca domestica) larvae powder, preventing oxidative stress injury via regulation of UCP4 and CyclinD1 and modulation of JNK and P38 signaling in APP/PS1 mice

2019 ◽  
Vol 10 (1) ◽  
pp. 235-243 ◽  
Author(s):  
Yinru He ◽  
Xia Yang ◽  
Mengya Jiao ◽  
Shailendra Anoopkumar-Dukie ◽  
Yu Zeng ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Musca Domestica ◽  
Stress Injury ◽  
Oxidative Stress Injury

Housefly (Musca domestica) Larvae powder (HL) is rich in antioxidants.

Polydatin attenuates cadmium-induced oxidative stress via stimulating SOD activity and regulating mitochondrial function in Musca domestica larvae

Chemosphere ◽  
2020 ◽  
Vol 248 ◽  
pp. 126009 ◽  
Author(s):  
Yuming Zhang ◽  
Yajing Li ◽  
Qin Feng ◽  
Menghua Shao ◽  
Fengyu Yuan ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Musca Domestica ◽  
Mitochondrial Function ◽  
Sod Activity

scholarly journals Bimodal Behavior of Ascorbic Acid in Musca domestica Larvae

2021 ◽  
Vol 12 (4) ◽  
pp. 5199-5216
Keyword(s):  
Oxidative Stress ◽  
Ascorbic Acid ◽  
Musca Domestica ◽  
Food Supplement ◽  
Water Soluble ◽  
Dependent Manner ◽  
Concentration Dependent Manner ◽  
Dietary Antioxidant ◽  
High Concentrations ◽  
Normal Food

Ascorbic acid (Vitamin C) is an excellent water-soluble dietary antioxidant, well known to protect the biomolecules from oxidative stress-linked damages. It is reported to show a contrary behavior by inflicting pro-oxidant effects under varied, altered circumstances. The present work is an attempt to study the antioxidant and pro-oxidant behavior of ascorbic acid in Musca domestica larvae. Its pro-oxidant properties were tested by exposing the larvae to various concentrations of ascorbic acid. For confirming its oxidant scavenging properties, its effects on the antioxidant enzyme profiles were studied in both the normal and stress-induced M. domestica larvae. Oxidative stress was induced by adding D-Galactose (D-Gal) to the normal food supplement of the larvae. Outcomes of the study demonstrate that ascorbic acid acts as an efficient antioxidant when added in lower concentrations, but at high concentrations, it induces oxidative stress in the larvae, thus acting as a pro-oxidant. At the concentration of 10 mM, ascorbic acid significantly reduced the oxidative stress induced by D-Gal (p < 0.05) and maintained the percent pupal survival and percent eclosion. In conclusion, we suggest that ascorbic acid may function as an antioxidant and pro-oxidant in a concentration-dependent manner under normal physiological conditions.

scholarly journals Enhanced Antioxidant and Cytotoxic Potentials of Lipopolysaccharides-Injected Musca domestica Larvae

Pharmaceutics ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 1111
Author(s):  
Islam El-Garawani ◽  
Hesham El-Seedi ◽  
Shaden Khalifa ◽  
Islam H. El Azab ◽  
Marwa Abouhendia ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Superoxide Dismutase ◽  
Musca Domestica ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Vero Cells ◽  
Control Group ◽  
Larval Hemolymph ◽  
Mcf 7

The usage of insects as a sustainable and functional natural products resource is a new promise in complementary and alternative medicine. The present study aimed to investigate the ability of Musca domestica (housefly) larval hemolymph (insect blood) to display the enhanced in vitro antioxidant and cytotoxic effects. The oxidative stress (OS) was elicited by inducing lipopolysaccharides (LPS) treatment as an exogenous stressor. Determination of superoxide dismutase 1 (SOD1), glutathione (GSH), malondialdehyde (MDA) and total antioxidant capacity (TAC), and mRNA and protein expressions of SOD1, was investigated as confirmatory markers of oxidative stress induction. Cytotoxicity on cancerous MCF-7 and normal Vero cells were also evaluated using an MTT assay at 24 h post-injection. The injection of LPS induced a significant (p < 0.05) increase in SOD, GSH and TAC, whereas, the MDA was diminished. Hemolymph was collected from normal and treated larvae after 6, 12 and 24 h. The M. domestica superoxide dismutase (MdSOD1) transcripts were significantly (p < 0.05) upregulated 6 and 12 h post-treatment, while a significant downregulation was observed after 24 h. Western blot analysis showed that MdSOD1 was expressed in the hemolymph of the treated larvae with an increase of 1.2 folds at 6 and 12 h and 1.6 folds at 24 h relative to the control group. LPS-treated larval hemolymphs exhibited significant cytotoxicity with respect to the untreated ones against MCF-7 while Vero cells showed no cytotoxicity for both hemolymphs. The DPPH free radical scavenging activity was examined and a significant antioxidant potential potency was observed at 6 h (50% maximal inhibitory concentration (IC50): 63.3 ± 3.51 µg/mL) when compared to the control M. domestica larval hemolymph (IC50: 611.7 ± 10.41 µg/mL). Taken together, M. domestica larval hemolymph exhibited enhanced antioxidant and consequently increased cytotoxic capacities under stressed conditions.

scholarly journals Correction: Housefly (Musca domestica) larvae powder, preventing oxidative stress injury via regulation of UCP4 and CyclinD1 and modulation of JNK and P38 signaling in APP/PS1 mice

2019 ◽  
Vol 10 (10) ◽  
pp. 6945-6945
Author(s):  
Yinru He ◽  
Xia Yang ◽  
Mengya Jiao ◽  
Shailendra Anoopkumar-Dukie ◽  
Yu Zeng ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Musca Domestica ◽  
Stress Injury ◽  
Oxidative Stress Injury

Correction for ‘Housefly (Musca domestica) larvae powder, preventing oxidative stress injury via regulation of UCP4 and CyclinD1 and modulation of JNK and P38 signaling in APP/PS1 mice’ by Yinru He et al., Food Funct., 2019, 10, 235–243.

Iron induces oxidative stress and may alter the rate of aging in the housefly, Musca domestica

1985 ◽  
Vol 32 (1) ◽  
pp. 33-38 ◽  
Author(s):  
R.S. Sohal ◽  
R.G. Allen ◽  
K.J. Farmer ◽  
R.K. Newton
Keyword(s):  
Oxidative Stress ◽  
Musca Domestica
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