scholarly journals Modulation of Edible Plants on Hepatocellular Carcinoma Induced by Aflatoxin B1

2020 ◽  
Author(s):  
Peeradon Tuntiteerawit ◽  
Tichakorn Singto ◽  
Anupon Tadee ◽  
Supatra Porasuphatana
Keyword(s):  
Hepatocellular Carcinoma ◽  
Aflatoxin B1 ◽  
Edible Plants

Aflatoxin B1 DNA adducts in smeared tumor tissue from patients with hepatocellular carcinoma

Hepatology ◽  
1992 ◽  
Vol 16 (5) ◽  
pp. 1150-1155 ◽  
Author(s):  
Chien-Jen Chen ◽  
Yu-Jing Zhang ◽  
Sheng-Nan Lu ◽  
Regina M. Santella
Keyword(s):  
Hepatocellular Carcinoma ◽  
Dna Adducts ◽  
Aflatoxin B1 ◽  
Tumor Tissue

scholarly journals Expression of P62 in hepatocellular carcinoma involving hepatitis B virus infection and aflatoxin B1 exposure

2017 ◽  
Vol 6 (10) ◽  
pp. 2357-2369 ◽  
Author(s):  
Xiao Xiang ◽  
Hong-Gui Qin ◽  
Xue-Mei You ◽  
Yan-Yan Wang ◽  
Lu-Nan Qi ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Hepatitis B Virus ◽  
Virus Infection ◽  
Hepatitis B ◽  
Aflatoxin B1 ◽  
Hepatitis B Virus Infection ◽  
B Virus

scholarly journals Deregulated expression of a novel gene, NC33, in aflatoxin B1-induced rat hepatocellular carcinoma K2 cells

2005 ◽  
Vol 55 (2) ◽  
pp. 111-115
Author(s):  
Nobuya KURABE ◽  
Yuko KOMIYA ◽  
Seiichi MOCHIZUKI ◽  
Kumiko KATAGIRI ◽  
Akinori SUGIYAMA ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Aflatoxin B1 ◽  
Novel Gene

scholarly journals MicroRNA-24 Modulates Aflatoxin B1-Related Hepatocellular Carcinoma Prognosis and Tumorigenesis

2014 ◽  
Vol 2014 ◽  
pp. 1-13 ◽  
Author(s):  
Yi-Xiao Liu ◽  
Xi-Dai Long ◽  
Zhi-Feng Xi ◽  
Yun Ma ◽  
Xiao-Ying Huang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Dna Adducts ◽  
Aflatoxin B1 ◽  
Tissue Samples ◽  
Noncancerous Tissue ◽  
Free Survival ◽  
Tumor Tissues ◽  
Neoplastic Process ◽  
First Time

MicroRNA-24 (miR-24) may be involved in neoplastic process; however, the role of this microRNA in the hepatocellular carcinoma (HCC) related to aflatoxin B1 (AFB1) has not been well elaborated. Here, we tested miR-24 expression in 207 pathology-diagnosed HCC cases from high AFB1 exposure areas and HCC cells. We found that miR-24 was upregulated in HCC tumor tissues relative to adjacent noncancerous tissue samples, and that the high expression of miR-24 was significantly correlated with larger tumor size, higher microvessel density, and tumor dedifferentiation. Additionally, this microRNA overexpression modified the recurrence-free survival (relative hazard ratio [HR], 4.75; 95% confidence interval [CI], 2.66–8.47) and overall survival (HR=3.58, 95% CI = 2.34–5.46) of HCC patients. Furthermore, we observed some evidence of joint effects between miR-24 and AFB1 exposure on HCC prognosis. Functionally, miR-24 overexpression progressed tumor cells proliferation, inhibited cell apoptosis, and developed the formation of AFB1-DNA adducts. These results indicate for the first time that miR-24 may modify AFB1-related HCC prognosis and tumorigenesis.

scholarly journals Aflatoxin B1 Exposure, Hepatitis B Virus Infection, and Hepatocellular Carcinoma in Taiwan

2009 ◽  
Vol 18 (3) ◽  
pp. 846-853 ◽  
Author(s):  
Hui-Chen Wu ◽  
Qiao Wang ◽  
Hwai-I Yang ◽  
Habibul Ahsan ◽  
Wei-Yann Tsai ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Hepatitis B Virus ◽  
Virus Infection ◽  
Hepatitis B ◽  
Aflatoxin B1 ◽  
Hepatitis B Virus Infection ◽  
B Virus

Aflatoxin B1 exposure and the risk of hepatocellular carcinoma in Iranian carriers of viral hepatitis B and C

Toxin Reviews ◽  
2018 ◽  
Vol 38 (3) ◽  
pp. 234-239 ◽  
Author(s):  
Nasim Habibi ◽  
Mohsen Nassiri-Toosi ◽  
Heidar Sharafi ◽  
Seyed Moayed Alavian ◽  
Masoomeh Shams-Ghahfarokhi ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Hepatitis B ◽  
Viral Hepatitis ◽  
Aflatoxin B1 ◽  
Viral Hepatitis B
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