scholarly journals Introductory Chapter: Changes in the Approach of the Patient with Endometriosis and the Development of Genetics and Molecular Biology in Gynecology

2019 ◽  
Author(s):  
Giovana Aparecida Gonçalves
Keyword(s):  
Molecular Biology

The senses

2019 ◽  
pp. 1-17
Author(s):  
Gordon L. Fain
Keyword(s):  
Molecular Biology ◽  
Patch Clamp ◽  
Gene Cloning ◽  
Extracellular Recording ◽  
Sensory Transduction ◽  
Cloning And Expression ◽  
Gene Cloning And Expression ◽  
Patch Clamp Recording ◽  
The Senses

“The senses” is the introductory chapter of the book Sensory Transduction and describes early studies in the anatomy of sense organs and physiology of the senses. It introduces methods in physiology and molecular biology, which were critical tools used to unlock the secrets of sensation, including intracellular and extracellular recording, patch-clamp recording, gene cloning and expression, and structural studies such as cryo-EM. It concludes by describing in detail the discovery of the piezo proteins, which are the stretch-sensitive channels now known to be responsible for much of mammalian touch and proprioception.

Electron Microscopy in Molecular Biology

1967 ◽  
Vol 25 ◽  
pp. 2-3
Author(s):  
Cecil E. Hall
Keyword(s):  
Electron Microscopy ◽  
Molecular Biology ◽  
Noise Level ◽  
Molecular Structures ◽  
Material Structure ◽  
The Arts ◽  
Shadow Casting ◽  
Electron Image ◽  
High Degree ◽  
Very High

The visualization of organic macromolecules such as proteins, nucleic acids, viruses and virus components has reached its high degree of effectiveness owing to refinements and reliability of instruments and to the invention of methods for enhancing the structure of these materials within the electron image. The latter techniques have been most important because what can be seen depends upon the molecular and atomic character of the object as modified which is rarely evident in the pristine material. Structure may thus be displayed by the arts of positive and negative staining, shadow casting, replication and other techniques. Enhancement of contrast, which delineates bounds of isolated macromolecules has been effected progressively over the years as illustrated in Figs. 1, 2, 3 and 4 by these methods. We now look to the future wondering what other visions are waiting to be seen. The instrument designers will need to exact from the arts of fabrication the performance that theory has prescribed as well as methods for phase and interference contrast with explorations of the potentialities of very high and very low voltages. Chemistry must play an increasingly important part in future progress by providing specific stain molecules of high visibility, substrates of vanishing “noise” level and means for preservation of molecular structures that usually exist in a solvated condition.

An introduction to the themed issue on RNA biology in China

2020 ◽  
Vol 64 (6) ◽  
pp. 863-866
Author(s):  
Zhe Wu
Keyword(s):  
Molecular Biology ◽  
Chinese Society ◽  
Fortieth Anniversary ◽  
Rna Biology ◽  
Research And Education ◽  
Education In China

Abstract The year 2019 marked the fortieth anniversary of the Chinese Society of Biochemistry and Molecular Biology (CSBMB), whose mission is to promote biomolecular research and education in China. The last 40 years have witnessed tremendous growth and achievements in biomolecular research by Chinese scientists and Essays in Biochemistry is delighted to publish this themed issue that focuses on exciting areas within RNA biology, with each review contributed by key experts from China.

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