scholarly journals Sports Nutrition and Performance

2019 ◽  
Author(s):  
Raúl Arcusa Saura ◽  
María Pilar Zafrilla Rentero ◽  
Javier Marhuenda Hernández
Keyword(s):  
Sports Nutrition ◽  
And Performance

scholarly journals Glutamine as an Anti-Fatigue Amino Acid in Sports Nutrition

Nutrients ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 863 ◽  
Author(s):  
Audrey Yule Coqueiro ◽  
Marcelo Macedo Rogero ◽  
Julio Tirapegui
Keyword(s):  
Amino Acid ◽  
Glycogen Synthesis ◽  
Sports Nutrition ◽  
Glutamine Supplementation ◽  
Inclusion Criteria ◽  
Acid Base Balance ◽  
Ammonia Accumulation ◽  
Pubmed Database ◽  
Base Balance ◽  
And Performance

Glutamine is a conditionally essential amino acid widely used in sports nutrition, especially because of its immunomodulatory role. Notwithstanding, glutamine plays several other biological functions, such as cell proliferation, energy production, glycogenesis, ammonia buffering, maintenance of the acid-base balance, among others. Thus, this amino acid began to be investigated in sports nutrition beyond its effect on the immune system, attributing to glutamine various properties, such as an anti-fatigue role. Considering that the ergogenic potential of this amino acid is still not completely known, this review aimed to address the main properties by which glutamine could delay fatigue, as well as the effects of glutamine supplementation, alone or associated with other nutrients, on fatigue markers and performance in the context of physical exercise. PubMed database was selected to examine the literature, using the keywords combination “glutamine” and “fatigue”. Fifty-five studies met the inclusion criteria and were evaluated in this integrative literature review. Most of the studies evaluated observed that glutamine supplementation improved some fatigue markers, such as increased glycogen synthesis and reduced ammonia accumulation, but this intervention did not increase physical performance. Thus, despite improving some fatigue parameters, glutamine supplementation seems to have limited effects on performance.

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