scholarly journals Heart Failure in Sub-Saharan Africa

2019 ◽  
Author(s):  
Okechukwu S. Ogah ◽  
Adewole Adebiyi ◽  
Karen Sliwa
Keyword(s):  
Heart Failure ◽  
Sub Saharan Africa ◽  
Sub Saharan

Abstract 65: Anemia-related Heart Failure in Sub-saharan African Sickle Cell Disease Patients

2017 ◽  
Vol 121 (suppl_1) ◽  
Author(s):  
Adebayo C Atanda ◽  
Yahya Aliyu ◽  
Oluwafunmilayo Atanda ◽  
Aliyu Babadoko ◽  
Aisha Suleiman ◽  
...  
Keyword(s):  
Heart Failure ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Systolic Pressure ◽  
Left Ventricular ◽  
Hemoglobin Level ◽  
Sub Saharan Africa ◽  
Cell Disease ◽  
Jet Velocity ◽  
Sub Saharan

Introduction: Anemia has been implicated in heart failure. Existing literatures, involving predominantly African-Americans, suggests that Sickle Cell Disease (SCD) maybe linked to various cardiovascular complications including pulmonary hypertension and left venticular dysfunction. Peculiarly, our study involves exclusively Sub-Saharan population. Method: We conducted a cross sectional observational study of 208 hydroxyurea-naive consecutive SCD patients aged 10-52 years at steady state and 94 healthy non-matched controls who were studied in an out patient clinic in Sub-Saharan Africa. SCD patients were required to have electrophoretic or liquid chromatography documentation of major sickling phenotypes. Control group was required to have non-sickling phenotypes. Cardiac measurements were performed with TransThoracic Echo according to American Society of Echocardiography guidelines. Hemoglobin level was also obtained. Results: Hemoglobin level in SCD group (8.5+/- 1.5) was significant (P<0.001) compared to control (13.8+/- 1.7). Although SCD group had significantly higher values of left ventricular (LV) size, there was no qualitative evidence of LV dysfunction. SCD group had higher values of Ejection Fraction but not statistically significant. There was no evidence of LV wall stiffening to impair proper filling in SCD group, with the ratio of early to late ventricular filling velocities, E/A ratio elevated (1.7+/-0.4 compared to 1.6+/- 0.4; P=0.010). Right ventricular systolic pressure was determined using the formula of 4x Tricuspid Reugurgitant jet (TRV) square as an indirect measurement of Pulmonary arterial systolic pressure. SCD patients had significantly higher mean±SD values for tricuspid regurgitant jet velocity than did the controls (2.1±0.6 vs. 1.8±0.5; p= 0.001). Within the SCD group, there was no clear pattern of worsening diastolic function with increased TRV. Furthermore, E/A had a significant positive relationship with jet velocity in bivariate analysis (R=0.20; P=0.013). Conclusions: We were unable to demonstrate existence of anemia-associated left ventricular dysfunction in Sub-Saharan African with SCD. Further studies is required to highlight the reason behind this finding.

scholarly journals Heart failure in sub-Saharan Africa: A clinical approach

2015 ◽  
Vol 106 (1) ◽  
pp. 23 ◽  
Author(s):  
Sarah Kraus ◽  
Gboyega Ogunbanjo ◽  
Karen Sliwa ◽  
Ntobeko A B Ntusi
Keyword(s):  
Heart Failure ◽  
Sub Saharan Africa ◽  
Clinical Approach ◽  
Sub Saharan

scholarly journals Characteristics of patients with acute heart failure in North Central Nigeria

2021 ◽  
Vol 9 (3) ◽  
pp. 221-235
Author(s):  
J.A. Ogunmodede ◽  
P.M. Kolo ◽  
M.O. Bojuwoye ◽  
B.F. Dele-Ojo ◽  
A.J. Ogunmodede ◽  
...  
Keyword(s):  
Heart Failure ◽  
New York ◽  
Heart Association ◽  
Public Health Education ◽  
Sub Saharan Africa ◽  
Aetiological Factor ◽  
Cross Sectional ◽  
Early Presentation ◽  
North Central ◽  
Sub Saharan

Objectives: Heart failure (HF) is an important cause of hospital admission in Nigeria. HF is increasingly prevalent because the population is aging and HF epidemiology is changing. We aimed at profiling the socio-demographic, clinical and echocardiographic (Echo)  characteristics of patients admitted for acute HF. This is one of the largest cohorts of HF patients profiled in Nigeria so far. Methods: Cross sectional design. Socio-demographic, clinical and Echo data were collected from 455 patients admitted for AHF at University of Ilorin Teaching Hospital, North central, Nigeria. Results: Mean age of patients was 58.9± 15.7years, (men were older than women, P= 0.006). 265(58.2%) were males, most patients were aged >60 years, 4.8% had pre-existing Type2 Diabetes mellitus. 53.2% of patients presented in New York Heart Association Stages III and IV. Median duration of admission was 11days (IQR, 6-17), intrahospital mortality- 11.6%. Hypertension was the commonest aetiological factor (62.4%), followed by dilated cardiomyopathy 17.6%, rheumatic heart disease (6.6%), Peripartum cardiomyopathy (5.3%), and others. Conclusion: AHF patients in our study are older than those in previous studies in Nigeria and sub-Saharan Africa. Hypertension is main driver of AHF, and patients largely present with clinically advanced disease necessitating stronger public health education about risk factors and early presentation.  

scholarly journals Prevalence and factors associated with anemia in patients with heart failure in Sub-saharan Africa, Cameroon

2020 ◽  
Vol 12 (1) ◽  
pp. 51-52
Author(s):  
C. Nganou-Gnindjio ◽  
C.A. Pieme ◽  
C. Dongmo Nanfack-Géondo ◽  
D.L. Wouna Angong ◽  
B. Hamadou ◽  
...  
Keyword(s):  
Heart Failure ◽  
Sub Saharan Africa ◽  
Factors Associated ◽  
Patients With Heart Failure ◽  
Sub Saharan

scholarly journals Readmission and death after an acute heart failure event: predictors and outcomes in sub-Saharan Africa: results from the THESUS-HF registry

2013 ◽  
Vol 34 (40) ◽  
pp. 3151-3159 ◽  
Author(s):  
K. Sliwa ◽  
B. A. Davison ◽  
B. M. Mayosi ◽  
A. Damasceno ◽  
M. Sani ◽  
...  
Keyword(s):  
Heart Failure ◽  
Acute Heart Failure ◽  
Sub Saharan Africa ◽  
Heart Failure Event ◽  
Failure Event ◽  
Sub Saharan
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