scholarly journals Infections in Patients with Multiple Myeloma in the Era of Novel Agents and Stem Cell Therapies

Author(s):  
Asma M. Al-Jasser ◽  
Khalid Ahmed Al-Anazi
2014 ◽  
Vol 62 (S 01) ◽  
Author(s):  
M. Arar ◽  
A. Rotärmel ◽  
A.-K. Knoefel ◽  
H. Baraki ◽  
I. Kutschka ◽  
...  

2019 ◽  
Vol 14 (6) ◽  
pp. 454-459
Author(s):  
Xuejing Hou ◽  
Ying Liu ◽  
Isabelle Streuli ◽  
Patrick Dällenbach ◽  
Jean Dubuisson ◽  
...  

Asherman’s Syndrome or Intrauterine adhesions is an acquired uterine condition where fibrous scarring forms within the uterine cavity, resulting in reduced menstrual flow, pelvic pain and infertility. Until recently, the molecular mechanisms leading to the formation of fibrosis were poorly understood, and the treatment of Asherman’s syndrome has largely focused on hysteroscopic resection of adhesions, hormonal therapy, and physical barriers. Numerous studies have begun exploring the molecular mechanisms behind the fibrotic process underlying Asherman’s Syndrome as well as the role of stem cells in the regeneration of the endometrium as a treatment modality. The present review offers a summary of available stem cell-based regeneration studies, as well as highlighting current gaps in research.


2016 ◽  
Vol 5 (2) ◽  
pp. 145-151
Author(s):  
Ana Muñoz ◽  
Víctor Galvez ◽  
María Camarasa

Cancers ◽  
2021 ◽  
Vol 13 (14) ◽  
pp. 3523
Author(s):  
Wancheng Guo ◽  
Haiqin Wang ◽  
Peng Chen ◽  
Xiaokai Shen ◽  
Boxin Zhang ◽  
...  

Multiple myeloma (MM) is a B-cell tumor of the blood system with high incidence and poor prognosis. With a further understanding of the pathogenesis of MM and the bone marrow microenvironment, a variety of adjuvant cell therapies and new drugs have been developed. However, the drug resistance and high relapse rate of MM have not been fundamentally resolved. Studies have shown that, in patients with MM, there is a type of poorly differentiated progenitor cell (MM stem cell-like cells, MMSCs). Although there is no recognized standard for identification and classification, it is confirmed that they are closely related to the drug resistance and relapse of MM. This article therefore systematically summarizes the latest developments in MMSCs with possible markers of MMSCs, introduces the mechanism of how MMSCs work in MM resistance and recurrence, and discusses the active pathways that related to stemness of MM.


Author(s):  
Richard N. Puzzitiello ◽  
Jeremy Dubin ◽  
Mariano E. Menendez ◽  
Michael A. Moverman ◽  
Nicholas R. Pagani ◽  
...  

2017 ◽  
Vol 25 (1) ◽  
pp. 41-49 ◽  
Author(s):  
Aimée C. Colbath ◽  
David D. Frisbie ◽  
Steven W. Dow ◽  
John D. Kisiday ◽  
C. Wayne McIlwraith ◽  
...  

2014 ◽  
Vol 168 (3) ◽  
pp. 328-337 ◽  
Author(s):  
Paola Cipriani ◽  
Piero Ruscitti ◽  
Roberto Giacomelli

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