scholarly journals Novel Techniques in the Surgical Management of Hepatocellular Carcinoma

Liver Cancer ◽  
2018 ◽  
Author(s):  
Vasileia Ntomi ◽  
Anna Paspala ◽  
Dimitrios Schizas
Keyword(s):  
Hepatocellular Carcinoma ◽  
Surgical Management

scholarly journals Changing paradigm in the surgical management of hepatocellular carcinoma with salvage transplantation

HPB ◽  
2016 ◽  
Vol 18 ◽  
pp. e113
Author(s):  
K.W. Ma ◽  
A.C.Y. Chan ◽  
K.S.H. Cho ◽  
S.C. Chan ◽  
C.M. Lo
Keyword(s):  
Hepatocellular Carcinoma ◽  
Surgical Management

Surgical Management of Hepatocellular Carcinoma

2021 ◽  
pp. 1-16
Author(s):  
Duilio Pagano ◽  
Giuseppe Mamone ◽  
Sergio Calamia ◽  
Salvatore Gruttadauria
Keyword(s):  
Hepatocellular Carcinoma ◽  
Surgical Management

scholarly journals Efficacy of External Beam Radiation-Based Treatment plus Locoregional Therapy for Hepatocellular Carcinoma Associated with Portal Vein Tumor Thrombosis

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Ming-Yang Chen ◽  
Yu-Chao Wang ◽  
Tsung-Han Wu ◽  
Chen-Fang Lee ◽  
Ting-Jung Wu ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Portal Vein ◽  
Surgical Management ◽  
External Beam Radiation ◽  
Locoregional Therapy ◽  
Advanced Hepatocellular Carcinoma ◽  
External Beam ◽  
Portal Vein Tumor Thrombosis ◽  
Beam Radiation ◽  
Tumor Thrombosis

Background. Portal vein tumor thrombosis (PVTT) is a common event in advanced hepatocellular carcinoma (HCC). The optimal treatment for these patients remains controversial. Methods. A retrospective review of 149 patients who had unresectable HCC associated with PVTT between January 2005 and December 2012 was performed. Outcomes related to external beam radiation-based treatment were measured, and clinicopathological features and parameters affecting prognosis were analyzed as well. Results. The radiotherapeutic response of PVTT was an important element that affected the overall treatment response of HCC. Serum α-fetoprotein < 400 ng/mL, the presence of a radiotherapeutic response on PVTT, and receiving additional locoregional therapy were significant prognostic factors affecting the survival of patients. Patients who had received additional locoregional therapy obtained a better outcome, and six of them were eventually able to undergo surgical management with curative intent. Conclusion. The outcome of HCC associated with PVTT remains pessimistic. In addition to the current recommended treatment using sorafenib, a combination of external beam radiotherapy targeting PVTT and locoregional therapy for intrahepatic HCC might be a promising strategy for patients who had unresectable HCC with PVTT. This approach could perhaps offer patients a favorable outcome as well as a possible cure with following surgical management.

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