scholarly journals Functioning of the Cardiovascular System of Women in Different Phases of the Ovarian-Menstrual Cycle

2018 ◽  
Author(s):  
Olena Lutsenko
Keyword(s):  
Menstrual Cycle ◽  
Cardiovascular System

scholarly journals Menstrual Cycle Effects on the Neurohumoral and Autonomic Nervous Systems Regulating the Cardiovascular System

2002 ◽  
Vol 87 (4) ◽  
pp. 1569-1575 ◽  
Author(s):  
Nir Hirshoren ◽  
Inna Tzoran ◽  
Igor Makrienko ◽  
Yehuda Edoute ◽  
Mikahl M. Plawner ◽  
...  
Keyword(s):  
Menstrual Cycle ◽  
Cardiovascular System ◽  
Nervous Systems ◽  
Autonomic Nervous

Abstract 446: The Impact of the Menstrual Cycle on the Cardiovascular System

2019 ◽  
Vol 125 (Suppl_1) ◽  
Author(s):  
Chih-Yu Chen ◽  
Chi-Wei Chang ◽  
Sheng-Hung Wang ◽  
Xiang-Yu Xie ◽  
Gin-Chung Wang
Keyword(s):  
Menstrual Cycle ◽  
Cardiovascular System ◽  
The Impact

The Effects of Estradiol on Chronically Damaged Human Fallopian Tubes: A SEM Study

1985 ◽  
Vol 43 ◽  
pp. 648-649
Author(s):  
A. Toledo ◽  
G. Stoelk ◽  
M. Yussman ◽  
R.P. Apkarian
Keyword(s):  
Menstrual Cycle ◽  
Epithelial Cell ◽  
Secretory Cell ◽  
Estrogen Therapy ◽  
Fallopian Tubes ◽  
Cell Surfaces ◽  
Proliferative Phase ◽  
Cyclic Patterns ◽  
Sem Study ◽  
The U.S

Today it is estimated that one of every three women in the U.S. will have problems achieving pregnancy. 20-30% of these women will have some form of oviductal problems as the etiology of their infertility. Chronically damaged oviducts present problems with loss of both ciliary and microvillar epithelial cell surfaces. Estradiol is known to influence cyclic patterns in secretory cell microvilli and tubal ciliogenesis, The purpose of this study was to assess whether estrogen therapy could stimulate ciliogenesis in chronically damaged human fallopian tubes.Tissues from large hydrosalpinges were obtained from six women undergoing tuboplastic repair while in the early proliferative phase of fheir menstrual cycle. In each case the damaged tissue was rinsed in heparinized Ringers-lactate and quartered.

Inflammageing in the cardiovascular system: mechanisms, emerging targets, and novel therapeutic strategies

2020 ◽  
Vol 134 (17) ◽  
pp. 2243-2262
Author(s):  
Danlin Liu ◽  
Gavin Richardson ◽  
Fehmi M. Benli ◽  
Catherine Park ◽  
João V. de Souza ◽  
...  
Keyword(s):  
Cardiovascular Diseases ◽  
Cardiovascular System ◽  
Nlrp3 Inflammasome ◽  
Molecular Mechanisms ◽  
Molecular Targets ◽  
Therapeutic Interventions ◽  
Low Grade ◽  
Cardiovascular Research ◽  
Inflammatory Processes ◽  
Ach Receptors

Abstract In the elderly population, pathological inflammation has been associated with ageing-associated diseases. The term ‘inflammageing’, which was used for the first time by Franceschi and co-workers in 2000, is associated with the chronic, low-grade, subclinical inflammatory processes coupled to biological ageing. The source of these inflammatory processes is debated. The senescence-associated secretory phenotype (SASP) has been proposed as the main origin of inflammageing. The SASP is characterised by the release of inflammatory cytokines, elevated activation of the NLRP3 inflammasome, altered regulation of acetylcholine (ACh) nicotinic receptors, and abnormal NAD+ metabolism. Therefore, SASP may be ‘druggable’ by small molecule therapeutics targeting those emerging molecular targets. It has been shown that inflammageing is a hallmark of various cardiovascular diseases, including atherosclerosis, hypertension, and adverse cardiac remodelling. Therefore, the pathomechanism involving SASP activation via the NLRP3 inflammasome; modulation of NLRP3 via α7 nicotinic ACh receptors; and modulation by senolytics targeting other proteins have gained a lot of interest within cardiovascular research and drug development communities. In this review, which offers a unique view from both clinical and preclinical target-based drug discovery perspectives, we have focused on cardiovascular inflammageing and its molecular mechanisms. We have outlined the mechanistic links between inflammageing, SASP, interleukin (IL)-1β, NLRP3 inflammasome, nicotinic ACh receptors, and molecular targets of senolytic drugs in the context of cardiovascular diseases. We have addressed the ‘druggability’ of NLRP3 and nicotinic α7 receptors by small molecules, as these proteins represent novel and exciting targets for therapeutic interventions targeting inflammageing in the cardiovascular system and beyond.

Cerebral cortical response to rectal distension varies with phases of the menstrual cycle

2001 ◽  
Vol 120 (5) ◽  
pp. A397-A397
Author(s):  
M KERN ◽  
R ARNDORFER ◽  
R COX ◽  
J HYDE ◽  
R SHAKER
Keyword(s):  
Menstrual Cycle ◽  
Cortical Response ◽  
Rectal Distension

1258: Normative Androgens Values Throughout the Menstrual Cycle in Healthy Fertile Women with Normal Sexual Function

2005 ◽  
Vol 173 (4S) ◽  
pp. 341-341
Author(s):  
Andrea Salonia ◽  
Marina Pontillo ◽  
Fabio Fabbri ◽  
Giuseppe Zanni ◽  
Rita Daverio ◽  
...  
Keyword(s):  
Menstrual Cycle ◽  
Sexual Function ◽  
Fertile Women
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