Biosensing Techniques in Yeast: G-Protein Signaling and Protein-Protein Interaction Assays for Monitoring Ligand Stimulation and Oligomer Formation of Heterologous GPCRs

Peripheral Membrane Proteins ◽

10.5772/intechopen.76330 ◽

2018 ◽

Author(s):

Yasuyuki Nakamura ◽

Akihiko Kondo ◽

Jun Ishii

Keyword(s):

G Protein ◽

Protein Interaction ◽

G Protein Signaling ◽

Protein Signaling ◽

Protein Protein Interaction ◽

Oligomer Formation ◽

Ligand Stimulation

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Allosteric Inhibition of the Regulator of G Protein Signaling–Gα Protein–Protein Interaction by CCG-4986

Molecular Pharmacology ◽

10.1124/mol.109.063388 ◽

2010 ◽

Vol 78 (3) ◽

pp. 360-365 ◽

Cited By ~ 31

Author(s):

David L. Roman ◽

Levi L. Blazer ◽

C. Aaron Monroy ◽

Richard R. Neubig

Keyword(s):

G Protein ◽

Protein Interaction ◽

G Protein Signaling ◽

Protein Signaling ◽

Allosteric Inhibition ◽

Protein Protein Interaction

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A Conserved Protein Interaction Interface on the Type 5 G Protein β Subunit Controls Proteolytic Stability and Activity of R7 Family Regulator of G Protein Signaling Proteins

Journal of Biological Chemistry ◽

10.1074/jbc.m110.163600 ◽

2010 ◽

Vol 285 (52) ◽

pp. 41100-41112 ◽

Cited By ~ 13

Author(s):

Morwenna Y. Porter ◽

Keqiang Xie ◽

Edwin Pozharski ◽

Michael R. Koelle ◽

Kirill A. Martemyanov

Keyword(s):

G Protein ◽

Protein Interaction ◽

G Protein Signaling ◽

Signaling Proteins ◽

Protein Signaling ◽

Β Subunit ◽

Interaction Interface ◽

Proteolytic Stability

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High Throughtput Screening Using A Polyplexed Flow Cytometry Protein Interaction Assay (FCPIA) for Small Molecule Inhibitors of Regulator of G protein Signaling (RGS) Proteins

The FASEB Journal ◽

10.1096/fasebj.22.1_supplement.907.2 ◽

2008 ◽

Vol 22 (S1) ◽

Author(s):

David L. Roman ◽

Shodai Ota ◽

Richard R. Neubig ◽

Shodai Ota

Keyword(s):

Flow Cytometry ◽

G Protein ◽

Small Molecule ◽

Protein Interaction ◽

Small Molecule Inhibitors ◽

G Protein Signaling ◽

Rgs Proteins ◽

Protein Signaling

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Regulator of G-Protein Signaling 2

10.32388/nphv4n ◽

2020 ◽

Author(s):

Keyword(s):

G Protein ◽

G Protein Signaling ◽

Protein Signaling

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Faculty Opinions recommendation of Mutation of the regulator of G protein signaling Crg1 increases virulence in Cryptococcus neoformans.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1023154.264841 ◽

2005 ◽

Author(s):

Joseph Heitman

Keyword(s):

Cryptococcus Neoformans ◽

G Protein ◽

G Protein Signaling ◽

Protein Signaling

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Faculty Opinions recommendation of Functional selectivity of G protein signaling by agonist peptides and thrombin for the protease-activated receptor-1.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1025784.305777 ◽

2005 ◽

Author(s):

Rodger Loutzenhiser

Keyword(s):

G Protein ◽

G Protein Signaling ◽

Protein Signaling ◽

Functional Selectivity ◽

Protease Activated Receptor 1

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Faculty Opinions recommendation of Signaling by a non-dissociated complex of G protein βγ and α subunits stimulated by a receptor-independent activator of G protein signaling, AGS8.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1083787.536710 ◽

2007 ◽

Author(s):

Carmen Dessauer

Keyword(s):

G Protein ◽

G Protein Signaling ◽

Protein Signaling ◽

Α Subunits

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Faculty Opinions recommendation of Heterotrimeric G protein signaling functions with dynein to promote spindle positioning in C. elegans.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1092303.546718 ◽

2007 ◽

Author(s):

Bob Goldstein

Keyword(s):

G Protein ◽

G Protein Signaling ◽

Protein Signaling ◽

Heterotrimeric G Protein ◽

Spindle Positioning ◽

C Elegans ◽

Heterotrimeric G Protein Signaling

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Faculty Opinions recommendation of Suppression of immunoglobulin E-mediated allergic responses by regulator of G protein signaling 13.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1098073.553501 ◽

2007 ◽

Author(s):

Thomas Wynn

Keyword(s):

G Protein ◽

Immunoglobulin E ◽

G Protein Signaling ◽

Protein Signaling

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Faculty Opinions recommendation of Reversible, allosteric small-molecule inhibitors of regulator of G protein signaling proteins.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.3767956.3494054 ◽

2010 ◽

Author(s):

Stephen Schwartz

Keyword(s):

G Protein ◽

Small Molecule ◽

Small Molecule Inhibitors ◽

G Protein Signaling ◽

Signaling Proteins ◽

Protein Signaling

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