scholarly journals Chemotherapy of Cholangiocarcinoma: Current Management and Future Directions

2018 ◽  
Author(s):  
Jung Hyun Jo ◽  
Si Young Song
Keyword(s):  
Current Management ◽  
Future Directions

scholarly journals Recent advances in understanding necrotizing enterocolitis

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 107 ◽  
Author(s):  
Mashriq Alganabi ◽  
Carol Lee ◽  
Edoardo Bindi ◽  
Bo Li ◽  
Agostino Pierro
Keyword(s):  
Risk Factors ◽  
Preterm Infants ◽  
Necrotizing Enterocolitis ◽  
Advanced Disease ◽  
Current Understanding ◽  
Disease Development ◽  
Current Management ◽  
Future Directions ◽  
Ongoing Research ◽  
Factors Associated

Necrotizing enterocolitis is a devastating intestinal disease affecting preterm infants. In spite of ongoing research and advancement in neonatal care, mortality remains high, especially in infants with advanced disease. The mechanism of disease development, the progression of intestinal injury, and management remain areas of ongoing research and controversy. In this review, we examine our current understanding of the disease, its epidemiology, the risk factors associated with the development of the disease, and its pathophysiology. We also describe current management and new emerging research highlighting potential future directions.

Current Management of Refractory Germ Cell Tumors and Future Directions

2017 ◽  
Vol 19 (2) ◽  
Author(s):  
J. Clayton Allen ◽  
Austin Kirschner ◽  
Kristen R. Scarpato ◽  
Alicia K. Morgans
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumors ◽  
Current Management ◽  
Future Directions

Article Commentary: Medullary Thyroid Cancer: An Update for Surgeons

2015 ◽  
Vol 81 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Faris K. Azar ◽  
Stephanie L. Lee ◽  
Jennifer E. Rosen
Keyword(s):  
Thyroid Cancer ◽  
Thyroid Carcinoma ◽  
Medullary Thyroid Carcinoma ◽  
Progressive Disease ◽  
Medullary Thyroid Cancer ◽  
Germline Mutations ◽  
Current Management ◽  
Future Directions ◽  
Medullary Thyroid ◽  
Individualized Management

Medullary thyroid carcinoma is uncommon but accounts for approximately 4 to 5 per cent of all thyroid cancers. Although most cases are sporadic, close to one-fourth of cases result from germline mutations in the RET proto-oncogene. These mutations are clinically important because they predict the earliest age of medullary thyroid cancer diagnosis and clinical aggressiveness, which guide individualized management. This review covers the presentation, diagnosis, workup, current management, and future directions of the management of medullary thyroid carcinoma. Today's chance for cure depends on early and appropriate surgical resection. Further investigation of the cellular signaling pathways shown to be essential for the growth and spread of medullary thyroid carcinoma remains an active field with hope for providing targeted systemic therapy for patients with progressive disease.

Extracranial oligometastatic renal cell carcinoma: current management and future directions

2014 ◽  
Vol 10 (5) ◽  
pp. 761-774 ◽  
Author(s):  
Jasmin Loh ◽  
Ian D Davis ◽  
Jarad M Martin ◽  
Shankar Siva
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Current Management ◽  
Future Directions
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