scholarly journals Management of Brain Metastases from Solid Tumors

Author(s):  
Roman Liubota ◽  
Roman Vereshchako ◽  
Mykola Anikusko ◽  
Iryna Liubota
Author(s):  
Alessandra Fabi ◽  
Alessandra Felici ◽  
Giulio Metro ◽  
Alessandra Mirri ◽  
Emilio Bria ◽  
...  

2020 ◽  
Vol 9 (7) ◽  
pp. 2299-2308
Author(s):  
Jinling Jiang ◽  
Lihong Wu ◽  
Fei Yuan ◽  
Jun Ji ◽  
Xiaojing Lin ◽  
...  

2020 ◽  
Vol 2 (Supplement_2) ◽  
pp. ii14-ii14
Author(s):  
Clarissa Aguilar ◽  
Víctor Toro ◽  
Rina Medina

Abstract BACKGROUND 80% of childhood cancer are located in low- and middle-income countries (LMIC). The most common form of presentation is disseminated or metastatic disease. The rate of survival has not been equitable across the world, since in these countries only 1 of 5 children are cured. OBJECTIVE To evaluate the clinical and histopathological features of patients with metastatic pediatric solid tumors, in a single referral cancer center in Honduras. METHODS We conducted a retrospective review of patients diagnosed with pediatric solid tumors from January 2010 to April 2020. Among the 260 patients through a collection form, we obtained: sociodemographic characteristics, clinical presentation at diagnosis, common histological subtypes, sites of metastasis, treatment and outcome at the time of follow-up. RESULTS During the last 10 years, 260 cases of childhood cancer were referred to our center for treatment. 127 patients (48.8%), have a solid tumor, patients ranged in age from 1 to 18 years and distribution for sex were 38% for males and 62% females. At the time of initial diagnosis 40/127 (31%) have advanced disease (stages III and IV). We found brain metastases in 22/40 cases (55%), the primary cancer was localized at CNS in 13/22 (59%) and the most common extracranial tumors causing brain metastases were neuroblastoma (4/22), rhabdomyosarcoma (3/22), retinoblastoma (2/22). Currently in the follow-up there were 18/22 (82%) died and 4/22 (18%) are in treatment with palliative intent. CONCLUSION There is a lack of information about the epidemiology of brain metastases among children with solid tumors in the low/middle income countries (LMIC) where the prognosis of metastatic disease is very poor, despite efforts, multimodal therapy and multidisciplinary management, in absence of other options like bone marrow transplantation, and reliable access to high-quality medicines. For our countries, timely diagnosis is still the main determining factor for cure.


2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 8186-8186 ◽  
Author(s):  
S. Evans ◽  
N. Jooma ◽  
A. Kabir ◽  
L. Nedzi ◽  
E. Zakris ◽  
...  

2006 ◽  
Vol 10 (3) ◽  
pp. 395-401 ◽  
Author(s):  
Iver Petersen ◽  
Alfredo Hidalgo ◽  
Simone Petersen ◽  
Karsten Schlüns ◽  
Christiane Schewe ◽  
...  

Onkologie ◽  
2019 ◽  
Vol 13 (4) ◽  
pp. 167-172
Author(s):  
Tomáš Kazda ◽  
Radek Lakomý ◽  
Petr Pospíšil ◽  
Ludmila Hynková ◽  
Jiří Šána ◽  
...  

2018 ◽  
Vol 1 (1) ◽  
pp. 28-40
Author(s):  
R.V. Liubota ◽  
R.I. Vereschako ◽  
M.F. Anikusko ◽  
I.I. Liubota ◽  
Ya.M. Prykhodko

2018 ◽  
Vol 20 (suppl_6) ◽  
pp. vi55-vi55
Author(s):  
Catherine Garcia ◽  
Stacey Slone ◽  
William St Clair ◽  
Eric Durbin ◽  
Thomas Pittman ◽  
...  

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