scholarly journals An Overview on Prostate Pathophysiology: New Insights into Prostate Cancer Clinical Diagnosis

Author(s):  
Gustavo Ferreira Simoes ◽  
Paula Sakuramoto ◽  
Caroline Brito dos Santos ◽  
Nilva Karla Cervigne Furlan ◽  
Taize Machado Augusto
Oncotarget ◽  
2017 ◽  
Vol 9 (1) ◽  
pp. 428-441 ◽  
Author(s):  
Libo Xu ◽  
Jinguo Wang ◽  
Baofeng Guo ◽  
Haixia Zhang ◽  
Kaichen Wang ◽  
...  

2015 ◽  
Vol 18 (2) ◽  
pp. 61 ◽  
Author(s):  
MichaelEmeka Onwukamuche ◽  
ChilotaChibuife Efobi ◽  
IgwebuikeVictor Onyiaorah ◽  
CorneliusOzobia Ukah ◽  
DanielChukwuemeka Anyiam

2019 ◽  
Author(s):  
Daniel O. Erim ◽  
Jeannette T. Bensen ◽  
James L. Mohler ◽  
Elizabeth T. H. Fontham ◽  
Lixin Song ◽  
...  

2020 ◽  
Vol 65 (1) ◽  
pp. 87-98
Author(s):  
Qi Zhang ◽  
Jingyu Xiong ◽  
Yehua Cai ◽  
Jun Shi ◽  
Shugong Xu ◽  
...  

AbstractB-mode ultrasonography and sonoelastography are used in the clinical diagnosis of prostate cancer (PCa). A combination of the two ultrasound (US) modalities using computer aid may be helpful for improving the diagnostic performance. A technique for computer-aided diagnosis (CAD) of PCa is presented based on multimodal US. Firstly, quantitative features are extracted from both B-mode US images and sonoelastograms, including intensity statistics, regional percentile features, gray-level co-occurrence matrix (GLCM) texture features and binary texture features. Secondly, a deep network named PGBM-RBM2 is proposed to learn and fuse multimodal features, which is composed of the point-wise gated Boltzmann machine (PGBM) and two layers of the restricted Boltzmann machines (RBMs). Finally, the support vector machine (SVM) is used for prostatic disease classification. Experimental evaluation was conducted on 313 multimodal US images of the prostate from 103 patients with prostatic diseases (47 malignant and 56 benign). Under five-fold cross-validation, the classification sensitivity, specificity, accuracy, Youden’s index and area under the receiver operating characteristic (ROC) curve with the PGBM-RBM2 were 87.0%, 88.8%, 87.9%, 75.8% and 0.851, respectively. The results demonstrate that multimodal feature learning and fusion using the PGBM-RBM2 can assist in the diagnosis of PCa. This deep network is expected to be useful in the clinical diagnosis of PCa.


Author(s):  
Laura Dumont ◽  
Adriano Salaroli ◽  
Lissandra Dal Lago ◽  
Thierry Gil ◽  
Thierry Pepersack

We report the case of a 76-year-old man presenting with reactive haemophagocytic lymphohistiocytosis (rHLH) in the setting of disseminated prostate cancer. This often fatal syndrome must be diagnosed early in order to maximize survival. Treatment should be initiated whenever the clinical diagnosis is suspected, even if the HLH-2004 criteria are not met. The HScore is a useful diagnostic tool for rHLH. In case of neurological symptoms, an extensive assessment must be performed. The goal of this case report is to raise awareness of this rare syndrome among oncologists.


Sign in / Sign up

Export Citation Format

Share Document