scholarly journals Gender Differences in Frontotemporal Lobar Degeneration (FTLD) Support an Estrogenic Model of Delayed Onset

Author(s):  
Claire V. Flaherty ◽  
Arghavan S. Zangeneh ◽  
Marissa A. Harrison ◽  
Sanjana Marikunte
Author(s):  
Raksha Anand ◽  
John Hart ◽  
Patricia S. Moore ◽  
Sandra B. Chapman

Abstract Purpose: Frontotemporal lobar degeneration (FTLD) encompasses a group of neurodegenerative disorders characterized by gradual and progressive decline in behavior and/or language. Identifying the subtypes of FTLD can be challenging with traditional assessment tools. Growing empirical evidence suggests that language measures might be useful in differentiating FTLD subtypes. Method: In this paper, we examined the performance of five individuals with FTLD (two with frontotemporal dementia, two with semantic dementia, and one with progressive nonfluent aphasia) and 10 cognitively normal older adults on measures of semantic binding (Semantic Object Retrieval Test and semantic problem solving) and abstracted meaning (generation of interpretive statement and proverb interpretation). Results and Conclusion: A differential profile of impairment was observed in the three FTLD subtypes on these four measures. Further examination of these measures in larger groups will establish their clinical utility in differentiating the FTLD subtypes.


2006 ◽  
Vol 5 (1) ◽  
pp. 30-31
Author(s):  
C ZUGCK ◽  
A FLUEGEL ◽  
L FRANKENSTEIN ◽  
M NELLES ◽  
M HAASS ◽  
...  

VASA ◽  
2018 ◽  
Vol 47 (4) ◽  
pp. 267-272 ◽  
Author(s):  
Konstanze Stoberock ◽  
Tilo Kölbel ◽  
Gülsen Atlihan ◽  
Eike Sebastian Debus ◽  
Nikolaos Tsilimparis ◽  
...  

Abstract. This article analyses if and to what extent gender differences exist in abdominal aortic aneurysm (AAA) therapy. For this purpose Medline (PubMed) was searched from January 1999 to January 2018. Keywords were: “abdominal aortic aneurysm”, “gender”, “prevalence”, “EVAR”, and “open surgery of abdominal aortic aneurysm”. Regardless of open or endovascular treatment of abdominal aortic aneurysms, women have a higher rate of complications and longer hospitalizations compared to men. The majority of studies showed that women have a lower survival rate for surgical and endovascular treatment of abdominal aneurysms after both elective and emergency interventions. Women receive less surgical/interventional and protective medical treatment. Women seem to have a higher risk of rupture, a lower survival rate in AAA, and a higher rate of complications, regardless of endovascular or open treatment. The gender differences may be due to a higher age of women at diagnosis and therapy associated with higher comorbidity, but also because of genetic, hormonal, anatomical, biological, and socio-cultural differences. Strategies for treatment in female patients must be further defined to optimize outcome.


2000 ◽  
Vol 16 (3) ◽  
pp. 147-149 ◽  
Author(s):  
Martin Grann

Summary: Hare's Psychopathy Checklist - Revised (PCL-R; Hare, 1991 ) was originally constructed for use among males in correctional and forensic settings. In this study, the PCL-R protocols of 36 matched pairs of female and male violent offenders were examined with respect to gender differences. The results indicated a few significant differences. By means of discriminant analysis, male Ss were distinguished from their female counterparts through their relatively higher scores on “callous/lack of empathy” (item 8) and “juvenile delinquency” (item 18), whereas the female Ss scored relatively higher on “promiscuous sexual behavior” (item 11). Some sources of bias and possible implications are discussed.


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