scholarly journals Pathogenomics and Molecular Advances in Pathogen Identification

2018 ◽  
Author(s):  
Rosa Estela Quiroz-Castañeda
Keyword(s):  
Pathogen Identification

scholarly journals Fish Pathology Research and Diagnosis in Aquaculture of Farmed Fish; a Proteomics Perspective

Animals ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 125
Author(s):  
Márcio Moreira ◽  
Denise Schrama ◽  
Ana Paula Farinha ◽  
Marco Cerqueira ◽  
Cláudia Raposo de Magalhães ◽  
...  
Keyword(s):  
Climate Changes ◽  
Holistic Approach ◽  
Disease Outbreak ◽  
External Factors ◽  
Pathogen Identification ◽  
Farmed Fish ◽  
Disease Research ◽  
Fish Pathology ◽  
Important Characterization ◽  
Aquaculture Production

One of the main constraints in aquaculture production is farmed fish vulnerability to diseases due to husbandry practices or external factors like pollution, climate changes, or even the alterations in the dynamic of product transactions in this industry. It is though important to better understand and characterize the intervenients in the process of a disease outbreak as these lead to huge economical losses in aquaculture industries. High-throughput technologies like proteomics can be an important characterization tool especially in pathogen identification and the virulence mechanisms related to host-pathogen interactions on disease research and diagnostics that will help to control, prevent, and treat diseases in farmed fish. Proteomics important role is also maximized by its holistic approach to understanding pathogenesis processes and fish responses to external factors like stress or temperature making it one of the most promising tools for fish pathology research.

Facile syringe filter-enabled bacteria separation, enrichment, and buffer exchange for clinical isolation-free digital detection and characterization of bacterial pathogens in urine

The Analyst ◽  
2021 ◽  
Author(s):  
Pengfei Zhang ◽  
Aniruddha Kaushik ◽  
Kathleen E Mach ◽  
Kuangwen Hsieh ◽  
Joseph C. Liao ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
Antibiotic Therapy ◽  
Broad Spectrum ◽  
Antimicrobial Susceptibility ◽  
Susceptibility Testing ◽  
Evidence Based ◽  
Pathogen Identification ◽  
Accelerated Methods ◽  
Syringe Filter

The development of accelerated methods for pathogen identification (ID) and antimicrobial susceptibility testing (AST) for infectious diseases is necessary to facilitate evidence-based antibiotic therapy and reduce clinical overreliance on broad-spectrum...

scholarly journals A surface topography assisted droplet manipulation platform for biomarker detection and pathogen identification

Lab on a Chip ◽  
2011 ◽  
Vol 11 (3) ◽  
pp. 398-406 ◽  
Author(s):  
Yi Zhang ◽  
Seungkyung Park ◽  
Kelvin Liu ◽  
Jennifer Tsuan ◽  
Samuel Yang ◽  
...  
Keyword(s):  
Surface Topography ◽  
Biomarker Detection ◽  
Pathogen Identification ◽  
Droplet Manipulation

Multiplex-direct PCR assay for foodborne pathogen identification: An application in forensic investigation

2013 ◽  
Vol 4 (1) ◽  
pp. e103-e104 ◽  
Author(s):  
Laila Hasap ◽  
Phuvadol Thanakiatkrai ◽  
Kamonnut Singkhamanan ◽  
Adrian Linacre ◽  
Thitika Kitpipit
Keyword(s):  
Foodborne Pathogen ◽  
Forensic Investigation ◽  
Pathogen Identification ◽  
Pcr Assay ◽  
Direct Pcr

scholarly journals 48. Association of Rapid Pathogen Identification and Pharmacist Intervention on Time to Optimal Antimicrobial Therapy for Bloodstream Infections at Two Community Hospitals

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S47-S47
Author(s):  
Bryant M Froberg ◽  
Nicholas Torney
Keyword(s):  
Blood Culture ◽  
Hospital Mortality ◽  
Positive Blood Culture ◽  
Antimicrobial Therapy ◽  
Length Of Hospital Stay ◽  
Bloodstream Infections ◽  
Pharmacist Intervention ◽  
Pathogen Identification ◽  
Community Hospitals ◽  
Significant Difference

Abstract Background As many as 1 in 3 patients with bloodstream infections at community hospitals receive inappropriate empiric antimicrobial therapy. Studies have shown that the coupling of real-time intervention with rapid pathogen identification improves patient outcomes and decreases health-system costs at large, tertiary academic centers. The aim of this study was to assess if similar outcomes could be obtained with the implementation of real-time pharmacist intervention to rapid pathogen identification at two smaller, rural community hospitals. Methods This was a pre-post implementation study that occurred from September of 2019 to March 2020. This study included patients ≥18 years of age admitted with one positive blood culture. Patients were excluded if they were pregnant, had a polymicrobial blood culture, known culture prior to admission, hospice consulted prior to admission, expired prior to positive blood culture, or transferred to another hospital within 24 hours of a positive blood culture. Endpoints of patients prior to intervention were compared to patients post-implementation. The primary endpoint was time to optimal antimicrobial therapy. Secondary endpoints included time to effective antimicrobial therapy, in-hospital mortality, length of hospital stay, and overall cost of hospitalization. Results Of 212 patients screened, 88 patients were included with 44 patients in each group. Both groups were similar in terms of comorbidities, infection source, and causative microbial. No significant difference was seen in the mean time to optimal antimicrobial therapy (27.3±35.5 hr vs 19.4± 30 hr, p=0.265). Patients in the post-implementation group had a significantly higher mean hospitalization cost ($24,638.87± $11,080.91 vs $32,722.07±$13,076.73, p=0.013). There was no significant difference in time to effective antimicrobial therapy, in-hospital mortality, or length of hospital stay. Conclusion There were no between-group differences in the primary outcome of time to optimal therapy, with a higher mean hospitalization cost after implementation. These results suggest further antimicrobial stewardship interventions are needed, along with larger studies conducted in the community hospital settings. Disclosures All Authors: No reported disclosures

scholarly journals Educational Case: Staphylococcus aureus Bacteremia: Utilization of Rapid Diagnostics for Bloodstream Pathogen Identification and Prediction of Antimicrobial Susceptibility

2021 ◽  
Vol 8 ◽  
pp. 237428952110153
Author(s):  
Carlos A. Castrodad-Rodríguez ◽  
Erika P. Orner ◽  
Wendy A. Szymczak
Keyword(s):  
Organ System ◽  
Learning Objectives ◽  
National Standards ◽  
Rapid Diagnostics ◽  
Pathogen Identification ◽  
Full List ◽  
Additional Information ◽  
Staphylococcus Aureus Bacteremia ◽  
Disease Mechanisms ◽  
Basic Competencies

The following fictional case is intended as a learning tool within the Pathology Competencies for Medical Education (PCME), a set of national standards for teaching pathology. These are divided into three basic competencies: Disease Mechanisms and Processes, Organ System Pathology, and Diagnostic Medicine and Therapeutic Pathology. For additional information, and a full list of learning objectives for all three competencies, see http://journals.sagepub.com/doi/10.1177/2374289517715040 . 1

scholarly journals Pathogen Identification Direct From Polymicrobial Specimens Using Membrane Glycolipids

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
William E. Fondrie ◽  
Tao Liang ◽  
Benjamin L. Oyler ◽  
Lisa M. Leung ◽  
Robert K. Ernst ◽  
...  
Keyword(s):  
Pathogen Identification

scholarly journals Rapid pathogen identification using a novel microarray-based assay with purulent meningitis in cerebrospinal fluid

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Yuting Hou ◽  
Xu Zhang ◽  
Xiaolin Hou ◽  
Ruofen Wu ◽  
Yanbai Wang ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Pathogen Identification ◽  
Purulent Meningitis

scholarly journals Real-Time Automated Pathogen Identification by Enhanced Ribotyping (RAPIER) LDRD Final Report

2018 ◽  
Author(s):  
Michael S. Bartsch ◽  
Sara Bird ◽  
Steven Branda ◽  
Harrison Edwards ◽  
Harikrishnan Jayamohan ◽  
...  
Keyword(s):  
Real Time ◽  
Final Report ◽  
Pathogen Identification
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