scholarly journals Antibacterial Activity of Metallic Nanoparticles

2018 ◽  
Author(s):  
Shamaila Shahzadi ◽  
Nosheen Zafar ◽  
Rehana Sharif
Keyword(s):  
Antibacterial Activity ◽  
Metallic Nanoparticles

scholarly journals Chitosan-Stabilized Ag Nanoparticles with Superior Biocompatibility and Their Synergistic Antibacterial Effect in Mixtures with Essential Oils

Nanomaterials ◽  
2018 ◽  
Vol 8 (10) ◽  
pp. 826 ◽  
Author(s):  
Ludmila Cinteza ◽  
Cristina Scomoroscenco ◽  
Sorina Voicu ◽  
Cristina Nistor ◽  
Sabina Nitu ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Essential Oils ◽  
Metallic Nanoparticles ◽  
Synergistic Effects ◽  
Medical Application ◽  
Colloidal Dispersion ◽  
Multidrug Resistant ◽  
Antimicrobial Activities ◽  
Promising Alternative

Silver nanoparticles (AgNPs) are considered a promising alternative to the use of antibiotics in fighting multidrug-resistant pathogens. However, their use in medical application is hindered by the public concern regarding the toxicity of metallic nanoparticles. In this study, rationally designed AgNP were produced, in order to balance the antibacterial activity and toxicity. A facile, environmentally friendly synthesis was used for the electrochemical fabrication of AgNPs. Chitosan was employed as the capping agent, both for the stabilization and to improve the biocompatibility. Size, morphology, composition, capping layer, and stability of the synthesized nanoparticles were characterized. The in vitro biocompatibility and antimicrobial activities of AgNPs against common Gram-negative and Gram-positive bacteria were evaluated. The results revealed that chitosan-stabilized AgNPs were nontoxic to normal fibroblasts, even at high concentrations, compared to bare nanoparticles, while significant antibacterial activity was recorded. The silver colloidal dispersion was further mixed with essential oils (EO) to increase the biological activity. Synergistic effects at some AgNP–EO ratios were observed, as demonstrated by the fractionary inhibitory concentration values. Our results reveal that the synergistic action of both polymer-stabilized AgNPs and essential oils could provide a significant efficiency against a large variety of microorganisms, with minimal side effects.

scholarly journals Investigation of Nanoparticle Metallic Core Antibacterial Activity: Gold and Silver Nanoparticles against Escherichia coli and Staphylococcus aureus

2021 ◽  
Vol 22 (4) ◽  
pp. 1905
Author(s):  
Jimmy Gouyau ◽  
Raphaël E. Duval ◽  
Ariane Boudier ◽  
Emmanuel Lamouroux
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Silver Nanoparticles ◽  
Antibacterial Activity ◽  
Metallic Nanoparticles ◽  
Catalytic Reduction ◽  
Gold And Silver Nanoparticles ◽  
High Antibacterial Activity ◽  
Vis Spectroscopy ◽  
Broth Microdilution Method

Multidrug-resistant (MDR) bacteria constitute a global health issue. Over the past ten years, interest in nanoparticles, particularly metallic ones, has grown as potential antibacterial candidates. However, as there is no consensus about the procedure to characterize the metallic nanoparticles (MNPs; i.e., metallic aggregates) and evaluate their antibacterial activity, it is impossible to conclude about their real effectiveness as a new antibacterial agent. To give part of the answer to this question, 12 nm gold and silver nanoparticles have been prepared by a chemical approach. After their characterization by transmission electronic microscopy (TEM), Dynamic Light Scattering (DLS), and UltraViolet-visible (UV-vis) spectroscopy, their surface accessibility was tested through the catalytic reduction of the 4-nitrophenol, and their stability in bacterial culture medium was studied. Finally, the antibacterial activities of 12 nm gold and silver nanoparticles facing Staphylococcus aureus and Escherichia coli have been evaluated using the broth microdilution method. The results show that gold nanoparticles have a weak antibacterial activity (i.e., slight inhibition of bacterial growth) against the two bacteria tested. In contrast, silver nanoparticles have no activity on S. aureus but demonstrate a high antibacterial activity against Escherichia coli, with a minimum inhibitory concentration of 128 µmol/L. This high antibacterial activity is also maintained against two MDR-E. coli strains.

scholarly journals Biosynthesis of zinc oxide nanoparticles by using fruits extracts of Ananas Comosus and its antibacterial activity

2019 ◽  
Vol 15 (2) ◽  
pp. 268-273 ◽  
Author(s):  
Raja Adibah Raja Ahmad ◽  
Zawati Harun ◽  
Mohd Hafiz Dzarfan Othman ◽  
Hatijah Basri ◽  
Muhamad Zaini Yunos ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Antibacterial Activity ◽  
Zno Nanoparticles ◽  
Zinc Oxide Nanoparticles ◽  
Metallic Nanoparticles ◽  
Ananas Comosus ◽  
Biological Synthesis ◽  
Diffusion Method ◽  
Oxide Nanoparticles ◽  
X Ray

Biosynthesis of metallic nanoparticles using plants, enzymes, and microorganism have been known as eco-friendly alternatives to conventional physical and chemical methods. Recently, the biological synthesis of nanoparticles has been a keen interest amongst researchers and scientist due to its simple technique, eco-friendliness, non-toxic, inexpensive and potential to perform in antibacterial activity. Thus, in this current work, the synthesis of zinc oxide (ZnO) nanoparticles using reduction agent from fruit extracts of Ananas Comosus is reported. The biosynthesized zinc oxide was characterized using Field Emission Scanning Electron Microscope (FESEM) with Energy Dispersive X-ray analysis (EDX), UV-Vis absorption spectroscopy and X-ray diffraction (XRD). The average size of the nanoparticles was found to be in the range of 30-57nm. The antibacterial activity of ZnO nanoparticles was carried out via agar diffusion method against pathogenic organisms. It is observed that the biosynthesized ZnO in the process has the efficient antibacterial activity. In conclusion, the green synthesis of zinc oxide nanoparticles using the fruit extract of Ananas Comosus is considered as a potential additive to substitute other metal oxides such as silver (Ag) and titanium dioxide (TiO2)but also provide antibacterial effect that able to enhance the nanoparticle performance.

scholarly journals Antibacterial Activity of Green Synthesis of Iron Nanoparticles UsingLawsonia inermisandGardenia jasminoidesLeaves Extract

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Tayyaba Naseem ◽  
Muhammad Akhyar Farrukh
Keyword(s):  
Electron Microscopy ◽  
Antibacterial Activity ◽  
Green Synthesis ◽  
Metal Nanoparticles ◽  
Metallic Nanoparticles ◽  
Iron Nanoparticles ◽  
Conventional Heating ◽  
Diffusion Method ◽  
Gravimetric Analysis ◽  
Lawsonia Inermis

Recently, development of reliable experimental protocols for synthesis of metal nanoparticles with desired morphologies and sizes has become a major focus of researchers. Green synthesis of metallic nanoparticles has accumulated an ultimate interest over the last decade due to their distinctive properties that make them applicable in various fields of science and technology. Metal nanoparticles that are synthesized by using plants have emerged as nontoxic and ecofriendly. In this study a very cheap and simple conventional heating method was used to obtain the iron nanoparticles (FeNPs) using the leaves extract ofLawsonia inermisandGardenia jasminoidesplant. The iron nanoparticles were characterized by thermal gravimetric analysis (TGA), Fourier transform infrared spectroscopy (FT-IR), transmission electron microscopy (TEM), scanning electron microscopy (SEM), atomic force microscopy (AFM), and X-ray diffraction (XRD). The antibacterial activity was studied againstEscherichia coli,Salmonella enterica,Proteus mirabilis, andStaphylococcus aureusby using well-diffusion method.

scholarly journals Coating of Polyetheretherketone Films with Silver Nanoparticles by a Simple Chemical Reduction Method and Their Antibacterial Activity

Coatings ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 91 ◽  
Author(s):  
Andrés Cruz-Pacheco ◽  
Deysi Muñoz-Castiblanco ◽  
Jairo Gómez Cuaspud ◽  
Leonel Paredes-Madrid ◽  
Carlos Parra Vargas ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Antibacterial Activity ◽  
Metallic Nanoparticles ◽  
Chemical Reduction ◽  
Single Layer ◽  
Polymeric Substrate ◽  
Chemical Route ◽  
Force Microscopy ◽  
Transmission Electron ◽  
Cellular Replication

The coating of polymeric substrate polyetheretherketone (PEEK) with silver nanoparticles (AgNPs) was carried out by a wet chemical route at room temperature. The coating process was developed from the Tollens reagent and D-glucose as reducing agent. The resulting composite exhibited antimicrobial activity. The PEEK films were coated with a single layer and two layers of silver nanoparticles in various concentrations. The crystallographic properties of the polymer and the silver nanoparticles were analyzed by X-ray diffraction (XRD). Fourier transform infrared spectra (FTIR) show the interaction between the silver nanoparticles with the polymeric substrate. Transmission electron microscope (TEM) images confirmed the obtaining of metallic nanoparticles with average sizes of 25 nm. It was possible to estimate the amount of silver deposited on PEEK with the help of thermogravimetric analysis. The morphology and shape of the AgNPs uniformly deposited on the PEEK films was ascertained by the techniques of scanning electron microscopy (SEM) and atomic force microscopy (AFM), evidencing the increase in the amount of silver by increasing the concentration of the metal precursor. Finally, the antibacterial activity of the films coated with Ag in Escherichia coli, Serratia marcescens and Bacillus licheniformis was evaluated, evidencing that the concentration of silver is crucial in the cellular replication of the bacteria.

scholarly journals Noble metallic nanoparticles from waste Nypa fruticans fruit husk: Biosynthesis, characterization, antibacterial activity and recyclable catalysis

2020 ◽  
Vol 13 (10) ◽  
pp. 7490-7503
Author(s):  
Van-Dat Doan ◽  
Minh-Tan Phung ◽  
Thi Lan-Huong Nguyen ◽  
Thanh-Chi Mai ◽  
Thanh-Danh Nguyen
Keyword(s):  
Antibacterial Activity ◽  
Metallic Nanoparticles ◽  
Nypa Fruticans

scholarly journals Recent Advances in Chitosan-Based Metal Nanocomposites for Wound Healing Applications

2020 ◽  
Vol 2020 ◽  
pp. 1-13
Author(s):  
Kai Wang ◽  
Su Pan ◽  
Zhiping Qi ◽  
Peng Xia ◽  
Haotian Xu ◽  
...  
Keyword(s):  
Wound Healing ◽  
Antibacterial Activity ◽  
Mechanical Strength ◽  
Metallic Nanoparticles ◽  
Wound Repair ◽  
Antibacterial Properties ◽  
Collagen Deposition ◽  
Natural Polymer ◽  
Biological Affinity ◽  
Metal Nanocomposites

Chitosan (CS) has been extensively studied as a natural polymer, in the field of wound repair, due to its useful properties, which include a lack of toxicity and stimulation, excellent biological affinity, degradability, and promotion of collagen deposition. However, inferior mechanical strength and moderate antibacterial properties are the drawbacks restricting its further clinical application. Many researchers have adopted the use of nanotechnology, in particular metallic nanoparticles (MNPs), in order to improve the mechanical strength and specific antibacterial properties of chitosan composites, with promising results. Furthermore, chitosan naturally functions as a reducing agent for MNPs, which can also reduce cytotoxicity. Thus, CS, in combination with MNPs, exhibits antibacterial activity, excellent mechanical strength, and anti-inflammatory properties, and it has great potential to accelerate the process of wound healing. This review discusses the current use of CS and MNPs in wound healing and emphasises the synergy and the advantages for various applications in wound healing.

Evaluation of the Antibacterial Activity of Ag- and Au-Nanoparticles Loaded TiO2 Nanotubes

2020 ◽  
Vol 16 (9) ◽  
pp. 1416-1425
Author(s):  
Katarzyna Arkusz ◽  
Ewa Paradowska ◽  
Marta Nycz ◽  
Justyna Mazurek-Popczyk ◽  
Katarzyna Baldy-Chudzik
Keyword(s):  
Gold Nanoparticles ◽  
Antibacterial Activity ◽  
Staphylococcus Epidermidis ◽  
Metallic Nanoparticles ◽  
Antibacterial Properties ◽  
Gram Negative Bacteria ◽  
Gram Positive ◽  
Gram Negative ◽  
Gram Positive Bacteria ◽  
Live Bacteria

Current research on the antibacterial properties of implant surfaces has focused on using titanium nanotubes (TNTs) with diameters of 100 and 200 nm, which simultaneously show the best antibacterial properties, poor osseointegration, and ability to immobilize proteins. Therefore, the research aimed to develop an implantable material based on titanium dioxide nanotubes with a diameter of 50 nm doped with silver (AgNPs) and gold nanoparticles (AuNPs), indicating good absorption and antibacterial properties. Moreover, metallic nanoparticles deposited by varying methods should maintain sphericity and lack of agglomeration. For this purpose, the surface charge, wettability, stability of nanoparticles, and antibacterial properties against Gram-positive and Gram-negative bacteria, i. e., Staphylococcus epidermidis, Streptococcus mutans, and Pseudomonas aeruginosa , were performed. Obtained results indicate a greater resistance to leaching of silver nanoparticles compared to gold nanoparticles. These results are reflected in microbiological studies, both into the time and the effectiveness of the implantable material's antibacterial activity. A greater antibacterial effect of AgNPs than AuNPs has been confirmed. Also, AgNPs inhibit the multiplication of Gram-negative bacteria to a greater extent than Gram-positive bacteria. It has been proven that the TNT platforms deposited with metal nanoparticles via the voltammetric method are more effective in deactivating microorganisms. Besides, the results have proven that smaller TNTs effectively reduce live bacteria as nanotubes with a diameter of 100 and 200 nm.

scholarly journals Synthesis, characterization and antibacterial activity of silver nanoparticles using Rhazya stricta

PeerJ ◽  
2018 ◽  
Vol 6 ◽  
pp. e6086 ◽  
Author(s):  
Adeeb Shehzad ◽  
Munibah Qureshi ◽  
Saima Jabeen ◽  
Rizwan Ahmad ◽  
Amira H. Alabdalall ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Antibacterial Activity ◽  
Metallic Nanoparticles ◽  
Fourier Transforms ◽  
Root Extract ◽  
Gram Positive ◽  
Rhazya Stricta ◽  
Vis Spectroscopy ◽  
Wide Range ◽  
Pharmaceutical Industries

Background Green synthesis of metallic nanoparticles has gained significant attention in the field of nanomedicine as an environment-friendly and cost-effective alternative in comparison with other physical and chemical methods. Several metals such as silver, gold, iron, titanium, zinc, magnesium and copper have been subjected to nanoformulation for a wide range of useful applications. Silver nanoparticles (AgNPs) are playing a major role in the field of nanomedicine and nanotechnology. They are widely used in diagnostics, therapeutic and pharmaceutical industries. Studies have shown potential inhibitory antimicrobial, anti-inflammatory and antiangiogenesis activities of AgNPs. Methods AgNPs have been synthesized using silver nitrate and methanolic root extract of Rhazya stricta that belongs to the Apocynaceae family. Stability and dispersion of nanoparticles were improved by adding xylitol. Synthesized nanoparticles were characterized by UV–Vis spectroscopy, scanning electron microscopy, energy dispersive spectroscopy, X-ray diffractometer and Fourier transforms infrared spectroscopy. Furthermore, the antibacterial effect of the plant extract and the nanoparticles were evaluated against gram-positive (Bacillus subtilis) and gram-negative (Escherichia coli) bacteria. Results The average size of AgNPs synthesized, was 20 nm with the spherical shape. Rhazya stricta based nanoparticles exhibited improved antibacterial activity against both gram-positive and negative strains.

scholarly journals Titanium Oxide (TiO2) Nanoparticles for Treatment of Wound Infection

2021 ◽  
Vol 15 (1) ◽  
pp. 437-451
Author(s):  
Hani A. Alhadrami ◽  
Raniyah A.M Shoudri
Keyword(s):  
Antibacterial Activity ◽  
Wound Infection ◽  
Titanium Oxide ◽  
Metallic Nanoparticles ◽  
Antibacterial Activities ◽  
Wound Infections ◽  
Bacterial Strains ◽  
Tio2 Nps ◽  
Causative Agents ◽  
New Formulation

Wound infections is one of the major problems worldwide. Millions of people around the world require several medical treatments for wound infections. The extensive use of antibiotics to treat wound infection leads to emerging new microbial strains that are resistant to many antibiotics. There is a growing concern on the emergence and re-emergence of drug-resistant pathogens such as multi-resistant bacterial strains. Hence, the development of new antimicrobial compounds or the modification of those that already exist to improve antibacterial activity is a high research priority. Metallic nanoparticles (NPs) are considered as new alternative treatment for wound infection with superior antibacterial activity. In this study, new formulation of titanium oxide (TiO2) NPs with different sizes were synthesized and characterized. Genotoxicity, mutagenicity and antibacterial activities of TiO2 NPs against the causative agents of wound infection were investigated. Antibacterial activity of TiO2 NPs was conducted against three ATCC® bacterial strains: methicillin-resistant Staphylococcus aureus (MRSA), Escherichia coli and Pseudomonas aeruginosa. The results clearly illustrate a superior antibacterial activity of all newly formulated TiO2 NPs against the most causative agents of wound infection. Most of our TiO2 NPs showed non-genotoxic and non-mutagenic results at the maximum concentrations. Findings of this study will enhance the future of the therapeutic strategies against the resistant pathogenic strains that cause wound infections.

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