scholarly journals Prenatal Diagnosis of Down Syndrome

2018 ◽  
Author(s):  
Iliescu Dominic-Gabriel ◽  
Drăgușin Roxana-Cristina
Keyword(s):  
Down Syndrome ◽  
Prenatal Diagnosis

scholarly journals Amniocentesis increases level of anxiety in women with invasive prenatal diagnosis of Down syndrome

2015 ◽  
Vol 34 (2) ◽  
pp. 112 ◽  
Author(s):  
Yanuarita Tursinawati ◽  
Serene Thain ◽  
Christina Choi ◽  
George Heong Yeo Seow
Keyword(s):  
Down Syndrome ◽  
Prenatal Diagnosis ◽  
Pregnant Women ◽  
Gestational Age ◽  
Perceived Risk ◽  
Linear Regression Analysis ◽  
Chorionic Villus ◽  
Chorionic Villus Sampling ◽  
Psychological Responses ◽  
Depression Anxiety Stress Scale

Backgound <br />Invasive prenatal diagnosis (PND) through amniocentesis and chorionic villus sampling (CVS) can detect Down syndrome. Pregnant women usually experience a variety of psychological responses associated with invasive PND. This study is intended to assess depression, anxiety and stress levels and the factors related to their psychological responses in pregnant women with invasive prenatal diagnosis of Down syndrome.<br /><br />Methods <br />A cross sectional study was conducted at Kandang Kerbau Women’s and Children’s Hospital, Singapore. The psychological responses of 70 women undergoing PND were assessed by Depression Anxiety Stress Scale 21 (DASS 21) questionnaire. A multiple linear regression analysis was used to analyze association between knowledge and perceived risk with psychological responses (CI 95% and significance value p&lt;0.05).<br /><br />Results <br />More than half of the participants had normal anxiety (55.7%), stress (72.8%), depression levels (65.8%). The results revealed significantly higher level of anxiety in women with gestational age &gt;13 weeks who had pursued amniocentesis. Women with no previous children had higher levels of depression and stress. Women who pursued amniocentesis had significantly higher anxiety scores compared to women undergoing CVS (p=0.015).<br /><br />Conclusions <br />Women’s psychological responses are associated with gestational age, type of procedure and parity. The level of anxiety increased in women who underwent amniocentesis for diagnosis of Down syndrome. Knowledge and perceived risk of having a baby with Down syndrome do not seem to have psychological effects to women.

Modified methylated DNA immunoprecipitation protocol for noninvasive prenatal diagnosis of Down syndrome

2018 ◽  
Vol 44 (4) ◽  
pp. 608-613 ◽  
Author(s):  
Fatemeh Karami ◽  
Mohammad R. Noori-Daloii ◽  
Kobra Omidfar ◽  
Mina Tabrizi ◽  
Seddigheh Hantooshzadeh ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Prenatal Diagnosis ◽  
Methylated Dna ◽  
Noninvasive Prenatal Diagnosis

scholarly journals Rapid Prenatal Diagnosis of Down Syndrome Using Quantitative Fluorescent PCR in Uncultured Amniocytes

2004 ◽  
Vol 19 (3) ◽  
pp. 341 ◽  
Author(s):  
Moon-Hee Lee ◽  
Hyun-Mee Ryu ◽  
Do-Jin Kim ◽  
Bom-Yi Lee ◽  
Eun-Hee Cho ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Prenatal Diagnosis ◽  
Fluorescent Pcr ◽  
Quantitative Fluorescent Pcr

scholarly journals Using population-based data to predict the impact of introducing noninvasive prenatal diagnosis for Down syndrome

2010 ◽  
Vol 12 (5) ◽  
pp. 298-303 ◽  
Author(s):  
Marleen R Susman ◽  
David J Amor ◽  
Evelyne Muggli ◽  
Alice M Jaques ◽  
Jane Halliday
Keyword(s):  
Down Syndrome ◽  
Prenatal Diagnosis ◽  
Population Based ◽  
Noninvasive Prenatal Diagnosis ◽  
The Impact

scholarly journals Termination of pregnancy following a prenatal diagnosis of Down syndrome: A qualitative study of the decision-making process of pregnant couples

2018 ◽  
Vol 97 (10) ◽  
pp. 1228-1236 ◽  
Author(s):  
Stina Lou ◽  
Kathrine Carstensen ◽  
Olav Bjørn Petersen ◽  
Camilla Palmhøj Nielsen ◽  
Lone Hvidman ◽  
...  
Keyword(s):  
Decision Making ◽  
Down Syndrome ◽  
Prenatal Diagnosis ◽  
Qualitative Study ◽  
Termination Of Pregnancy ◽  
Decision Making Process

scholarly journals Prenatal Diagnosis of Down Syndrome

10.5772/17414 ◽  
2011 ◽  
Author(s):  
Myungshin Kim ◽  
Jong Chul ◽  
In Yang
Keyword(s):  
Down Syndrome ◽  
Prenatal Diagnosis
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