scholarly journals Cryotherapy for Common Premalignant and Malignant Skin Disorders

2018 ◽  
Author(s):  
Sevgi Akarsu ◽  
Isil Kamberoglu
Keyword(s):  
Skin Disorders ◽  
Malignant Skin

scholarly journals The PI3K/Akt Pathway: Emerging Roles in Skin Homeostasis and a Group of Non-Malignant Skin Disorders

Cells ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 1219
Author(s):  
Yan Teng ◽  
Yibin Fan ◽  
Jingwen Ma ◽  
Wei Lu ◽  
Na Liu ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Akt Pathway ◽  
Skin Disorders ◽  
Phosphatidylinositol 3 Kinase ◽  
Skin Development ◽  
Wide Range ◽  
Malignant Skin ◽  
Solid Foundation ◽  
And Migration ◽  
Poor Outcomes

The phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signaling pathway regulates cell proliferation, differentiation, and migration, along with angiogenesis and metabolism. Additionally, it could mediate skin development and homeostasis. There is much evidence to suggest that dysregulation of PI3K/Akt pathway is frequently associated with several human cutaneous malignancies like malignant melanoma (MM), basal cell carcinoma (BCC), and cutaneous squamous cell carcinoma (SCC), as well as their poor outcomes. Nevertheless, emerging roles of PI3K/Akt pathway cascade in a group of common non-malignant skin disorders including acne and psoriasis, among others, have been recognized. The enhanced understanding of dysfunction of PI3K/Akt pathway in patients with these non-malignant disorders has offered a solid foundation for the progress of updated therapeutic targets. This article reviews the latest advances in the roles of PI3K/Akt pathway and their targets in the skin homeostasis and progression of a wide range of non-malignant skin disorders and describes the current progress in preclinical and clinical researches on the involvement of PI3K/Akt pathway targeted therapies.

Non-malignant Skin Disorders: Tumors, Hyperplasia, Dermatoses

2008 ◽  
pp. 147-159
Author(s):  
Renato G. Panizzon ◽  
Rene O. Mirimanoff ◽  
Michael Heinrich Seegenschmiedt
Keyword(s):  
Skin Disorders ◽  
Malignant Skin

Acitretin treatment in (pre)malignant skin disorders of renal transplant recipients: histologic and immunohistochemical effects

2004 ◽  
Vol 50 (2) ◽  
pp. 189-196 ◽  
Author(s):  
Jürgen V Smit ◽  
Ruud G.L de Sévaux ◽  
Willeke A.M Blokx ◽  
Peter C.M van de Kerkhof ◽  
Andries J Hoitsma ◽  
...  
Keyword(s):  
Renal Transplant ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Skin Disorders ◽  
Malignant Skin

Safety of Systemic Biologic Agents in the Treatment of Non-malignant Skin Disorders

2017 ◽  
Vol 12 (2) ◽  
Author(s):  
George Badavanis ◽  
Efstathia Pasmatzi ◽  
Alexandra Monastirli ◽  
Dionysios Tsambaos
Keyword(s):  
Biologic Agents ◽  
Skin Disorders ◽  
Malignant Skin

Special Considerations In The Management Of Malignant Skin Lesions About The Eye

1993 ◽  
Vol 26 (2) ◽  
pp. 215-230
Author(s):  
Gerry F. Funk ◽  
Henry T. Hoffman ◽  
Keith D. Carter
Keyword(s):  
Skin Lesions ◽  
Malignant Skin
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