scholarly journals Vertebral Osteonecrosis

Osteonecrosis ◽  
2017 ◽  
Author(s):  
Elizabeth Pérez Hernández ◽  
Eulalio Elizalde Martínez ◽  
Juan Manuel Torres Fernández
Keyword(s):  
Vertebral Osteonecrosis

scholarly journals Gaucher disease presenting with vertebral compression fractures and vertebral osteonecrosis

2015 ◽  
Vol 98 (1) ◽  
pp. 50
Author(s):  
G. Clinckemaillie ◽  
A. Larbi ◽  
P. Omoumi ◽  
J. Manelfe ◽  
B. Dallaudière
Keyword(s):  
Gaucher Disease ◽  
Vertebral Compression Fractures ◽  
Compression Fractures ◽  
Vertebral Osteonecrosis

Bisphosphonates are not associated with vertebral osteonecrosis

2009 ◽  
Vol 27 (4) ◽  
pp. 452-455 ◽  
Author(s):  
David F. Kallmes ◽  
Arash Ehteshami Rad ◽  
Leigh A. Gray ◽  
Robert J. McDonald ◽  
Bart L. Clarke
Keyword(s):  
Vertebral Osteonecrosis

scholarly journals Kümmell’s Disease: Clarifying the Mechanisms and Patients’ Inclusion Criteria

2014 ◽  
Vol 8 (1) ◽  
pp. 288-297 ◽  
Author(s):  
Charalampos Matzaroglou ◽  
Christos S Georgiou ◽  
Andreas Panagopoulos ◽  
Kostantinos Assimakopoulos ◽  
Hans J Wilke ◽  
...  
Keyword(s):  
Vertebral Body ◽  
Clinical Course ◽  
Time Lag ◽  
Radiographic Finding ◽  
Inclusion Criteria ◽  
Radiographic Appearance ◽  
Vertebral Osteonecrosis ◽  
Kummell’S Disease ◽  
Initial Description ◽  
Kümmell’S Disease

The three major causes of vertebral body collapse include infection, malignant neoplasia, and trauma and it may be difficult to distinguish between them, particularly in the presence of severe osteoporosis. In 1891, however, Dr Hermann Kümmell, further added another possibility of vertebral body crush; the delayed posttraumatic collapse. As originally described, this rare clinical entity includes patients, who after a trivial trauma and an asymptomatic clinical course they develop a progressive vertebral body collapse and a painful kyphosis. Although more than a century has passed from its initial description, only few cases have been reported in the literature, whereas the main pathologic eliciting event is still under investigation. As a consequence, great controversy exists regarding the discrete features of the clinical course, its radiographic appearance and the histopathological findings. To explain the time lag between the initial trauma and the occurrence of the vertebral collapse, the hypothesis of ischemic necrosis was advanced. Equation of Kümmell’s disease with vertebral osteonecrosis, however, has wrongly led many authors to report cases of Kümmell’s disease, even in the absence of history of spinal trauma. On the other hand, high coincidence of vertebral osteonecrosis and the pathognomonic radiographic finding of intravertebral vacuum cleft, has further added to the confusion. In this review we present an overview of the literature on Kümmell’s disease, focusing on the different proposed eliciting mechanisms. We also highlight controversial subjects on clinical course, diagnosis and treatment of this entity, in an attempt to further clarify patients’ inclusion criteria.

scholarly journals Percutaneous vertebroplasty in vertebral osteonecrosis (Kümmell's spondylitis)

1999 ◽  
Vol 7 (1) ◽  
pp. E4 ◽  
Author(s):  
Huy M. Do ◽  
Mary E. Jensen ◽  
William F. Marx ◽  
David F. Kallmes
Keyword(s):  
Back Pain ◽  
Mr Imaging ◽  
Vertebral Body ◽  
Chronic Back Pain ◽  
Percutaneous Vertebroplasty ◽  
Fluid Collection ◽  
Compression Fracture ◽  
Response To Therapy ◽  
Vertebral Osteonecrosis

The authors report the clinical symptoms and response to therapy of a series of patients who presented with subacute or chronic back pain due to vertebral osteonecrosis (Kümmell's spondylitis) and who underwent percutaneous vertebroplasty. The authors performed a retrospective chart review of a series of 95 patients in whom 149 painful, nonneoplastic compression fractures were demonstrated and who were treated with percutaneous transpediculate polymethylmethacrylate (PMMA) vertebroplasty. In six of these patients there was evidence of vertebral osteonecrosis, as evidenced by the presence of an intravertebral vacuum cleft on radiography or by intravertebral fluid on magnetic resonance (MR) imaging. Clinical and radiological findings on presentation were noted. Technical aspects of the vertebroplasty technique were compiled. Response to therapy, defined as qualitative change in pain severity and change in level of activity, was noted immediately following the procedure and at various periods on follow-up reviews. One man and five women, who ranged in age from 72 to 90 years (mean 81 years), were treated. Each patient had one compression fracture. The fractures were at T-11 (one patient), L-1 (two patients), L-3 (two patients), and L-4 (one patient). The pain pattern was described as severe and localized to the affected vertebra, and sometimes radiated along either flank. Pain duration ranged from 2 to 12 weeks, and the pain was refractory to conservative therapy that consisted of bedrest, analgesics, and external bracing. At the time of treatment, all patients were bedridden because of severe back pain. In all patients either plain radiographic or computerized tomography evidence of intravertebral vacuum cleft or MR imaging evidence of vertebral fluid collection consistent with avascular necrosis of the vertebral body was demonstrated. Four patients underwent bilateral transpediculate vertebroplasty, and two patients underwent unilateral transpediculate vertebroplasty. The fracture cavities were specifically targeted for PMMA injection. Additional fortification of the osteoporotic vertebral body trabeculae was also performed when feasible. "Cavitygrams" or intraosseous venograms with gentle contrast injection were obtained prior to application of cement mixture. In all patients subjective improvement in pain and increased mobility were demonstrated posttreatment. The follow-up period ranged from 4 to 24 hours after treatment. Two patients made additional office visits at 1 and 3 months, respectively. Patients presenting with vertebral osteonecrosis (Kümmell's spondylitis) often suffer from local paraspinous or referred pain. When performing vertebroplasty on these patients, confirmation of entry into the fracture cavities with contrast-enhanced "cavitygrams" should be performed prior to injection of PMMA cement. The response to vertebroplasty with regard to amelioration of pain and improved mobility is encouraging.

Vertebral Osteonecrosis Related to Intradiscal Electrothermal Therapy

Spine ◽  
2003 ◽  
Vol 28 (9) ◽  
pp. E161-E164 ◽  
Author(s):  
Brian M. Scholl ◽  
Steven M. Theiss ◽  
Robert Lopez-Ben ◽  
Mark Kraft
Keyword(s):  
Vertebral Osteonecrosis

AB1053 Vertebral osteonecrosis: Clinical and radiological characteristics of a series of 18 cases

2013 ◽  
Vol 71 (Suppl 3) ◽  
pp. 698.10-698
Author(s):  
C.C. Macía Villa ◽  
M.D.C. Prieto Morales ◽  
M. Ahijόn Lana ◽  
W.A. Sifuentes Giraldo ◽  
I. Gallego Rivera ◽  
...  
Keyword(s):  
Vertebral Osteonecrosis

Vertebral osteonecrosis in an HIV-infected patient

2012 ◽  
Vol 17 (8) ◽  
pp. 1627-1630 ◽  
Author(s):  
Walter A Sifuentes Giraldo ◽  
Cristina C Macía Villa ◽  
Carmen Quereda Rodríguez-Navarro ◽  
Mónica Vázquez Díaz
Keyword(s):  
Infected Patient ◽  
Vertebral Osteonecrosis

Vertebral Osteonecrosis Associated with Pancreatitis in a Woman with Pancreas Divisum: A Case Report

2004 ◽  
Vol 86 (11) ◽  
pp. 2504-2508 ◽  
Author(s):  
Freyr Gauti Sigmundsson ◽  
Peter B. Andersen ◽  
Henrik Daa Schroeder ◽  
Karsten Thomsen
Keyword(s):  
Case Report ◽  
Pancreas Divisum ◽  
Vertebral Osteonecrosis ◽  
Pancréas Divisum

Vertebral osteonecrosis associated with sarcoidosis

2005 ◽  
Vol 2 (2) ◽  
pp. 222-225 ◽  
Author(s):  
Manabu Ito ◽  
Makoto Motomiya ◽  
Kuniyoshi Abumi ◽  
Osamu Shirado ◽  
Yoshihisa Kotani ◽  
...  
Keyword(s):  
Progressive Collapse ◽  
Systemic Disease ◽  
Laboratory Data ◽  
Spinal Tumor ◽  
Bone Fragility ◽  
Lymph Node Biopsy ◽  
Histological Evaluation ◽  
Content Type ◽  
Vertebral Osteonecrosis ◽  
Osteoporotic Vertebral Collapse

✓ Sarcoidosis is a systemic disease commonly affecting lung, skin, or eye. Sarcoidosis involved with osseous structures occurs in approximately 5% of patients, usually involving small bones. Spinal sarcoidosis is extremely rare. The authors report on a man in whom examination of a subclavicular lymph node biopsy specimen and its spinal involvement had established a diagnosis of sarcoidosis and who had undergone steroid therapy. Despite intensive conservative treatment, the authors observed progressive collapse of L-2 requiring spinal decompressive and reconstructive surgeries. Histological evaluation of the collapsed vertebra did not show the typical noncaseating granuloma; rather, the authors observed osteonecrosis of the entire L-2 structure without reactive cellular activities. Other potential diagnoses including infectious disease, metastatic spinal tumor, and osteoporotic vertebral collapse were excluded based on laboratory data, imaging studies, and pathological findings. Complete necrosis of the entire L-2 vertebra in this case can be considered as a rare clinical manifestation of spinal sarcoidosis. Because of osteopenia and systemic bone fragility, combined anterior—posterior spinal reconstructive surgery was performed to restabilize the severely damaged spine.

Vertebral Osteonecrosis and Percutaneous Vertebroplasty

2008 ◽  
Vol 4 (4) ◽  
pp. 162-165
Author(s):  
Lluís Rosselló ◽  
Francesc Pallisó ◽  
Jesús Ferrer ◽  
Elisa Docampo ◽  
Joan Calvet ◽  
...  
Keyword(s):  
Percutaneous Vertebroplasty ◽  
Vertebral Osteonecrosis
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