scholarly journals Application of Computer Modeling to Drug Discovery: Case Study of PRK1 Kinase Inhibitors as Potential Drugs in Prostate Cancer Treatment

Author(s):  
Abdulkarim Najjar ◽  
Fidele Ntie-Kang ◽  
Wolfgang Sippl
Author(s):  
Sarah C. Kobrin ◽  
Alex Conway

Men diagnosed with early stage prostate cancer will very likely survive many years after their prostate cancer treatment, regardless of which standard treatment is used. This case study describes a situation in which all standard treatments are supported by evidence but side effects vary greatly. In this situation, a partnership is needed between the doctor and the patient to choose the best option. This case study gives a brief overview of the complexities of choosing a treatment for early state prostate cancer and how implementation science is needed to (1) consider effectiveness and implementation together and (2) identify factors that inhibit and enhance the implementation and sustainability of shared decision-making.


2018 ◽  
Vol 19 (5) ◽  
pp. 1359 ◽  
Author(s):  
Ekaterina Nevedomskaya ◽  
Simon Baumgart ◽  
Bernard Haendler

2004 ◽  
Vol 171 (4S) ◽  
pp. 284-284
Author(s):  
Yi Lu ◽  
Jun Zhang ◽  
Ben Beheshti ◽  
Ximing J. Yang ◽  
Syamal K. Bhattacharya ◽  
...  

2017 ◽  
Vol 5 (4) ◽  
pp. e219-e228 ◽  
Author(s):  
Stephanie R. Reading ◽  
Kimberly R. Porter ◽  
Jeffrey M. Slezak ◽  
Teresa N. Harrison ◽  
Joy S. Gelfond ◽  
...  

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