scholarly journals Identification of Biomarkers Associated with Cancer Using Integrated Bioinformatic Analysis

2021 ◽  
Author(s):  
Arpana Parihar ◽  
Shivani Malviya ◽  
Raju Khan

Among the leading cause of death cancer ranked in top position. Early diagnosis of cancer holds promise for reduced mortality rate and speedy recovery. The cancer associated molecules being altered in terms of under/over expression when compared to normal cells and thus could act as biomarkers for therapeutic designing and drug repurposing. The information about the known cancer associated biomarkers can be exploited for targeting of cancer specifically in terms of selective personalized medicine designing. This chapter deals with various types of biomarkers associated with different types of cancer and their identification using integrated bioinformatic analysis. Besides, a brief insight on integrated bioinformatics analysis tools and databases have also been discussed.

2017 ◽  
Vol 112 (3) ◽  
pp. 461a ◽  
Author(s):  
Sung Cheol Kim ◽  
Navneet Dogra ◽  
Benjamin H. Wunsch ◽  
Joshua T. Smith ◽  
Stacey M. Gifford ◽  
...  

Author(s):  
Prableen Kaur ◽  
Manik Sharma

Genetic Algorithms (GA), Ant Colony Optimization (ACO), Particle Swarm Optimization (PSO) and Artificial Bee Colonies (ABC) are some vital nature inspired computing (NIC) techniques. These approaches have been used in early prophecy of various diseases. This article analyzes the efficacy of various NIC techniques in diagnosing diverse critical human disorders. It is observed that GA, ACO, PSO and ABC have been successfully used in early diagnosis of different diseases. As compared to ACO, PSO and ABC algorithms, GA has been extensively used in diagnosis of ecology, cardiology and endocrinologist. In addition, from the last six years of research, it has been observed that the accuracy accomplished using GA, ACO, PSO and ABC in the early diagnosis of cancer, diabetes and cardio problems lies between 73.5%-99.7%, 70%-99.2%, 80%-98% and 76.4% to 99.98% respectively. Furthermore, ACO, PSO and ABC are found to be best suited in diagnosing lung, prostate and breast cancer respectively. Moreover, the hybrid use of NIC techniques produces better results as compared to their individual use.


The Analyst ◽  
2019 ◽  
Vol 144 (18) ◽  
pp. 5504-5510 ◽  
Author(s):  
Fei Yin ◽  
Liqi Liu ◽  
Xia Sun ◽  
Laiyong Hou ◽  
Yu Lu ◽  
...  

Simultaneous detection of different types of cancer biomarkers (nucleic acids and proteins) could facilitate early diagnosis of cancer and clinical treatment.


BMJ ◽  
1953 ◽  
Vol 2 (4827) ◽  
pp. 85-85
Author(s):  
H. O gilvie

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