scholarly journals Skin Aging: Implications of UV Radiation, Reactive Oxygen Species and Natural Antioxidants

2021 ◽  
Author(s):  
Bristy Ganguly ◽  
Manisha Hota ◽  
Jyotsnarani Pradhan
Keyword(s):  
Reactive Oxygen Species ◽  
Ultraviolet Radiation ◽  
Functional Decline ◽  
Treatment Strategies ◽  
Reactive Oxygen ◽  
Natural Antioxidants ◽  
Skin Aging ◽  
Oxygen Species ◽  
Chronological Aging ◽  
Skin Wrinkles

Skin aging is an inescapable phenomenon that leads to a functional decline of the skin along with emergence of characteristics features such as coarse skin, wrinkles, loss of elasticity and an overall aged appearance. While chronological aging is inevitable occurring with time, photoaging is contributed by Ultraviolet radiation and reactive oxygen species principally which can boost the skin aging process. These processes can however be ameliorated with the help of treatment strategies, one of them being supplementation with antioxidants. This chapter summarizes diverse mechanisms underlying skin aging with regards to Ultraviolet radiation and reactive oxygen species along with role of antioxidants in impeding these processes. Further, it provides a glimpse towards possible future explorations and challenges dominating the field of skin aging.

scholarly journals Role of Natural Antioxidants on Neuroprotection and Neuroinflammation

Antioxidants ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 608
Author(s):  
Domenico Nuzzo
Keyword(s):  
Reactive Oxygen Species ◽  
Energy Metabolism ◽  
Respiratory Chain ◽  
Reactive Oxygen ◽  
Natural Antioxidants ◽  
Oxygen Species

All cells continuously generate reactive oxygen species (ROS) through the respiratory chain during the energy metabolism process [...]

scholarly journals Role of NADPH Oxidase-Mediated Reactive Oxygen Species in Podocyte Injury

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Shan Chen ◽  
Xian-Fang Meng ◽  
Chun Zhang
Keyword(s):  
Reactive Oxygen Species ◽  
Nadph Oxidase ◽  
Epithelial To Mesenchymal Transition ◽  
Kidney Diseases ◽  
Treatment Strategies ◽  
Reactive Oxygen ◽  
Glomerular Sclerosis ◽  
Oxygen Species ◽  
Podocyte Injury ◽  
Mesenchymal Transition

Proteinuria is an independent risk factor for end-stage renal disease (ESRD) (Shankland, 2006). Recent studies highlighted the mechanisms of podocyte injury and implications for potential treatment strategies in proteinuric kidney diseases (Zhang et al., 2012). Reactive oxygen species (ROS) are cellular signals which are closely associated with the development and progression of glomerular sclerosis. NADPH oxidase is a district enzymatic source of cellular ROS production and prominently expressed in podocytes (Zhang et al., 2010). In the last decade, it has become evident that NADPH oxidase-derived ROS overproduction is a key trigger of podocyte injury, such as renin-angiotensin-aldosterone system activation (Whaley-Connell et al., 2006), epithelial-to-mesenchymal transition (Zhang et al., 2011), and inflammatory priming (Abais et al., 2013). This review focuses on the mechanism of NADPH oxidase-mediated ROS in podocyte injury under different pathophysiological conditions. In addition, we also reviewed the therapeutic perspectives of NADPH oxidase in kidney diseases related to podocyte injury.

scholarly journals Experimental Hepatic Carcinogenesis: Oxidative Stress and Natural Antioxidants

2017 ◽  
Vol 5 (5) ◽  
pp. 686-691 ◽  
Author(s):  
Velid Unsal ◽  
Ergül Belge-Kurutaş
Keyword(s):  
Oxidative Stress ◽  
Reactive Oxygen Species ◽  
Reactive Oxygen ◽  
Natural Antioxidants ◽  
Toxic Substances ◽  
Oxygen Species ◽  
Leading Role ◽  
Hepatic Carcinogenesis ◽  
Key Factor ◽  
Tumour Promoters

Hepatocellular carcinoma is one of the most common cancers in the world, and it is influenced by agents such as DEN, 2-AAF, phenobarbital, alcohol, aflatoxin B1 metabolite or hepatitis viruses (B and C). Oxidative stress is becoming recognized as a key factor in the progression of hepatocarcinogenesis. Reactive oxygen species can play a leading role in initiation and promotion of hepatic carcinogenesis. The metabolites of DEN Diethylnitrosamine (DEN) mediate the binding of tumour promoters by covalently binding to the DNA with one or two oxidation-providing electrons. 2-AAF is the inducer of DEN, and it is involved in tumour formation in the bladder and liver. Reactive Oxygen species (ROS); carbohydrates, lipids, DNA and enzymes, such as affect all important structures. Additionally, an excessive amount of ROS is highly toxic to cells. Antioxidants are protects against ROS, toxic substances, carcinogens. This review focuses on the literature on studies of Hepatic Carcinogenesis, oxidative stress and antioxidant therapy.

Controlling Reactive Oxygen Species in Skin at Their Source to Reduce Skin Aging

2010 ◽  
Vol 13 (2-3) ◽  
pp. 165-167 ◽  
Author(s):  
Dale G. Kern ◽  
Zoe D. Draelos ◽  
Christiaan Meadows ◽  
D. James Morré ◽  
Dorothy M. Morré
Keyword(s):  
Reactive Oxygen Species ◽  
Reactive Oxygen ◽  
Skin Aging ◽  
Oxygen Species

scholarly journals Similar Stress Responses are Elicited by Copper and Ultraviolet Radiation in the Aquatic Plant Lemna gibba: Implication of Reactive Oxygen Species as Common Signals

2003 ◽  
Vol 44 (12) ◽  
pp. 1320-1329 ◽  
Author(s):  
T. Sudhakar Babu ◽  
Tariq A. Akhtar ◽  
Mark A. Lampi ◽  
Sridevi Tripuranthakam ◽  
D. George Dixon ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Ultraviolet Radiation ◽  
Stress Responses ◽  
Aquatic Plant ◽  
Reactive Oxygen ◽  
Lemna Gibba ◽  
Oxygen Species

scholarly journals Impact of plasma jet vacuum ultraviolet radiation on reactive oxygen species generation in bio-relevant liquids

2015 ◽  
Vol 22 (12) ◽  
pp. 122008 ◽  
Author(s):  
H. Jablonowski ◽  
R. Bussiahn ◽  
M. U. Hammer ◽  
K.-D. Weltmann ◽  
Th. von Woedtke ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Ultraviolet Radiation ◽  
Vacuum Ultraviolet ◽  
Reactive Oxygen Species Generation ◽  
Reactive Oxygen ◽  
Plasma Jet ◽  
Oxygen Species ◽  
Vacuum Ultraviolet Radiation
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