scholarly journals Role of Melatonin and the Biological Clock in Regulating Lactation in Seasonal Sheep

10.5772/66208 ◽  
2017 ◽  
Author(s):  
Edyta Molik ◽  
Dorota Zięba-Przybylska
Keyword(s):  
Development ◽  
1990 ◽  
Vol 109 (2) ◽  
pp. 323-328 ◽  
Author(s):  
S.V. Evsikov ◽  
L.M. Morozova ◽  
A.P. Solomko

The hypothesis suggesting that the blastocoele is able to form only at a definite nucleocytoplasmic ratio was tested. We compared the development of preimplantation mouse embryos under different conditions. The results demonstrated that the start of cavitation is not dependent on the number of cell divisions. Thus, a definite nucleocytoplasmic ratio is not required for blastocoele formation to start. Our studies on embryos with microsurgically altered cytoplasm content provided evidence for the following biological clock mechanism: a change in the cell program of morphogenesis needs definite concentration of the products of a previous genetic program.


2018 ◽  
Vol 51 (1) ◽  
pp. 139-150
Author(s):  
Ajitha Adaikkalam ◽  
Srivani Sankaran ◽  
Sheeja S. Rajan ◽  
Perumal Subramanian

2007 ◽  
Vol 42 (1-2) ◽  
pp. 22-27 ◽  
Author(s):  
Felix Kreier ◽  
Andries Kalsbeek ◽  
Hans P. Sauerwein ◽  
Eric Fliers ◽  
Johannes A. Romijn ◽  
...  

2001 ◽  
Vol 280 (3) ◽  
pp. H1391-H1399 ◽  
Author(s):  
F. A. J. L. Scheer ◽  
G. J. Ter Horst ◽  
J. van der Vliet ◽  
R. M. Buijs

The suprachiasmatic nucleus (SCN) is the mammalian biological clock that generates the daily rhythms in physiology and behavior. Light can phase shift the rhythm of the SCN but can also acutely affect SCN activity and output, e.g., output to the pineal. Recently, multisynaptic SCN connections to other organs were also demonstrated. Moreover, they were shown to affect those organs functionally. The aim of the present study was to investigate the role of the SCN in the regulation of the heart. First, we demonstrated that heart rate (HR) in SCN-intact, but not SCN-lesioned (SCNx), male Wistar rats had a clear circadian rhythm, which was not caused by locomotor activity. Second, we demonstrated that light at night reduces HR in intact but not in SCNx rats. Finally, we demonstrated the presence of a multisynaptic autonomic connection from SCN neurons to the heart with the retrograde pseudorabies virus tracing technique. Together, these results demonstrate that the SCN affects the heart in rats and suggest that this is mediated by a neuronal mechanism.


2013 ◽  
Vol 67 ◽  
pp. 569-583
Author(s):  
Piotr Chrościcki ◽  
Michał Usarek ◽  
Jadwiga Bryla

2018 ◽  
Vol 6 (3) ◽  
pp. 149-154
Author(s):  
Vijaylaxmi Ramprasad Reddy ◽  
Ashwini A.Shitre

Ayurveda is the science of life, guiding in maintaining health and curing of diseases by balancing doshas-dhatus-malas and jatharagni. Ahara, nidra and brahmacharya form the pillars of health as per Ayurveda. Lifestyle diseases are those diseases whose occurrence is based on the daily habits of people and are a result of an inappropriate relationship of people with their environment. The main factors contributing to lifestyle diseases include bad food habits, physical inactivity and disturbed biological clock. Occupational lifestyle diseases include those caused by the factors present in the vicinity of pollutants. These factors are also responsible for environmental allergies. So, a healthy lifestyle must be adopted with a proper balanced diet, physical activity and by giving due respect to biological clock. Healthy lifestyle methods are now easily achievable with nutritional counselling, exercise training, de-addiction programmes, regular medical check-ups and stress management techniques. Ayurveda provides better solution in the guidelines of proper dietary management, lifestyle advises, panchakarma procedures like detoxification and bio-purification procedures, medicaments and rejuvenation therapies. In this revolutionized era, we cannot stop doing the developmental work, but we can certainly reduce our ailments with simple and effective measures in our lives as suggested in Ayurveda, the science of life.


2020 ◽  
pp. 33-49
Author(s):  
Andrey Viktorovich Antsyborov ◽  
Anna Valerievna Kalinchuk ◽  
Irina Vladimirovna Dubatova

Presently, a lot of data indicate that the disturbance of mechanisms underlying the regulation of sleep-waking cycle coincides with the mechanisms underlying the development of depression. The disturbance of circadian rhythms is one of the core factors in the genesis of the most affective disorders including depression, which indicates the role of the internal biological clock in the pathophysiology of affective disorders. The episodes of depression, mania or hypomania may result from the disturbances in endogenous biological timing. In this review, we have summarized the literature data obtained in animal models or in the patients with affective pathology, in which the connection between the function of sleep and depression was demonstrated. Specifically, we highlight the mechanisms underlying sleep dysfunction during depression (imbalance of circadian rhythms, melatonin metabolism and mechanisms of neuroinflammatory dysregulation) and provide an evidence for the link between sleep function and depression (sleep disturbances during depressive episodes, the effects of pharmacotherapy, chronotherapy, the effect of sleep deprivation, comorbidity of obstructive sleep apnea and depression).


2005 ◽  
Vol 69 (4) ◽  
pp. 835-843 ◽  
Author(s):  
Felicita Scapini ◽  
Claudia Rossano ◽  
Giovanni M. Marchetti ◽  
Elfed Morgan

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