scholarly journals Transperineal Targeted Biopsy with Real-Time Fusion Image of Multiparametric Magnetic Resonance Image and Transrectal Ultrasound Image for the Diagnosis of Prostate Cancer

Author(s):  
Sunao Shoji
Author(s):  
Troncone Raffaella ◽  
Coda Marco ◽  
Aliberti Daniele ◽  
Ciccone Vincenzo ◽  
Carbone Mattia

Magnetic resonance imaging is the fastest and least invasive diagnostic method for the study of the prostate. The method's multiparametricity allows the acquisition of the images highlighting different characteristics in relation to the different sampling sequences. In particular, the MRI investigation plays a role in: • risk stratification and staging of the tumor, therefore active surveillance • detection of prostate cancer; • localization and characterization of prostate cancer before performing a procedure (pre-biopsy, pre-surgery, or radiation therapy); • procedural guide (targeted biopsy guide). The study protocol includes T2-weighted sequences on an axial and sagittal plane, diffusion-weighted sequences for the functional study (DWI) with high b values, contrast dynamic sequences (DCE-MRI), T1-weighted sequences with a large FOV. The study protocol here presented follows the latest PI-RADS v2.1 guidelines. The axial scan plans are acquired according to the anatomical axis of the gland. In our protocol we add a further neutral T2 weighing, a sequence that will be subsequently used for the coupling of images with fusion techniques, such as target-biopsy. The adoption of PI-RAADS v2.1, the most recent update of the system, improves the assessment of intra-patient injury variability and simplifies the general assessment of the prostate in magnetic resonance imaging. The magnetic resonance examination thus obtained allows the correct overlap of the lesion anatomy with the ultrasound image TRUS acquired with the Fusion technique, used for targeted biopsy sampling.


2018 ◽  
Vol 26 (2) ◽  
pp. 317-319 ◽  
Author(s):  
Yuta Inoue ◽  
So Ushijima ◽  
Takumi Shiraishi ◽  
Atsuko Fujihara ◽  
Fumiya Hongo ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Dirk G. Engehausen ◽  
Karl Engelhard ◽  
Siegfried A. Schwab ◽  
Michael Uder ◽  
Sven Wach ◽  
...  

Aim. To explore the potential of transrectal magnetic resonance image- (MRI-) guided biopsies of the prostate in a patient cohort with prior negative ultrasound guided biopsies.Patients and Methods. Ninety-six men with suspected prostate cancer underwent MRI-guided prostate biopsies under real-time imaging control in supine position.Results. Adenocarcinoma of the prostate was detected in 39 of 96 patients. For individual core biopsies, MRI yielded a sensitivity of 93.0% and a specificity of 94.4%. When stratifying patients according to the free-to-total prostate-specific antigen (PSA) ratio, the prostate cancer discovery rate was significantly higher in the group with ratios less than 0.15 (57.1%).Conclusion. MRI-guided biopsy of the prostate is a diagnostic option for patients with suspected prostate cancer and a history of repeatedly negative transrectal ultrasound-guided biopsies. Combined with the free-to-total PSA ratio, it is a highly effective method for detecting prostate cancer.


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