scholarly journals Genetics of Allergic Asthma and Current Perspectives on Therapeutic Management

10.5772/63651 ◽  
2016 ◽  
Author(s):  
Mina Youssef ◽  
Cynthia Kanagaratham ◽  
Mohamed I. Saad ◽  
Danuta Radzioch
Keyword(s):  
Allergic Asthma ◽  
Therapeutic Management

Sequential degranulation of eosinophils induced by antigen or autocoids in allergic humans

1986 ◽  
Vol 44 ◽  
pp. 354-355
Author(s):  
Kate W. Sjoerdsma ◽  
W. James Metzger
Keyword(s):  
Allergic Rhinitis ◽  
Bronchoalveolar Lavage ◽  
Allergic Asthma ◽  
Skin Test ◽  
Positive Skin Test ◽  
Positive Skin ◽  
Human Eosinophil ◽  
Asthmatic Patients ◽  
Allergic Asthmatic ◽  
History Of

Eosinophils are important to the pathogenesis of allergic asthma, and are increased in bronchoalveolar lavage within four hours after bronchoprovocation of allergic asthmatic patients, and remain significantly increased up to 24 hours later. While the components of human eosinophil granules have been recently isolated and purified, the mechanisms of degranulation have yet to be elucidated.We obtained blood from two volunteers who had a history of allergic rhinitis and asthma and a positive skin test (5x5mm wheal) to Alternaria and Ragweed. Eosinophils were obtained using a modification of the method described by Roberts and Gallin.

The Collaborative Medical and Behavioral Management of Chronic Cough

2009 ◽  
Vol 19 (2) ◽  
pp. 49-57
Author(s):  
Brian E. Petty ◽  
Seth H. Dailey
Keyword(s):  
Medical Care ◽  
Chronic Cough ◽  
Therapeutic Management ◽  
Ambulatory Setting ◽  
Behavioral Management ◽  
Speech Language Pathologists ◽  
Speech Language Pathologist ◽  
The Many ◽  
Frequent Reason

Abstract Chronic cough is the most frequent reason cited by patients for seeking medical care in an ambulatory setting and may account for 10% to 38% of a pulmonologist's practice. Because chronic cough can be caused by or correlated with a wide array of disorders and behaviors, the diagnosis of etiologic factors and determination of appropriate therapeutic management in these cases can prove to be daunting for the physician and speech-language pathologist alike. This article will describe the phenomenon of chronic cough, discuss the many etiologic factors to consider, and review some of the more common ways in which speech-language pathologists and physicians collaborate to treat this challenging condition.

Therapy of allergic asthma

2001 ◽  
Vol 58 (5) ◽  
pp. 315-320
Author(s):  
C. Bucher ◽  
E. W. J. Russi
Keyword(s):  
Allergic Asthma ◽  
Medikamentöse Therapie ◽  
Asthma Bronchiale ◽  
Spezifische Immuntherapie ◽  
Medikamentöse Behandlung

Asthma bronchiale ist eine chronische entzündliche Erkrankung der Atemwege, die gehäuft bei Atopikern auftritt. Die Therapie des allergischen Asthma bronchiale stützt sich auf drei Pfeiler: Das Vermeiden einer Allergenexposition, eine medikamentöse Therapie sowie in ausgewählten Fällen eine spezifische Immuntherapie (SIT). Ein völliges Meiden des Allergenkontaktes ist in der Regel nicht zu erreichen, weshalb die meisten Asthmatiker eine medikamentöse Behandlung benötigen. Dafür stehen moderne und wirksame Medikamente zur Verfügung. Die SIT hat sich vor allem bei der Pollenallergie bewährt. Wegen des in der Regel chronischen und wechselhaften Verlaufs sowie mitunter lebensbedrohlichen Situationen sollte der Patient über die Natur der Erkrankung, die Therapie, notwendige Kontrollen, sowie Maßnahmen bei einer plötzlichen Verschlechterung sorgfältig instruiert werden. Allgemein gilt für die Therapie des Asthma bronchiale, dass die Compliance des Patienten für den Therapieerfolg entscheidend ist.

TLR ligands alter the phenotype of experimental acute allergic asthma in mice

Pneumologie ◽  
2011 ◽  
Vol 65 (12) ◽  
Author(s):  
L Lunding ◽  
C Vock ◽  
H Fehrenbach ◽  
M Wegmann
Keyword(s):  
Allergic Asthma

Distribution and efficacy of a GATA-3-specific DNAzyme in experimental allergic asthma models

Pneumologie ◽  
2012 ◽  
Vol 66 (06) ◽  
Author(s):  
A Turowska ◽  
T Dicke ◽  
N Baumgartl ◽  
J Kuhlmann ◽  
H Renz ◽  
...  
Keyword(s):  
Allergic Asthma ◽  
Experimental Allergic Asthma ◽  
Experimental Allergic

Mechanism of bronchopulmonary C-fiber hyperexcitability in allergic asthma: Loss of TRPV1 inhibition by GDNF downregulation?

Pneumologie ◽  
2012 ◽  
Vol 66 (06) ◽  
Author(s):  
R Nandigama ◽  
A Weske ◽  
S Wiegand ◽  
W Kummer ◽  
C Nassenstein
Keyword(s):  
Allergic Asthma ◽  
C Fiber

Bronchopulmonary C-fiber activation in allergic asthma: Novel evidence for an involvement of the FGF/FGFR1-IIIc system

Pneumologie ◽  
2012 ◽  
Vol 66 (06) ◽  
Author(s):  
R Boehmer ◽  
R Nandigama ◽  
S Wiegand ◽  
J Lee ◽  
W Kummer ◽  
...  
Keyword(s):  
Allergic Asthma ◽  
C Fiber
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