scholarly journals Perspectives of Conductive Polymers Toward Smart Biomaterials for Tissue Engineering

10.5772/63555 ◽  
2016 ◽  
Author(s):  
Anca Filimon
Keyword(s):  
Tissue Engineering ◽  
Conductive Polymers ◽  
Smart Biomaterials

Importance of crosslinking strategies in designing smart biomaterials for bone tissue engineering: A systematic review

2019 ◽  
Vol 96 ◽  
pp. 941-954 ◽  
Author(s):  
Gopal Shankar Krishnakumar ◽  
Sowndarya Sampath ◽  
Shalini Muthusamy ◽  
Mary Arlene John
Keyword(s):  
Systematic Review ◽  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Smart Biomaterials

scholarly journals Recent advances on polydiacetylene-based smart materials for biomedical applications

2020 ◽  
Vol 4 (4) ◽  
pp. 1089-1104 ◽  
Author(s):  
Fang Fang ◽  
Fanling Meng ◽  
Liang Luo
Keyword(s):  
Mechanical Properties ◽  
Drug Delivery ◽  
Tissue Engineering ◽  
Smart Materials ◽  
Biomedical Applications ◽  
Recent Advances ◽  
Smart Biomaterials

This review summarized most recent advances of designing strategies of polydiacetylene-based smart biomaterials with unique colorimetric and mechanical properties, as well as their applications in biosensing, drug delivery, and tissue engineering.

scholarly journals Intrinsically Conductive Polymers for Striated Cardiac Muscle Repair

2021 ◽  
Vol 22 (16) ◽  
pp. 8550
Author(s):  
Arsalan Ul Haq ◽  
Felicia Carotenuto ◽  
Fabio De Matteis ◽  
Paolo Prosposito ◽  
Roberto Francini ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Cardiac Muscle ◽  
Cardiac Tissue ◽  
Cultured Cells ◽  
Conductive Polymers ◽  
Signal Propagation ◽  
Scar Tissue ◽  
Cardiac Tissue Engineering ◽  
Conductive Component

One of the most important features of striated cardiac muscle is the excitability that turns on the excitation-contraction coupling cycle, resulting in the heart blood pumping function. The function of the heart pump may be impaired by events such as myocardial infarction, the consequence of coronary artery thrombosis due to blood clots or plaques. This results in the death of billions of cardiomyocytes, the formation of scar tissue, and consequently impaired contractility. A whole heart transplant remains the gold standard so far and the current pharmacological approaches tend to stop further myocardium deterioration, but this is not a long-term solution. Electrically conductive, scaffold-based cardiac tissue engineering provides a promising solution to repair the injured myocardium. The non-conductive component of the scaffold provides a biocompatible microenvironment to the cultured cells while the conductive component improves intercellular coupling as well as electrical signal propagation through the scar tissue when implanted at the infarcted site. The in vivo electrical coupling of the cells leads to a better regeneration of the infarcted myocardium, reducing arrhythmias, QRS/QT intervals, and scar size and promoting cardiac cell maturation. This review presents the emerging applications of intrinsically conductive polymers in cardiac tissue engineering to repair post-ischemic myocardial insult.

scholarly journals Cyclodextrin-Polypyrrole Coatings of Scaffolds for Tissue Engineering

Polymers ◽  
2019 ◽  
Vol 11 (3) ◽  
pp. 459 ◽  
Author(s):  
Jan Lukášek ◽  
Šárka Hauzerová ◽  
Kristýna Havlíčková ◽  
Kateřina Strnadová ◽  
Karel Mašek ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Conductive Polymers ◽  
Composite Scaffold ◽  
Cell Types ◽  
Hexanoic Acid ◽  
Spectroscopic Techniques ◽  
In Vitro Experiments ◽  
Engineering Applications ◽  
Different Cell Types

Polypyrrole is one of the most investigated conductive polymers used for tissue engineering applications because of its advantageous properties and the ability to promote different cell types’ adhesion and proliferation. Together with β-cyclodextrin, which is capable of accommodating helpful biomolecules in its cavity, it would make a perfect couple for use as a scaffold for tissue engineering. Such scaffolds were prepared by the polymerisation of 6-(pyrrol-3-yl)hexanoic acid on polycaprolactone microfibres with subsequent attachment of β-cyclodextrin on the polypyrrole layer. The materials were deeply characterised by several physical and spectroscopic techniques. Testing of the cyclodextrin enriched composite scaffold revealed its better performance in in vitro experiments compared with pristine polycaprolactone or polypyrrole covered polycaprolactone scaffolds.

Smart biomaterials design for tissue engineering and regenerative medicine

Biomaterials ◽  
2007 ◽  
Vol 28 (34) ◽  
pp. 5068-5073 ◽  
Author(s):  
Mark E. Furth ◽  
Anthony Atala ◽  
Mark E. Van Dyke
Keyword(s):  
Tissue Engineering ◽  
Regenerative Medicine ◽  
Smart Biomaterials
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